Genomics
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18 Alleles
49 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0071188-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0071188-3-prime-utr | Drosophila melanogaster |
Other
34 Pathways
- Interleukin-1 signaling,
- Toll Like Receptor 4 (TLR4) Cascade,
- MyD88 dependent cascade initiated on endosome,
- IRAK2 mediated activation of TAK1 complex,
- Activated TLR4 signalling,
- Toll Like Receptor TLR6:TLR2 Cascade,
- TRAF6 mediated induction of TAK1 complex,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1,
- Toll Like Receptor 9 (TLR9) Cascade,
- MyD88:Mal cascade initiated on plasma membrane,
- Cytokine Signaling in Immune system,
- NOD1/2 Signaling Pathway,
- Toll Like Receptor 5 (TLR5) Cascade,
- Toll-Like Receptors Cascades,
- Signaling by Interleukins,
- MyD88 cascade initiated on plasma membrane,
- MAP kinase activation in TLR cascade,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- activated TAK1 mediates p38 MAPK activation,
- IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation,
- IRAK1 recruits IKK complex,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Immune System,
- IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation,
- Toll Like Receptor 10 (TLR10) Cascade,
- TRIF-mediated TLR3/TLR4 signaling,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Toll Like Receptor 3 (TLR3) Cascade,
- Toll Like Receptor TLR1:TLR2 Cascade,
- MyD88-independent cascade,
- Innate Immune System,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex,
- Toll Like Receptor 2 (TLR2) Cascade
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31746 | NCBI Entrez Gene identifiers | FBgn0265464 |
| 58214 | BioGRID | FBgn0265464 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster |
13 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Traf6 | none | 0.605779186 | 19067489 | |
| Lipid storage | Traf6 | none | -0.011029697 | 19067489 | |
| Cell size and cell-cycle regulation (1) | Traf6 | none | sp | 16496002 | |
| Heart development and function | Traf6 | Heart tube assembly defects | np | 14684833 | |
| Muscle morphogenesis and function (1) | Traf6 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | Traf6 | none | np | 20220848 | |
| Heat nociception (1) | Traf6 | none | -0.31 | 21074052 | |
| Heart development and function (1) | Traf6 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Traf6 | none | 0.721518987341772 | 19520911 | |
| Notch pathway regulation (4) | Traf6 | none | 0 | 19363474 | |
| Notch pathway regulation (4) | Traf6 | none | 0 | 19363474 | |
| Adiposity regulation (1) | Traf6 | none | 0.505 | 20074523 | |
| Hippo pathway regulation | Traf6 | none | -1.5 | 23263283 |
