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Gene : cact D. melanogaster

DB identifier  ? FBgn0000250 Secondary Identifier  ? CG5848
Name  ? cactus Source  FlyBase
  • synonyms:
  • dip6,
  • BG:DS02740.15,
  • cac,
  • FBgn0000250,
  • FBan0005848,
  • 5848,
  • CG5848,
  • fs(2)ltoRN48,
  • NFkappabeta1A,
  • FBgn0013453,
  • NF-kappa-B inhibitor cactus,
  • n(2)k17003,
  • CACT,
  • Cactus,
  • female-sterile-(2)-ltoRN48

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136 Alleles

DB identifier Symbol Allele Class Organism
FBal0281046 cact[MI07289]   Drosophila melanogaster
FBal0266326 cact[GL00627]   Drosophila melanogaster
FBal0245273 cact[DeltaN125.DeltaPEST.hs]   Drosophila melanogaster
FBal0245274 cact[DeltaN125.DeltaPEST.Scer\UAS]   Drosophila melanogaster
FBal0245322 cact[HM04020]   Drosophila melanogaster
FBal0101479 cact[k17027]   Drosophila melanogaster
FBal0180580 cact[d10397]   Drosophila melanogaster
FBal0180579 cact[e00778]   Drosophila melanogaster
FBal0180581 cact[c05394]   Drosophila melanogaster
FBal0180582 cact[c04150]   Drosophila melanogaster
FBal0180583 cact[c03252]   Drosophila melanogaster
FBal0030687 cact[255]   Drosophila melanogaster
FBal0286500 cact[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286501 cact[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0101480 cact[k17003]   Drosophila melanogaster
FBal0030692 cact[BQ] gain of function allele Drosophila melanogaster
FBal0030693 cact[E10] gain of function allele Drosophila melanogaster
FBal0030699 cact[E19]   Drosophila melanogaster
FBal0030708 cact[P1]   Drosophila melanogaster
FBal0030709 cact[P3]   Drosophila melanogaster
FBal0030710 cact[P5]   Drosophila melanogaster
FBal0030711 cact[P6]   Drosophila melanogaster
FBal0030712 cact[P7]   Drosophila melanogaster
FBal0101481 cact[k08106f]   Drosophila melanogaster
FBal0147240 cact[KG07677]   Drosophila melanogaster
FBal0057708 cact[SA4] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0001510 cact[4]   Drosophila melanogaster
FBal0155520 cact[2R-121-11]   Drosophila melanogaster
FBal0042903 cact[DeltaPEST]   Drosophila melanogaster
FBal0001509 cact[3] loss of function allele Drosophila melanogaster

138 Clones

Secondary Identifier DB identifier
Dmel_neb_002935_0829_3615 FBcl0374619
Dmel_dig_005494_0633_2245 FBcl0374620
EP07964 FBcl0087799
EP06764 FBcl0088099
EK195709 FBcl0100718
EK228337 FBcl0100808
EK215847 FBcl0100826
EK257664 FBcl0100836
EK186823 FBcl0100882
EK154434 FBcl0100888
EK149413 FBcl0100894
EK244507 FBcl0100938
EK215529 FBcl0101606
EK004519 FBcl0101632
EK205505 FBcl0101788
EK247226 FBcl0101872
EK073327 FBcl0101888
GH21759 FBcl0122109
HL04371 FBcl0149872
LD10168 FBcl0157987
LD13068 FBcl0157995
LD19965 FBcl0157998
LD05260 FBcl0157999
LD03773 FBcl0158000
LD19013 FBcl0158001
LD15008 FBcl0158002
LD14691 FBcl0158003
LD10835 FBcl0158004
LD16234 FBcl0158007
LD17086 FBcl0158008

12 Exons

DB identifier Symbol
FBgn0000250:11 cact:11
FBgn0000250:8 cact:8
FBgn0000250:7 cact:7
FBgn0000250:6 cact:6
FBgn0000250:5 cact:5
FBgn0000250:4 cact:4
FBgn0000250:2 cact:2
FBgn0000250:10 cact:10
FBgn0000250:1 cact:1
FBgn0000250:3 cact:3
FBgn0000250:9 cact:9
FBgn0000250:12 cact:12

5 Transcripts

DB identifier Gene
FBtr0080844 cact
FBtr0337081 cact
FBtr0080845 cact
FBtr0080846 cact
FBtr0080847 cact

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080844-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080845-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080846-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080847-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0337081-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080844-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080845-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080846-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080847-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0337081-3-prime-utr Drosophila melanogaster

Interactions

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Other

45 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34969 NCBI Entrez Gene identifiers FBgn0000250
60980 BioGRID FBgn0000250

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1845.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3443.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1401.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1009.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1049.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2274.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4100.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1792.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 975.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1580.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4301.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1335.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1025.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 726.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4261.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1437.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1940.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1217.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1040.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1188.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1248.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 6083.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1527.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1405.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1597.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6563.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 6069.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3774.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2528.0
FBgn0000250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2149.0

11 Introns

DB identifier
Organism . Name
intron_FBgn0000250:12_FBgn0000250:8 Drosophila melanogaster
intron_FBgn0000250:8_FBgn0000250:7 Drosophila melanogaster
intron_FBgn0000250:7_FBgn0000250:6 Drosophila melanogaster
intron_FBgn0000250:6_FBgn0000250:5 Drosophila melanogaster
intron_FBgn0000250:5_FBgn0000250:4 Drosophila melanogaster
intron_FBgn0000250:4_FBgn0000250:2 Drosophila melanogaster
intron_FBgn0000250:11_FBgn0000250:8 Drosophila melanogaster
intron_FBgn0000250:10_FBgn0000250:8 Drosophila melanogaster
intron_FBgn0000250:4_FBgn0000250:1 Drosophila melanogaster
intron_FBgn0000250:5_FBgn0000250:3 Drosophila melanogaster
intron_FBgn0000250:9_FBgn0000250:7 Drosophila melanogaster

23 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage cact none -1.488170116   19067489
Lipid storage cact none -0.275288994   19067489
ERK signaling cact ERK activation reduced strong   17086199
Cell morphology cact Morphology np   14527345
Cell size and cell-cycle regulation (1) cact Increased G1 cell size sp   16496002
Cell size and cell-cycle regulation (2) cact none 1.25   16496002
Cell size and cell-cycle regulation (3) cact none 455   16496002
Candida albicans phagocytosis (1) cact Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) cact Decreased Escherichia coli phagocytosis 40   16336044
Candida albicans phagocytosis (3) cact Decreased latex beads phagocytosis 21   16336044
Dendrite pattern formation cact none np   16547170
Combinatorial effect with methyl methanesulphonate (2) cact Synthetic lethal with methyl methanesulphonate sp   19543366
Embryonic nervous system development cact Disturbed development of nervous system np   17376868
Blood cell homeostasis regulation (1) cact Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) cact Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) cact Increased melanotic mass formation 12   20540764
Blood cell homeostasis regulation (4) cact none 4.4   20540764
Blood cell homeostasis regulation (5) cact Increased melanotic mass formation 25.4   20540764
RTK-Ras-ERK pathway regulation (1) cact Decreased ERK phosphorylation after EGF stimulation -1.85 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) cact none -0.73 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) cact none 0.22 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) cact none 0.29 30 minutes sSpitz stimulation 22028469
Glycosylation regulation (1) cact none sp   21203496

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