Genomics
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16 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0286415 | RpS3[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286416 | RpS3[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0245681 | RpS3[JF01410] | Drosophila melanogaster | |
| FBal0038901 | RpS3[Plac92] | hypomorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0089551 | RpS3[prv11] | Drosophila melanogaster | |
| FBal0089550 | RpS3[prv9] | Drosophila melanogaster | |
| FBal0048877 | RpS3[unspecified] | Drosophila melanogaster | |
| FBal0038902 | RpS3[Plac92rv4] | Drosophila melanogaster | |
| FBal0011951 | RpS3[2] | Drosophila melanogaster | |
| FBal0011954 | RpS3[5] | Drosophila melanogaster | |
| FBal0011953 | RpS3[4] | Drosophila melanogaster | |
| FBal0011952 | RpS3[3] | Drosophila melanogaster | |
| FBal0011950 | RpS3[1] | Drosophila melanogaster | |
| FBal0262798 | RpS3[GL00332] | Drosophila melanogaster | |
| FBal0208386 | RpS3[GD4577] | Drosophila melanogaster | |
| FBal0236033 | RpS3[KK109080] | Drosophila melanogaster |
1426 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0084410-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0084410-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- Cleavage of Growing Transcript in the Termination Region,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Transcription,
- RNA Polymerase II Transcription Initiation,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Recycling of eIF2:GDP,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Formation of the Early Elongation Complex,
- Ribosomal scanning and start codon recognition,
- SLBP independent Processing of Histone Pre-mRNAs,
- Metabolism of mRNA,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Formation of RNA Pol II elongation complex,
- Eukaryotic Translation Elongation,
- Transport of the SLBP independent Mature mRNA,
- Elongation arrest and recovery,
- Formation of a pool of free 40S subunits,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Gene Expression,
- RNA Polymerase II Pre-transcription Events,
- Translation initiation complex formation,
- Metabolism of RNA,
- Post-Elongation Processing of the Transcript,
- Transport of Mature Transcript to Cytoplasm,
- Metabolism of proteins,
- SRP-dependent cotranslational protein targeting to membrane,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- mRNA Capping,
- RNA Polymerase II Transcription Elongation,
- RNA Polymerase II Promoter Escape,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Processing of Intronless Pre-mRNAs,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Transcription,
- Cap-dependent Translation Initiation,
- RNA Polymerase II Transcription Termination,
- Processing of Capped Intron-Containing Pre-mRNA,
- Processing of Capped Intronless Pre-mRNA,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Eukaryotic Translation Termination,
- Transport of the SLBP Dependant Mature mRNA,
- Translation,
- Peptide chain elongation,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- 3' -UTR-mediated translational regulation,
- mRNA Processing,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Eukaryotic Translation Initiation,
- Nonsense-Mediated Decay,
- RNA Polymerase II Transcription Initiation And Promoter Clearance
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 42761 | NCBI Entrez Gene identifiers | FBgn0002622 |
| 67703 | BioGRID | FBgn0002622 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
35 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS3 | none | -1.917684667 | 19067489 | |
| Lipid storage | RpS3 | none | 2.327178166 | 19067489 | |
| Drosophila C virus infection | RpS3 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpS3 | Binucleate cells with decreased viability | weak | 15547975 | |
| Alternative splicing | RpS3 | none | sp | 15492211 | |
| Intracellular Listeria monocytogenes infection | RpS3 | Increased GFP protein expression | moderate | 16020693 | |
| Drosophila C virus infection | RpS3 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS3 | Decreased Hedgehog reporter activity | -3.14 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS3 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS3 | Increased G1 cell size, decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpS3 | Decreased viability | 0.715 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpS3 | none | 427 | 16496002 | |
| Candida albicans phagocytosis (1) | RpS3 | none | np | 16336044 | |
| Influenza replication | RpS3 | Decreased Influenza replication | -2.91/-2.86 | 18615016 | |
| Lipid storage | RpS3 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Microtubule assembly and organization | RpS3 | Decreased centrosome number | np | 18463163 | |
| Combinatorial effect with methyl methanesulphonate (2) | RpS3 | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Muscle morphogenesis and function (1) | RpS3 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS3 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS3 | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpS3 | Split myofibril, fading Z-line | np | 20220848 | |
| Heat nociception (1) | RpS3 | none | -0.79 | 21074052 | |
| Heart development and function (1) | RpS3 | Larval lethal | 0.14 | 20371351 | |
| Serratia marcescens infection (1) | RpS3 | none | -0.177215189873417 | 19520911 | |
| Notch pathway regulation (4) | RpS3 | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS3 | Completely lethal (pupal) | sp | 19363474 | |
| Hh pathway regulation | RpS3 | Downregulation of Hh pathway | -0.574476872128138 | 17903264 | |
| Hh pathway regulation | RpS3 | Downregulation of Hh pathway | -0.506105005678134 | 17903264 | |
| Adiposity regulation (1) | RpS3 | none | 0.634 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS3 | Decreased ERK phosphorylation after EGF stimulation | -3.47 | 10 minutes EGF stimulation | 22028469 |
