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Gene : Vha55 D. melanogaster

DB identifier  ? FBgn0005671 Secondary Identifier  ? CG17369
Name  ? Vacuolar H[+]-ATPase 55kD subunit Source  FlyBase
  • synonyms:
  • V-ATPase subunit B,
  • V-ATPase B-subunit,
  • vacuolar ATPase B subunit,
  • vacuolar ATP synthase subunit B,
  • FBan0017369,
  • l(3)j2E9,
  • ATP6V1B1,
  • Vacuolar H+ATPase subunit B,
  • Vacuolar H[+]-ATPase 55-kDa B subunit,
  • vha55,
  • l(3)SzA,
  • B subunit of V-ATPase,
  • Vacuolar H[+]-ATPase 55kD B subunit,
  • FBgn0005671,
  • FBgn0011789,
  • FBgn0002345,
  • l(3)87Ca,
  • VAT-2,
  • 1208/13,
  • CG17369,
  • B subunit,
  • SzA,
  • V1 B subunit

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26 Alleles

DB identifier Symbol Allele Class Organism
FBal0246368 Vha55[7a1]   Drosophila melanogaster
FBal0211757 Vha55[CA07634]   Drosophila melanogaster
FBal0181071 Vha55[f03804]   Drosophila melanogaster
FBal0028379 Vha55[j2E9] amorphic allele - genetic evidence Drosophila melanogaster
FBal0083144 Vha55[S120813b]   Drosophila melanogaster
FBal0010421 Vha55[7]   Drosophila melanogaster
FBal0010416 Vha55[2]   Drosophila melanogaster
FBal0010417 Vha55[3]   Drosophila melanogaster
FBal0010423 Vha55[9]   Drosophila melanogaster
FBal0010425 Vha55[11]   Drosophila melanogaster
FBal0010430 Vha55[16]   Drosophila melanogaster
FBal0010424 Vha55[10]   Drosophila melanogaster
FBal0010428 Vha55[14]   Drosophila melanogaster
FBal0010429 Vha55[15]   Drosophila melanogaster
FBal0010419 Vha55[5]   Drosophila melanogaster
FBal0010426 Vha55[12] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0010420 Vha55[6]   Drosophila melanogaster
FBal0010427 Vha55[13]   Drosophila melanogaster
FBal0010415 Vha55[1]   Drosophila melanogaster
FBal0010422 Vha55[8]   Drosophila melanogaster
FBal0010418 Vha55[4]   Drosophila melanogaster
FBal0261374 Vha55[CPTI100063]   Drosophila melanogaster
FBal0261728 Vha55[CPTI002645]   Drosophila melanogaster
FBal0208969 Vha55[GD9363]   Drosophila melanogaster
FBal0279164 Vha55[HMS02132]   Drosophila melanogaster
FBal0258233 Vha55[MI01500]   Drosophila melanogaster

201 Clones

Secondary Identifier DB identifier
ESG013d.E21_E09 FBcl0010477
ESG011b.E7_A09 FBcl0011377
EK302845 FBcl0025242
EK247456 FBcl0025254
EK248724 FBcl0025260
EK221046 FBcl0025264
EK248261 FBcl0025268
EK215257 FBcl0025276
EK225341 FBcl0025280
EK238659 FBcl0025284
EK170060 FBcl0025292
EK220419 FBcl0025306
EK057631 FBcl0025314
EK126123 FBcl0025328
EK049515 FBcl0025336
EK184049 FBcl0025340
EK110608 FBcl0025346
EK290410 FBcl0025362
EK200662 FBcl0025372
ESG011b.E21_A09 FBcl0012689
AT12604 FBcl0045979
AT22165 FBcl0046001
AT22026 FBcl0046005
AT23540 FBcl0046007
AT26081 FBcl0046009
bs20f11 FBcl0058681
bs55g08 FBcl0058683
EC36977 FBcl0073543
EC35777 FBcl0073545
EP17346 FBcl0090083

8 Exons

DB identifier Symbol
FBgn0005671:8 Vha55:8
FBgn0005671:5 Vha55:5
FBgn0005671:3 Vha55:3
FBgn0005671:1 Vha55:1
FBgn0005671:6 Vha55:6
FBgn0005671:7 Vha55:7
FBgn0005671:4 Vha55:4
FBgn0005671:2 Vha55:2

3 Transcripts

DB identifier Gene
FBtr0082670 Vha55
FBtr0082671 Vha55
FBtr0301661 Vha55

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0082670-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082671-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301661-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082670-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082671-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301661-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41550 NCBI Entrez Gene identifiers FBgn0005671
66645 BioGRID FBgn0005671

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1740.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2652.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1889.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2747.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2715.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1915.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2048.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2530.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2093.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2397.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2741.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2021.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2117.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1392.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1900.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1622.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1959.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2451.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1994.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1945.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1534.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2780.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2189.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1782.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1985.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5471.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1729.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 679.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 698.0
FBgn0005671 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 769.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0005671:8_FBgn0005671:5 Drosophila melanogaster
intron_FBgn0005671:5_FBgn0005671:3 Drosophila melanogaster
intron_FBgn0005671:3_FBgn0005671:1 Drosophila melanogaster
intron_FBgn0005671:6_FBgn0005671:3 Drosophila melanogaster
intron_FBgn0005671:7_FBgn0005671:4 Drosophila melanogaster
intron_FBgn0005671:4_FBgn0005671:3 Drosophila melanogaster
intron_FBgn0005671:3_FBgn0005671:2 Drosophila melanogaster

17 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Vha55 none 0.958568308   19067489
Lipid storage Vha55 none 0.958284817   19067489
Intracellular Listeria monocytogenes infection Vha55 Decreased GFP protein expression strong   16020693
L. monocytogenes infection Vha55 Fewer infected cells, less vacuolar escape **   16157870
Mycobacterial infection (1) - M. fortuitum infection Vha55 Decreased M. fortuitum intracellular infection 2.8 measurement after 3 days 16020694
Cell size and cell-cycle regulation (1) Vha55 none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) Vha55 none sp   19543366
Muscle morphogenesis and function (1) Vha55 Lethal np   20220848
Heat nociception (1) Vha55 none -1.17   21074052
Heart development and function (1) Vha55 none 1   20371351
Heart development and function (1) Vha55 none 1   20371351
Heart development and function (2) Vha55 Decreased viability 8.93   20371351
Notch pathway regulation (4) Vha55 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Vha55 Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) Vha55 Upregulation of Notch pathway np   20493818
Notch pathway regulation (3) Vha55 Upregulation of Notch pathway np   20493818
Hippo pathway regulation Vha55 none 0.19   23263283

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