Genomics
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55 Alleles
142 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0001297:4 | kay:4 |
| FBgn0001297:5 | kay:5 |
| FBgn0001297:1 | kay:1 |
| FBgn0001297:6 | kay:6 |
| FBgn0001297:7 | kay:7 |
| FBgn0001297:2 | kay:2 |
| FBgn0001297:3 | kay:3 |
5 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0099988 | kay |
| FBtr0339165 | kay |
| FBtr0290076 | kay |
| FBtr0099990 | kay |
| FBtr0099989 | kay |
10 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0099988-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0099989-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0099990-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0290076-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0339165-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0099988-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0099989-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0099990-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0290076-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0339165-3-prime-utr | Drosophila melanogaster |
Other
82 Pathways
- GRB2 events in EGFR signaling,
- IRAK2 mediated activation of TAK1 complex,
- RAF/MAP kinase cascade,
- NGF signalling via TRKA from the plasma membrane,
- Signalling to RAS,
- Downstream signaling of activated FGFR,
- SOS-mediated signalling,
- Signaling by EGFR,
- SHC-mediated signalling,
- FRS2-mediated cascade,
- Prolonged ERK activation events,
- IRS-mediated signalling,
- Gastrin-CREB signalling pathway via PKC and MAPK,
- SHC-related events,
- Toll Like Receptor 2 (TLR2) Cascade,
- SHC-related events triggered by IGF1R,
- Toll Like Receptor 3 (TLR3) Cascade,
- ARMS-mediated activation,
- Developmental Biology,
- Signaling by Interleukins,
- Insulin receptor mediated signaling,
- DAP12 signaling,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- DAP12 interactions,
- Oxidative Stress Induced Senescence,
- DINR-mediated activation,
- Cellular Senescence,
- Activated TLR4 signalling,
- NCAM signaling for neurite out-growth,
- Insulin receptor signalling cascade,
- Axon guidance,
- Signaling by SCF-KIT,
- Toll Like Receptor 10 (TLR10) Cascade,
- Signaling by GPCR,
- SHC1 events in ERBB4 signaling,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Signalling to p38 via RIT and RIN,
- Toll Like Receptor 5 (TLR5) Cascade,
- Signaling by FGFR in disease,
- IRS-related events,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- Activation of the AP-1 family of transcription factors,
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1,
- Signaling by PDGF,
- MyD88 dependent cascade initiated on endosome,
- IRS-related events triggered by IGF1R,
- Signaling by ERBB4,
- Cellular responses to stress,
- Signaling by NGF,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- SHC1 events in ERBB2 signaling,
- MyD88-independent cascade,
- Signaling Pathways,
- Immune System,
- Toll Like Receptor 4 (TLR4) Cascade,
- Interleukin-2 signaling,
- Toll Like Receptor 9 (TLR9) Cascade,
- FCERI mediated MAPK activation,
- Insulin signaling pathway,
- Signaling by FGFR,
- Cytokine Signaling in Immune system,
- MyD88:Mal cascade initiated on plasma membrane,
- MAPK targets/ Nuclear events mediated by MAP kinases,
- Toll Like Receptor TLR1:TLR2 Cascade,
- Fc epsilon receptor (FCERI) signaling,
- Signaling by Leptin,
- Downstream signal transduction,
- MyD88 cascade initiated on plasma membrane,
- Innate Immune System,
- Signalling to ERKs,
- Toll-Like Receptors Cascades,
- Signaling by ERBB2,
- TRIF-mediated TLR3/TLR4 signaling,
- Disease,
- Insulin receptor recycling,
- MAP kinase activation in TLR cascade,
- GRB2 events in ERBB2 signaling,
- SHC1 events in EGFR signaling,
- IGF1R signaling cascade,
- Signaling by EGFR in Cancer,
- Frs2-mediated activation
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 3772082 | NCBI Entrez Gene identifiers | FBgn0001297 |
| 533679 | BioGRID | FBgn0001297 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
57 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Cell size regulation | kay | none | -2.97 | 19216764 | |
| Lipid storage | kay | none | -0.090531967 | 19067489 | |
| Lipid storage | kay | none | -0.674044098 | 19067489 | |
| Lipid storage | kay | none | -0.311019201 | 19067489 | |
| Lipid storage | kay | none | -3.865207624 | 19067489 | |
| Lipid storage | kay | none | -0.422456242 | 19067489 | |
| Lipid storage | kay | none | -0.68791368 | 19067489 | |
| ERK signaling | kay | ERK activation increased | strong | 17086199 | |
| Innate immunity | kay | Decreased IMD reporter activity | np | 16163390 | |
| Mycobacterial infection (1) - M. fortuitum infection | kay | Decreased M. fortuitum intracellular infection | 3.4 | measurement after 3 days | 16020694 |
| Cell size and cell-cycle regulation (1) | kay | Increased G1 DNA content, decreased G1 cell size | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | kay | none | 1.241 | 16496002 | |
| Cell size and cell-cycle regulation (3) | kay | none | 432 | 16496002 | |
| Heart development and function | kay | Heart tube assembly defects, heart patterning defects | np | 14684833 | |
| Dendrite pattern formation | kay | none | np | 16547170 | |
| Mutant human huntingtin aggregation | kay | Increased mutant human huntingtin aggregation | 1.5 - 2 | 19789644 | |
| Muscle morphogenesis and function (1) | kay | none | np | 20220848 | |
| Heat nociception (1) | kay | none | 0.38 | 21074052 | |
| Heat nociception (1) | kay | none | -0.02 | 21074052 | |
| Heat nociception (1) | kay | none | 0.38 | 21074052 | |
| Heart development and function (1) | kay | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | kay | none | -0.59 | 19520911 | |
| Serratia marcescens infection (1) | kay | none | -0.0454545454545454 | 19520911 | |
| Notch pathway regulation (4) | kay | Bristle morphology defects, planar polarity defects, notum malformation migration, overproliferation | sp | 19363474 | |
| Notch pathway regulation (4) | kay | Bristle morphology defects, planar polarity defects, notum malformation migration, overproliferation | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | kay | Increased P-JNK protein expression with PGN | 3.06 | 15 min PGN induction | 19893628 |
| PGN-induced dJNK phosphorylation | kay | Increased P-JNK protein expression with PGN | 3.56 | 60 min PGN induction | 19893628 |
| Notch induced transcription | kay | none | 3.5878 | without Notch stimulation | 20959007 |
| Notch induced transcription | kay | Upregulation of Notch pathway after Notch stimulation | 2.5995 | N(delta)ecn Notch stimulation | 20959007 |
| Notch induced transcription | kay | Downregulation of Notch pathway after Notch stimulation | -1.927 | N(delta)ecn Notch stimulation | 20959007 |
