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Gene : CycT D. melanogaster

DB identifier  ? FBgn0025455 Secondary Identifier  ? CG6292
Name  ? Cyclin T Source  FlyBase
  • synonyms:
  • FBgn0023101,
  • cyclin T1,
  • unnamed,
  • dT,
  • anon-74EFc,
  • Dmcyclin T,
  • ORE-14,
  • p124,
  • cyclin T,
  • CyclinT,
  • P-TEFb,
  • dCyclin T,
  • FBgn0025455,
  • FBan0006292,
  • cyclin T2,
  • CG6292

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0249013 CycT[Scer\UAS.T:Disc\RFP-mRFP]   Drosophila melanogaster
FBal0245371 CycT[HM04074]   Drosophila melanogaster
FBal0184241 CycT[c06766]   Drosophila melanogaster
FBal0184242 CycT[c06571]   Drosophila melanogaster
FBal0257457 CycT[HMS00776]   Drosophila melanogaster
FBal0184243 CycT[c06091]   Drosophila melanogaster
FBal0184244 CycT[c04764]   Drosophila melanogaster
FBal0184240 CycT[dsRNA.cNa]   Drosophila melanogaster
FBal0105254 CycT[MtnA.PL]   Drosophila melanogaster
FBal0262528 CycT[GL00037]   Drosophila melanogaster
FBal0105255 CycT[2xMut.MtnA.T:Scer\GAL4]   Drosophila melanogaster
FBal0105253 CycT[MtnA.T:Scer\GAL4]   Drosophila melanogaster
FBal0206715 CycT[GD4130]   Drosophila melanogaster
FBal0216735 CycT[nos.3'UTR.Scer\UAS.P\T]   Drosophila melanogaster
FBal0265524 CycT[MI04468]   Drosophila melanogaster
FBal0222907 CycT[5-HA-2393]   Drosophila melanogaster
FBal0230715 CycT[KK100386]   Drosophila melanogaster
FBal0275067 CycT[NIG.6292R]   Drosophila melanogaster

97 Clones

Secondary Identifier DB identifier
UUGC0058 FBcl0001149
IP16034 FBcl0001622
AT04704 FBcl0006265
AT03454 FBcl0006049
AT02465 FBcl0006113
AT18764 FBcl0006169
AT01728 FBcl0006185
AT02722 FBcl0006201
AT17311 FBcl0006209
AT03646 FBcl0006217
AT11695 FBcl0006225
AT20820 FBcl0006249
AT07636 FBcl0006257
AT30859 FBcl0006273
AT26778 FBcl0006281
AT19807 FBcl0006289
AT26248 FBcl0006305
AT02415 FBcl0006321
AT30449 FBcl0006329
AT17855 FBcl0006985
EP19917 FBcl0075807
EP00710 FBcl0075813
EP14247 FBcl0075819
EP21834 FBcl0075823
EP02964 FBcl0075897
EP02511 FBcl0075923
EK177335 FBcl0077248
EK242704 FBcl0077354
EK056524 FBcl0077596
EN16143 FBcl0092061

7 Exons

DB identifier Symbol
FBgn0025455:3 CycT:3
FBgn0025455:7 CycT:7
FBgn0025455:2 CycT:2
FBgn0025455:6 CycT:6
FBgn0025455:4 CycT:4
FBgn0025455:1 CycT:1
FBgn0025455:5 CycT:5

4 Transcripts

DB identifier Gene
FBtr0333124 CycT
FBtr0333125 CycT
FBtr0075205 CycT
FBtr0075206 CycT

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075205-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075206-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333124-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333125-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075205-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075206-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333124-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333125-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39961 NCBI Entrez Gene identifiers FBgn0025455
65249 BioGRID FBgn0025455

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 832.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 778.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 478.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 474.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 579.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 516.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1719.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 824.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 573.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1094.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1005.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 448.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 563.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 651.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1017.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 581.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1374.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 897.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 451.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 650.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 717.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 799.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 794.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1097.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 686.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2839.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1801.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1477.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 901.0
FBgn0025455 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 846.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0025455:7_FBgn0025455:6 Drosophila melanogaster
intron_FBgn0025455:6_FBgn0025455:3 Drosophila melanogaster
intron_FBgn0025455:3_FBgn0025455:1 Drosophila melanogaster
intron_FBgn0025455:7_FBgn0025455:5 Drosophila melanogaster
intron_FBgn0025455:5_FBgn0025455:3 Drosophila melanogaster
intron_FBgn0025455:3_FBgn0025455:2 Drosophila melanogaster
intron_FBgn0025455:4_FBgn0025455:2 Drosophila melanogaster

54 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage CycT none -0.098368526   19067489
Lipid storage CycT none 1.907737689   19067489
Lipid storage CycT none -0.705399511   19067489
Lipid storage CycT none -0.132847899   19067489
Lipid storage CycT none 0.02688709   19067489
ERK signaling CycT ERK activation increased strong   17086199
Cell morphology CycT Morphology np   14527345
Intracellular Listeria monocytogenes infection CycT Decreased GFP protein expression moderate   16020693
L. monocytogenes infection CycT Fewer infected cells **   16157870
Hedgehog signaling CycT Decreased Hedgehog reporter activity -3.21   16311596
Constitutive protein secretion and Golgi organization (1) CycT Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) CycT none sp   16496002
Cell size and cell-cycle regulation (1) CycT none sp   16496002
Candida albicans phagocytosis (1) CycT none np   16336044
Dendrite pattern formation CycT none np   16547170
Microtubule assembly and organization CycT none np   18463163
Combinatorial effect with methyl methanesulphonate (1) CycT none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) CycT none sp   19543366
Mutant human huntingtin aggregation CycT Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) CycT Lethal np   20220848
Muscle morphogenesis and function (2) CycT Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) CycT none 0.38   21074052
Heart development and function (1) CycT Embryonic lethal or no offspring 0.5   20371351
Heart development and function (2) CycT none 2.85   20371351
Serratia marcescens infection (1) CycT none -1.14285714285714   19520911
Notch pathway regulation (4) CycT Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation CycT Increased P-JNK protein expression with PGN 2.87 60 min PGN induction 19893628
Hh pathway regulation CycT Downregulation of Hh pathway -0.400936056750012   17903264
Hh pathway regulation CycT Downregulation of Hh pathway -0.50112948263912   17903264
Pol II elongation CycT Decreased Hsp70 mRNA expression 20 20 min heat shock 19279664

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