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Gene : EcR D. melanogaster

DB identifier  ? FBgn0000546 Secondary Identifier  ? CG1765
Name  ? Ecdysone receptor Source  FlyBase
  • synonyms:
  • ms(2)06410,
  • FBan0001765,
  • EcR-B,
  • ECR,
  • Ecdysone Receptor,
  • snt,
  • FBgn0021762,
  • DmEcR,
  • ms(2)42A,
  • ecdysteroid receptor,
  • anon-WO0229075.1,
  • FBgn0033064,
  • EcRA,
  • CG8347,
  • CG1765,
  • lie,
  • Dhr23,
  • NR1H1,
  • EcRB1,
  • EcR-A,
  • EcRB-1,
  • snaggletooth,
  • EcdR,
  • EcR-B1,
  • Ecdyson Receptor 1b,
  • DEcR,
  • EcRC,
  • long island expressway,
  • FBgn0011242,
  • ecdysterone receptor,
  • FBgn0062534,
  • FBgn0000546,
  • ECR-C,
  • EcR1b,
  • male sterile(2)42A,
  • ecdysone receptor complex

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146 Alleles

DB identifier Symbol Allele Class Organism
FBal0243252 EcR[554]   Drosophila melanogaster
FBal0243253 EcR[53]   Drosophila melanogaster
FBal0249021 EcR[dsRNA.Scer\UAS.cCa]   Drosophila melanogaster
FBal0282400 EcR[B2-E9K.Scer\UAS]   Drosophila melanogaster
FBal0183875 EcR[DG25401]   Drosophila melanogaster
FBal0183874 EcR[EY16365]   Drosophila melanogaster
FBal0284079 EcR[miRNA.Scer\UAS]   Drosophila melanogaster
FBal0183867 EcR[d08127]   Drosophila melanogaster
FBal0183860 EcR[f03852]   Drosophila melanogaster
FBal0183869 EcR[c04100]   Drosophila melanogaster
FBal0183866 EcR[d08765]   Drosophila melanogaster
FBal0183868 EcR[d00918]   Drosophila melanogaster
FBal0183858 EcR[f07518]   Drosophila melanogaster
FBal0183859 EcR[f04318]   Drosophila melanogaster
FBal0183861 EcR[f02276]   Drosophila melanogaster
FBal0183862 EcR[f02171]   Drosophila melanogaster
FBal0183863 EcR[f01319]   Drosophila melanogaster
FBal0183864 EcR[e03767]   Drosophila melanogaster
FBal0246830 EcR[M544fs]   Drosophila melanogaster
FBal0183865 EcR[e01108]   Drosophila melanogaster
FBal0183870 EcR[c04015]   Drosophila melanogaster
FBal0183871 EcR[c03719]   Drosophila melanogaster
FBal0183872 EcR[c02192]   Drosophila melanogaster
FBal0183873 EcR[c02091]   Drosophila melanogaster
FBal0028433 EcR[06410]   Drosophila melanogaster
FBal0044774 EcR[k04504]   Drosophila melanogaster
FBal0044775 EcR[59C]   Drosophila melanogaster
FBal0044776 EcR[127A]   Drosophila melanogaster
FBal0044777 EcR[OD298A]   Drosophila melanogaster
FBal0044778 EcR[OD1223]   Drosophila melanogaster

201 Clones

Secondary Identifier DB identifier
ESG017c.E21.3_F08 FBcl0006645
bs50e02 FBcl0049509
EC27888 FBcl0064285
EK154759 FBcl0065066
EK208926 FBcl0065086
EK252008 FBcl0065104
EK272754 FBcl0065110
EK180855 FBcl0065118
EK047314 FBcl0065124
EK267144 FBcl0065132
EK113751 FBcl0065136
EK241958 FBcl0065140
EK256533 FBcl0065148
EK305555 FBcl0065156
EK150061 FBcl0065164
EK249613 FBcl0065386
EK057604 FBcl0065400
EK158619 FBcl0065406
EK043443 FBcl0065424
EK063850 FBcl0065428
EK247264 FBcl0065436
EK281252 FBcl0065442
EK263660 FBcl0065446
EK243218 FBcl0065450
HL01604 FBcl0150279
LD10132 FBcl0160144
LD13085 FBcl0160218
LD17664 FBcl0160219
LD20681 FBcl0160221
LD03950 FBcl0160224

16 Exons

DB identifier Symbol
FBgn0000546:16 EcR:16
FBgn0000546:12 EcR:12
FBgn0000546:11 EcR:11
FBgn0000546:7 EcR:7
FBgn0000546:6 EcR:6
FBgn0000546:5 EcR:5
FBgn0000546:2 EcR:2
FBgn0000546:15 EcR:15
FBgn0000546:13 EcR:13
FBgn0000546:3 EcR:3
FBgn0000546:14 EcR:14
FBgn0000546:10 EcR:10
FBgn0000546:8 EcR:8
FBgn0000546:4 EcR:4
FBgn0000546:9 EcR:9
FBgn0000546:1 EcR:1

6 Transcripts

DB identifier Gene
FBtr0086008 EcR
FBtr0086009 EcR
FBtr0086010 EcR
FBtr0302439 EcR
FBtr0086012 EcR
FBtr0086011 EcR

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086008-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086009-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086010-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086011-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086012-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302439-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086008-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086009-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086010-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086011-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086012-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302439-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35540 NCBI Entrez Gene identifiers FBgn0000546
61444 BioGRID FBgn0000546

12 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  
Fly Transcription Factor/microRNA Regulatory Network  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1168.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1617.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 617.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 375.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1140.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 247.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 595.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 512.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 652.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 677.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 670.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 738.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1627.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1048.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2140.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 505.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1428.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 532.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 907.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1331.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2084.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2152.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 896.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1233.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 641.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1641.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1499.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 912.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 992.0
FBgn0000546 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1176.0

17 Introns

DB identifier
Organism . Name
intron_FBgn0000546:15_FBgn0000546:13 Drosophila melanogaster
intron_FBgn0000546:13_FBgn0000546:12 Drosophila melanogaster
intron_FBgn0000546:12_FBgn0000546:11 Drosophila melanogaster
intron_FBgn0000546:11_FBgn0000546:7 Drosophila melanogaster
intron_FBgn0000546:7_FBgn0000546:6 Drosophila melanogaster
intron_FBgn0000546:6_FBgn0000546:5 Drosophila melanogaster
intron_FBgn0000546:5_FBgn0000546:3 Drosophila melanogaster
intron_FBgn0000546:15_FBgn0000546:14 Drosophila melanogaster
intron_FBgn0000546:14_FBgn0000546:12 Drosophila melanogaster
intron_FBgn0000546:5_FBgn0000546:2 Drosophila melanogaster
intron_FBgn0000546:16_FBgn0000546:12 Drosophila melanogaster
intron_FBgn0000546:10_FBgn0000546:8 Drosophila melanogaster
intron_FBgn0000546:8_FBgn0000546:7 Drosophila melanogaster
intron_FBgn0000546:5_FBgn0000546:4 Drosophila melanogaster
intron_FBgn0000546:10_FBgn0000546:7 Drosophila melanogaster
intron_FBgn0000546:9_FBgn0000546:8 Drosophila melanogaster
intron_FBgn0000546:5_FBgn0000546:1 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage EcR none -0.716734299   19067489
Lipid storage EcR none -1.027588017   19067489
Lipid storage EcR none 0.379184002   19067489
Lipid storage EcR none 1.212955951   19067489
Cell size and cell-cycle regulation (1) EcR none sp   16496002
Cell size and cell-cycle regulation (1) EcR none sp   16496002
Dendrite pattern formation EcR Decreased arborization np   16547170
C. trachomatis infection EcR C. trachomatis infection down np   18369471
Muscle morphogenesis and function (1) EcR Lethal np   20220848
Muscle morphogenesis and function (1) EcR Lethal np   20220848
Heat nociception (1) EcR none -1.17   21074052
Heat nociception (1) EcR none -1.17   21074052
Heart development and function (1) EcR none 1   20371351
Heart development and function (2) EcR Decreased viability 4.43   20371351
Serratia marcescens infection (1) EcR none 0.233333333333333   19520911
Notch pathway regulation (4) EcR Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) EcR Completely lethal (before pupal) sp   19363474
Notch pathway regulation (1) EcR Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) EcR none np C96-GAL4 20493818
Notch pathway regulation (2) EcR Lethal strong en-GAL4 20493818
Notch pathway regulation (2) EcR Lethal very strong en-GAL4 20493818
Notch pathway regulation (2) EcR none np C96-GAL4 20493818
Notch pathway regulation (3) EcR Only lethal with Notch np   20493818
Adiposity regulation (1) EcR none 0.237   20074523
Blood cell homeostasis regulation (1) EcR Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) EcR none np   20540764
Blood cell homeostasis regulation (3) EcR none 3.7   20540764
Blood cell homeostasis regulation (4) EcR none 0   20540764
Blood cell homeostasis regulation (5) EcR none 0   20540764
Hippo pathway regulation EcR Downregulation of Hippo pathway 3.97   23263283

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