Genomics
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35 Alleles
60 Clones
16 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0263865:15 | Smr:15 |
| FBgn0263865:14 | Smr:14 |
| FBgn0263865:16 | Smr:16 |
| FBgn0263865:11 | Smr:11 |
| FBgn0263865:9 | Smr:9 |
| FBgn0263865:8 | Smr:8 |
| FBgn0263865:7 | Smr:7 |
| FBgn0263865:6 | Smr:6 |
| FBgn0263865:5 | Smr:5 |
| FBgn0263865:4 | Smr:4 |
| FBgn0263865:3 | Smr:3 |
| FBgn0263865:2 | Smr:2 |
| FBgn0263865:13 | Smr:13 |
| FBgn0263865:12 | Smr:12 |
| FBgn0263865:1 | Smr:1 |
| FBgn0263865:10 | Smr:10 |
8 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0333765-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333766-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333767-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333768-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333765-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333766-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333767-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333768-3-prime-utr | Drosophila melanogaster |
Other
36 Pathways
- PPARA Activates Gene Expression,
- Gene Expression,
- Loss of Function of TGFBR2 in Cancer,
- BMAL1:CLOCK/NPAS2 Activates Circadian Expression,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer,
- TGF-beta receptor signaling activates SMADs,
- Generic Transcription Pathway,
- Loss of Function of TGFBR1 in Cancer,
- Fatty acid, triacylglycerol, and ketone body metabolism,
- Loss of Function of SMAD4 in Cancer,
- RORA Activates Circadian Expression,
- Signaling by NODAL,
- Circadian Clock,
- Downregulation of SMAD2/3:SMAD4 transcriptional activity,
- TGFBR1 LBD Mutants in Cancer,
- Signaling by ERBB4,
- Disease,
- TGFBR2 Kinase Domain Mutants in Cancer,
- Nuclear signaling by ERBB4,
- Developmental Biology,
- Signaling Pathways,
- TGFBR1 KD Mutants in Cancer,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha),
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- Metabolism,
- Circadian Repression of Expression by REV-ERBA,
- Metabolism of lipids and lipoproteins,
- Transcriptional Regulation of White Adipocyte Differentiation,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,
- Signaling by Activin,
- Signaling by TGF-beta Receptor Complex,
- SMAD4 MH2 Domain Mutants in Cancer,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- Signaling by TGF-beta Receptor Complex in Cancer,
- Loss of Function of SMAD2/3 in Cancer
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32225 | NCBI Entrez Gene identifiers | FBgn0265523 |
| 58618 | BioGRID | FBgn0265523 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster |
18 Introns
70 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Smr | Decreased lipid droplet area | -2.422487813 | 19067489 | |
| Lipid storage | Smr | Decreased lipid droplet area | -3.561741251 | 19067489 | |
| Lipid storage | Smr | Decreased lipid droplet area | -3.352831742 | 19067489 | |
| Lipid storage | Smr | Decreased lipid droplet area | -0.591024046 | 19067489 | |
| Lipid storage | Smr | none | 0.071595175 | 19067489 | |
| Lipid storage | Smr | none | -0.707134641 | 19067489 | |
| Lipid storage | Smr | none | 1.711022153 | 19067489 | |
| Lipid storage | Smr | none | 0.517201946 | 19067489 | |
| Lipid storage | Smr | none | 0.096192724 | 19067489 | |
| E. coli / S. aureus infection | Smr | Cell death | np | 11912489 | |
| Cytokinesis regulation | Smr | Binucleate cells with decreased viability | weak | 15547975 | |
| Wnt signaling | Smr | Increased Wnt reporter activity | 4.4 | 15817814 | |
| Hedgehog signaling | Smr | Decreased Hedgehog reporter activity | -3.01 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | Smr | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Constitutive protein secretion and Golgi organization (1) | Smr | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | Smr | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Smr | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Smr | none | sp | 16496002 | |
| Candida albicans phagocytosis (1) | Smr | Decreased Candida albicans phagocytosis | np | 16336044 | |
| Candida albicans phagocytosis (2) | Smr | none | 50 | 16336044 | |
| Candida albicans phagocytosis (3) | Smr | Decreased latex beads phagocytosis | 30 | 16336044 | |
| Dendrite pattern formation | Smr | none | np | 16547170 | |
| Combinatorial effect with methyl methanesulphonate (2) | Smr | none | sp | 19543366 | |
| Mutant human huntingtin aggregation | Smr | Decreased mutant human huntingtin aggregation | <= -2 | 19789644 | |
| Heat nociception (1) | Smr | none | -1.17 | 21074052 | |
| Heat nociception (1) | Smr | none | -0.14 | 21074052 | |
| Heart development and function (1) | Smr | none | 1 | 20371351 | |
| Heart development and function (1) | Smr | none | 1 | 20371351 | |
| Notch pathway regulation (4) | Smr | none | 0 | 19363474 | |
| Notch pathway regulation (4) | Smr | Completely lethal (pupal) | sp | 19363474 |
