Genomics
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27 Alleles
31 Clones
4 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0003416:1 | sl:1 |
| FBgn0003416:2 | sl:2 |
| FBgn0003416:3 | sl:3 |
| FBgn0003416:4 | sl:4 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0074230-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0074230-3-prime-utr | Drosophila melanogaster |
Other
68 Pathways
- TCR signaling,
- Inositol phosphate metabolism,
- Platelet activation, signaling and aggregation,
- Signaling by SCF-KIT,
- Metabolism of lipids and lipoproteins,
- Signaling by FGFR,
- GAB1 signalosome,
- Hemostasis,
- PI3K events in ERBB2 signaling,
- FGFR3b ligand binding and activation,
- Immune System,
- Signaling by NGF,
- PLCG1 events in ERBB2 signaling,
- FGFR3c ligand binding and activation,
- Signaling by EGFR,
- FGFR1c ligand binding and activation,
- DAG and IP3 signaling,
- PI3K events in ERBB4 signaling,
- Synthesis of IP3 and IP4 in the cytosol,
- Signaling by FGFR1 mutants,
- Metabolism,
- Phospholipase C-mediated cascade,
- PI-3K cascade,
- Developmental Biology,
- Signaling by EGFR in Cancer,
- Signaling by FGFR1 fusion mutants,
- Disease,
- Fcgamma receptor (FCGR) dependent phagocytosis,
- DAP12 interactions,
- PIP3 activates AKT signaling,
- FGFR2c ligand binding and activation,
- PLC-mediated hydrolysis of PIP2,
- PI3K/AKT activation,
- Downstream signaling of activated FGFR,
- Signaling by constitutively active EGFR,
- Negative regulation of the PI3K/AKT network,
- Role of second messengers in netrin-1 signaling,
- FGFR ligand binding and activation,
- Signaling Pathways,
- B Cell Activation,
- DAP12 signaling,
- Phospholipid metabolism,
- NGF signalling via TRKA from the plasma membrane,
- Fc epsilon receptor (FCERI) signaling,
- GPVI-mediated activation cascade,
- Adaptive Immune System,
- EGFR interacts with phospholipase C-gamma,
- Netrin-1 signaling,
- FGFR2 ligand binding and activation,
- Synthesis of PIPs at the plasma membrane,
- Signaling by PDGF,
- FGFR3 ligand binding and activation,
- Axon guidance,
- Signaling by ERBB2,
- Generation of second messenger molecules,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- FGFR1 ligand binding and activation,
- Innate Immune System,
- PI Metabolism,
- PI3K/AKT Signaling in Cancer,
- Downstream signal transduction,
- Role of phospholipids in phagocytosis,
- PLC-gamma1 signalling,
- Signaling by FGFR mutants,
- Role of LAT2/NTAL/LAB on calcium mobilization,
- Signaling by FGFR in disease,
- Signaling by ERBB4,
- FGFR4 ligand binding and activation
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32601 | NCBI Entrez Gene identifiers | FBgn0003416 |
| 58941 | BioGRID | FBgn0003416 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
33 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | sl | none | 1.210139828 | 19067489 | |
| Lipid storage | sl | none | -0.038582784 | 19067489 | |
| Lipid storage | sl | none | 0.058345123 | 19067489 | |
| Lipid storage | sl | none | -0.166299132 | 19067489 | |
| Lipid storage | sl | none | 1.220895971 | 19067489 | |
| Lipid storage | sl | none | 0.21206495 | 19067489 | |
| ERK signaling | sl | ERK activation reduced | weak | 17086199 | |
| Cell size and cell-cycle regulation (1) | sl | none | sp | 16496002 | |
| EGFR signaling | sl | Abolished ER retention of cSpitz | np | 15469842 | |
| Muscle morphogenesis and function (1) | sl | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | sl | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | sl | none | np | 20220848 | |
| Heat nociception (1) | sl | none | -1.17 | 21074052 | |
| Heat nociception (1) | sl | none | -1.17 | 21074052 | |
| Heart development and function (1) | sl | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | sl | none | -0.181818181818181 | 19520911 | |
| Notch pathway regulation (4) | sl | none | 0 | 19363474 | |
| Notch pathway regulation (4) | sl | none | 0 | 19363474 | |
| Notch pathway regulation (4) | sl | none | 0 | 19363474 | |
| Adiposity regulation (1) | sl | none | -0.053 | 20074523 | |
| Blood cell homeostasis regulation (1) | sl | Increased melanotic mass formation | np | 20540764 | |
| Blood cell homeostasis regulation (2) | sl | none | np | 20540764 | |
| Blood cell homeostasis regulation (3) | sl | none | 4.2 | 20540764 | |
| Blood cell homeostasis regulation (4) | sl | none | 0 | 20540764 | |
| Blood cell homeostasis regulation (5) | sl | none | 0 | 20540764 | |
| RTK-Ras-ERK pathway regulation (1) | sl | none | 0.72 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | sl | none | -0.43 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | sl | none | 0.76 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | sl | none | -1.03 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | sl | none | -2.19 | 23263283 |
