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Gene : Uba1 D. melanogaster
DB identifier  ? FBgn0023143 Secondary Identifier  ? CG1782
Name  ? Ubiquitin activating enzyme 1 Source  FlyBase
  • synonyms:
  • FBgn0010538,
  • Ubiquitin Activating Enzyme,
  • uba1,
  • ubiquitin activating enzyme 1,
  • UBA-1,
  • ubiquitin-activating enzyme (E1),
  • l(2)03405,
  • FBan0001782,
  • FBgn0010688,
  • FBgn0023143,
  • Uba 1,
  • FBtr0088499,
  • FBgn0010605,
  • CG1782,
  • DmUba1,
  • E1,
  • 2/31,
  • l(2)s3484,
  • l(2)05642
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46 Alleles

DB identifier Symbol Allele Class Organism
FBal0243248 Uba1[LL03617]   Drosophila melanogaster
FBal0181115 Uba1[DG24412]   Drosophila melanogaster
FBal0276906 Uba1[G3534]   Drosophila melanogaster
FBal0119371 Uba1[EP2375]   Drosophila melanogaster
FBal0064745 Uba1[k12102]   Drosophila melanogaster
FBal0064746 Uba1[k07517]   Drosophila melanogaster
FBal0064747 Uba1[k07246]   Drosophila melanogaster
FBal0064748 Uba1[k01016]   Drosophila melanogaster
FBal0064749 Uba1[k00232]   Drosophila melanogaster
FBal0064750 Uba1[k00231]   Drosophila melanogaster
FBal0064751 Uba1[k00203]   Drosophila melanogaster
FBal0064752 Uba1[05809]   Drosophila melanogaster
FBal0152148 Uba1[L46A1]   Drosophila melanogaster
FBal0009310 Uba1[s3484]   Drosophila melanogaster
FBal0008024 Uba1[03405]   Drosophila melanogaster
FBal0008093 Uba1[05642]   Drosophila melanogaster
FBal0123044 Uba1[EP2609]   Drosophila melanogaster
FBal0043427 Uba1[03876]   Drosophila melanogaster
FBal0265020 Uba1[D6]   Drosophila melanogaster
FBal0265021 Uba1[H33]   Drosophila melanogaster
FBal0265022 Uba1[H42]   Drosophila melanogaster
FBal0150575 Uba1[Df]   Drosophila melanogaster
FBal0197418 Uba1[B2]   Drosophila melanogaster
FBal0197410 Uba1[A1]   Drosophila melanogaster
FBal0197417 Uba1[B1]   Drosophila melanogaster
FBal0197411 Uba1[A2]   Drosophila melanogaster
FBal0197412 Uba1[A3]   Drosophila melanogaster
FBal0197413 Uba1[A4]   Drosophila melanogaster
FBal0197414 Uba1[A5]   Drosophila melanogaster
FBal0197415 Uba1[A6]   Drosophila melanogaster

187 Clones

Secondary Identifier DB identifier
AT26872 FBcl0039683
AT08148 FBcl0039691
AT21141 FBcl0039693
AT26082 FBcl0039695
bs26f11 FBcl0056569
EC35022 FBcl0071911
EP21511 FBcl0087753
EN06151 FBcl0100885
EN08406 FBcl0100893
EN17828 FBcl0100901
EN08115 FBcl0100903
EK264201 FBcl0131236
EK154407 FBcl0131242
EK308634 FBcl0131454
EK170252 FBcl0131554
EK040440 FBcl0131562
EK180037 FBcl0131602
EK305417 FBcl0131608
EK069736 FBcl0131614
EK169912 FBcl0131622
EK044242 FBcl0131628
EK154209 FBcl0131634
EK266130 FBcl0131640
EK106306 FBcl0131682
EK167013 FBcl0131690
EK208624 FBcl0131696
EK154027 FBcl0131702
EK134138 FBcl0131708
GH24511 FBcl0132945
GH10781 FBcl0133003

4 Exons

DB identifier Symbol
FBgn0023143:4 Uba1:4
FBgn0023143:3 Uba1:3
FBgn0023143:2 Uba1:2
FBgn0023143:1 Uba1:1

2 Transcripts

DB identifier Gene
FBtr0088499 Uba1
FBtr0339517 Uba1

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088499-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339517-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088499-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339517-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
35998 NCBI Entrez Gene identifiers FBgn0023143
61829 BioGRID FBgn0023143

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 4635.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4689.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3340.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 5568.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5000.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2631.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4556.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4379.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2302.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 4415.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3404.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2784.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3262.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4967.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3931.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3764.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3907.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4596.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 4430.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3773.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5590.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 6001.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 4081.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3512.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 5339.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5935.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1737.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2311.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1840.0
FBgn0023143 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1909.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0023143:4_FBgn0023143:3 Drosophila melanogaster
intron_FBgn0023143:3_FBgn0023143:2 Drosophila melanogaster
intron_FBgn0023143:2_FBgn0023143:1 Drosophila melanogaster

10 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Uba1 Decreased lipid droplet area -2.501961696   19067489
Lipid storage Uba1 Decreased lipid droplet area -1.713819204   19067489
Cell size and cell-cycle regulation (1) Uba1 none sp   16496002
Notch pathway regulation (1) Uba1 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Uba1 Lethal very weak or wing-to-wing variations en-GAL4 20493818
Notch pathway regulation (2) Uba1 none np C96-GAL4 20493818
S2 cell spreading Uba1 none np   21041442
Hippo pathway regulation Uba1 none 0.45   23263283
Glycosylation regulation (1) Uba1 none sp   21203496
Huntingtin (Htt) aggregates formation Uba1 Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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