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Gene : Atx2 D. melanogaster

DB identifier  ? FBgn0041188 Secondary Identifier  ? CG5166
Name  ? Ataxin-2 Source  FlyBase
  • synonyms:
  • GH27029,
  • CG5166,
  • FBgn0062074,
  • anon-fast-evolving-2E1,
  • l(3)06490,
  • SCA2,
  • BEST:GH27029,
  • dSCA2,
  • CG5166a,
  • anon-WO0140519.1,
  • FBan0005166,
  • FBgn0041188,
  • FBgn0010892,
  • Ataxin 2,
  • anon-WO0118547.351,
  • Dataxin-2,
  • anon-EST:fe2E1,
  • FBgn0044786,
  • FBgn0025221,
  • ATAXIN-2,
  • Atxain-2,
  • FBgn0063367,
  • Datx2,
  • ATX2,
  • FBgn0038338

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0218877 Atx2[DG08112]   Drosophila melanogaster
FBal0284701 Atx2[Dm-p.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0136144 Atx2[EP3145]   Drosophila melanogaster
FBal0188134 Atx2[e00368]   Drosophila melanogaster
FBal0141944 Atx2[EP3022]   Drosophila melanogaster
FBal0009566 Atx2[06490]   Drosophila melanogaster
FBal0285119 Atx2[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0285120 Atx2[DeltaPAM2.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0280933 Atx2[DeltaC1.Scer\UAS]   Drosophila melanogaster
FBal0141945 Atx2[06490PE]   Drosophila melanogaster
FBal0141941 Atx2[X2]   Drosophila melanogaster
FBal0141942 Atx2[X1]   Drosophila melanogaster
FBal0286784 Atx2[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286785 Atx2[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0141943 Atx2[Scer\UAS.cSa]   Drosophila melanogaster
FBal0263302 Atx2[HMS01392]   Drosophila melanogaster
FBal0198800 Atx2[GD11562]   Drosophila melanogaster
FBal0230738 Atx2[KK100423]   Drosophila melanogaster

78 Clones

Secondary Identifier DB identifier
AA433256 FBcl0000427
AT28392 FBcl0034927
AT13587 FBcl0034935
AT05170 FBcl0034937
AT22221 FBcl0034943
AT20874 FBcl0034945
AT03709 FBcl0034947
EK063229 FBcl0058166
EK040513 FBcl0058316
EK249657 FBcl0058330
EK240957 FBcl0058336
EK066231 FBcl0058342
EK294438 FBcl0058352
EK200141 FBcl0058384
EK093449 FBcl0058404
EK175137 FBcl0058410
EK165716 FBcl0058442
EK039258 FBcl0058456
EK257027 FBcl0058462
EK122118 FBcl0058466
EK277524 FBcl0058472
EK262635 FBcl0058486
EK254451 FBcl0058502
EK228532 FBcl0058508
EC22746 FBcl0070245
EP15806 FBcl0086197
EP21102 FBcl0088523
EP09701 FBcl0088529
EP18646 FBcl0088531
EP14441 FBcl0088537

9 Exons

DB identifier Symbol
FBgn0041188:1 Atx2:1
FBgn0041188:4 Atx2:4
FBgn0041188:5 Atx2:5
FBgn0041188:6 Atx2:6
FBgn0041188:8 Atx2:8
FBgn0041188:2 Atx2:2
FBgn0041188:9 Atx2:9
FBgn0041188:7 Atx2:7
FBgn0041188:3 Atx2:3

4 Transcripts

DB identifier Gene
FBtr0083100 Atx2
FBtr0083101 Atx2
FBtr0083099 Atx2
FBtr0344377 Atx2

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083099-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0083100-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0083101-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0344377-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083099-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083100-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083101-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0344377-3-prime-utr Drosophila melanogaster

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41883 NCBI Entrez Gene identifiers FBgn0041188
66945 BioGRID FBgn0041188

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1497.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1257.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1271.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1476.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1405.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3207.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3165.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2303.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1272.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2452.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2597.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 980.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2357.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1560.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2066.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1423.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2828.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2258.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1799.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1469.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2117.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1485.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1879.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2121.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1169.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3798.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1037.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1252.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 825.0
FBgn0041188 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1026.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0041188:2_FBgn0041188:4 Drosophila melanogaster
intron_FBgn0041188:4_FBgn0041188:5 Drosophila melanogaster
intron_FBgn0041188:5_FBgn0041188:6 Drosophila melanogaster
intron_FBgn0041188:6_FBgn0041188:9 Drosophila melanogaster
intron_FBgn0041188:5_FBgn0041188:7 Drosophila melanogaster
intron_FBgn0041188:1_FBgn0041188:4 Drosophila melanogaster
intron_FBgn0041188:6_FBgn0041188:8 Drosophila melanogaster
intron_FBgn0041188:3_FBgn0041188:4 Drosophila melanogaster

41 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Atx2 none 0.048697999   19067489
Lipid storage Atx2 none -0.288681286   19067489
Lipid storage Atx2 none 0.377392514   19067489
Lipid storage Atx2 none -0.65499728   19067489
Neural outgrowth Atx2 Excess branching np   18604272
Alternative splicing Atx2 none sp   15492211
Wnt signaling Atx2 Increased Wnt reporter activity 6.2   15817814
Hedgehog signaling Atx2 Decreased Hedgehog reporter activity -2.8   16311596
Constitutive protein secretion and Golgi organization (1) Atx2 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Atx2 none sp   16496002
Cell size and cell-cycle regulation (1) Atx2 none sp   16496002
Cell size and cell-cycle regulation (1) Atx2 none sp   16496002
Candida albicans phagocytosis (1) Atx2 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Atx2 Decreased Escherichia coli phagocytosis 32   16336044
Candida albicans phagocytosis (3) Atx2 Decreased latex beads phagocytosis 37   16336044
Heart development and function Atx2 Heart patterning defects np   14684833
Ca2+ channel regulation Atx2 Decreased Ca2+ influx 1   16645049
Microtubule assembly and organization Atx2 none np   18463163
Mutant human huntingtin aggregation Atx2 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Atx2 Lethal np   20220848
Muscle morphogenesis and function (1) Atx2 Lethal np   20220848
Heat nociception (1) Atx2 none 1.22   21074052
Heat nociception (1) Atx2 none -0.36   21074052
Heart development and function (1) Atx2 none 1   20371351
Serratia marcescens infection (1) Atx2 none -0.292134831460674   19520911
Notch pathway regulation (4) Atx2 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Atx2 Completely lethal (pupal) sp   19363474
Hh pathway regulation Atx2 none -0.0510122344032227   17903264
Hh pathway regulation Atx2 none 0.0165039224013503   17903264
Self-renewal and differentiation in neural stem cells Atx2 Neuroblast larger cell size, lethal sp   21549331

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