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Gene : 14-3-3zeta D. melanogaster

DB identifier  ? FBgn0004907 Secondary Identifier  ? CG17870
Name  ? 14-3-3zeta Source  FlyBase
  • synonyms:
  • unnamed,
  • 549,
  • FBgn0023038,
  • 2G1,
  • FBgn0010635,
  • Complementation group K,
  • FBgn0046306,
  • FBan0017870,
  • LEONARDO,
  • FBgn0019723,
  • PAR5,
  • D14-3-3zeta,
  • 14-3-3ZETA,
  • D14-3-3,
  • BEST:GH05075,
  • FBgn0004907,
  • 4-3-3 zeta,
  • Leonardo-13-3-3,
  • 14-3-3,
  • 14-3-3 zeta,
  • PAR-5,
  • 5.11,
  • 14-3-3leo,
  • 14-3-3-zeta,
  • LEO,
  • l(2)46CFe,
  • FBgn0064146,
  • D14 3 3 protein,
  • l(2)46Ee,
  • l(2)07103,
  • leonardo 14-3-3,
  • CG17870,
  • K

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56 Alleles

DB identifier Symbol Allele Class Organism
FBal0244971 14-3-3zeta[VDRC.cUa]   Drosophila melanogaster
FBal0244972 14-3-3zeta[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0246788 14-3-3zeta[WW.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0246789 14-3-3zeta[MW.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0246790 14-3-3zeta[WM.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0246791 14-3-3zeta[MM.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0284285 14-3-3zeta[G7590] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0245305 14-3-3zeta[HM04002]   Drosophila melanogaster
FBal0008125 14-3-3zeta[07103] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0059628 14-3-3zeta[P1375]   Drosophila melanogaster
FBal0059629 14-3-3zeta[P1188] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0059630 14-3-3zeta[P1.3H]   Drosophila melanogaster
FBal0162866 14-3-3zeta[EY06147]   Drosophila melanogaster
FBal0157546 14-3-3zeta[EY03325]   Drosophila melanogaster
FBal0059632 14-3-3zeta[7B]   Drosophila melanogaster
FBal0134434 14-3-3zeta[P2335]   Drosophila melanogaster
FBal0137676 14-3-3zeta[KG02642]   Drosophila melanogaster
FBal0278762 14-3-3zeta[GL01310]   Drosophila melanogaster
FBal0062284 14-3-3zeta[tKa]   Drosophila melanogaster
FBal0062285 14-3-3zeta[sev.PK]   Drosophila melanogaster
FBal0062287 14-3-3zeta[a.sev]   Drosophila melanogaster
FBal0065577 14-3-3zeta[12BL] loss of function allele Drosophila melanogaster
FBal0083669 14-3-3zeta[hs.PL]   Drosophila melanogaster
FBal0083670 14-3-3zeta[hbNRE.RpII15]   Drosophila melanogaster
FBal0062286 14-3-3zeta[arm.PK]   Drosophila melanogaster
FBal0134435 14-3-3zeta[LII.2.hs]   Drosophila melanogaster
FBal0134436 14-3-3zeta[LI.15.hs]   Drosophila melanogaster
FBal0065576 14-3-3zeta[7BL] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0157547 14-3-3zeta[5-11]   Drosophila melanogaster
FBal0059631 14-3-3zeta[9.8]   Drosophila melanogaster

625 Clones

Secondary Identifier DB identifier
FGC021G06 FBcl0385718
AT30422 FBcl0039591
bs27a03 FBcl0056513
EC34763 FBcl0071827
EC32729 FBcl0071855
EK291244 FBcl0085006
EK241634 FBcl0085550
EK184863 FBcl0085986
EK073136 FBcl0086002
EK073152 FBcl0086302
EK050809 FBcl0086320
EK068861 FBcl0086338
EK102103 FBcl0086356
EK264764 FBcl0086376
EK072937 FBcl0086390
EK257237 FBcl0086412
EK301861 FBcl0086426
EK212663 FBcl0086848
EK259747 FBcl0086962
EK265356 FBcl0087208
EK098126 FBcl0087320
EK104529 FBcl0087348
EK096040 FBcl0087404
EP00814 FBcl0087593
EP10164 FBcl0087599
EP04048 FBcl0087603
EP11016 FBcl0087633
EP10732 FBcl0087679
EP09256 FBcl0087689
EK303948 FBcl0088024

16 Exons

DB identifier Symbol
FBgn0004907:3 14-3-3zeta:3
FBgn0004907:7 14-3-3zeta:7
FBgn0004907:8 14-3-3zeta:8
FBgn0004907:9 14-3-3zeta:9
FBgn0004907:10 14-3-3zeta:10
FBgn0004907:11 14-3-3zeta:11
FBgn0004907:16 14-3-3zeta:16
FBgn0004907:2 14-3-3zeta:2
FBgn0004907:12 14-3-3zeta:12
FBgn0004907:1 14-3-3zeta:1
FBgn0004907:13 14-3-3zeta:13
FBgn0004907:15 14-3-3zeta:15
FBgn0004907:4 14-3-3zeta:4
FBgn0004907:14 14-3-3zeta:14
FBgn0004907:5 14-3-3zeta:5
FBgn0004907:6 14-3-3zeta:6

12 Transcripts

DB identifier Gene
FBtr0088419 14-3-3zeta
FBtr0088414 14-3-3zeta
FBtr0088413 14-3-3zeta
FBtr0100183 14-3-3zeta
FBtr0100182 14-3-3zeta
FBtr0088418 14-3-3zeta
FBtr0088416 14-3-3zeta
FBtr0088412 14-3-3zeta
FBtr0332916 14-3-3zeta
FBtr0332917 14-3-3zeta
FBtr0088417 14-3-3zeta
FBtr0088415 14-3-3zeta

24 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088414-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088415-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088412-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088416-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088418-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088419-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088417-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088413-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100182-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100183-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332916-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332917-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088414-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088415-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088412-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088416-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088418-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088419-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088417-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088413-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100182-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100183-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332916-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332917-3-prime-utr Drosophila melanogaster

Interactions

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Other

73 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36059 NCBI Entrez Gene identifiers FBgn0004907
61887 BioGRID FBgn0004907

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 8051.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 9110.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 6906.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 6681.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 6935.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 8485.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4570.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4338.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 7523.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 6718.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 5759.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 6172.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 7303.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 8723.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 8315.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 5923.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 7188.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 5499.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 7347.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 7665.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 6815.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 10452.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 6121.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 5649.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 6107.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6124.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5457.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 4189.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 6081.0
FBgn0004907 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 6704.0

19 Introns

DB identifier
Organism . Name
intron_FBgn0004907:3_FBgn0004907:7 Drosophila melanogaster
intron_FBgn0004907:7_FBgn0004907:8 Drosophila melanogaster
intron_FBgn0004907:8_FBgn0004907:9 Drosophila melanogaster
intron_FBgn0004907:9_FBgn0004907:10 Drosophila melanogaster
intron_FBgn0004907:10_FBgn0004907:11 Drosophila melanogaster
intron_FBgn0004907:11_FBgn0004907:16 Drosophila melanogaster
intron_FBgn0004907:2_FBgn0004907:7 Drosophila melanogaster
intron_FBgn0004907:10_FBgn0004907:12 Drosophila melanogaster
intron_FBgn0004907:12_FBgn0004907:16 Drosophila melanogaster
intron_FBgn0004907:1_FBgn0004907:7 Drosophila melanogaster
intron_FBgn0004907:10_FBgn0004907:13 Drosophila melanogaster
intron_FBgn0004907:13_FBgn0004907:15 Drosophila melanogaster
intron_FBgn0004907:13_FBgn0004907:16 Drosophila melanogaster
intron_FBgn0004907:4_FBgn0004907:7 Drosophila melanogaster
intron_FBgn0004907:12_FBgn0004907:15 Drosophila melanogaster
intron_FBgn0004907:12_FBgn0004907:14 Drosophila melanogaster
intron_FBgn0004907:11_FBgn0004907:15 Drosophila melanogaster
intron_FBgn0004907:5_FBgn0004907:7 Drosophila melanogaster
intron_FBgn0004907:6_FBgn0004907:7 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage 14-3-3zeta none -1.818643279   19067489
Lipid storage 14-3-3zeta none -0.018250916   19067489
ERK signaling 14-3-3zeta ERK activation reduced strong   17086199
Cell size and cell-cycle regulation (1) 14-3-3zeta none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) 14-3-3zeta none sp   19543366
Heat nociception (1) 14-3-3zeta none 0.81   21074052
Heart development and function (1) 14-3-3zeta none 1   20371351
Serratia marcescens infection (1) 14-3-3zeta none -0.239130434782608   19520911
Notch pathway regulation (4) 14-3-3zeta none 0   19363474
Notch pathway regulation (1) 14-3-3zeta Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) 14-3-3zeta none np en-GAL4 20493818
Notch pathway regulation (2) 14-3-3zeta none np en-GAL4 20493818
Notch pathway regulation (3) 14-3-3zeta Upregulation of Notch pathway np   20493818
Adiposity regulation (1) 14-3-3zeta none 0.57   20074523
Vaccinia virus infection 14-3-3zeta none sp   20585561
RTK-Ras-ERK pathway regulation (1) 14-3-3zeta none 0.5 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) 14-3-3zeta none 0.14 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) 14-3-3zeta none -0.46 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) 14-3-3zeta none -0.14 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation 14-3-3zeta none 0.62   23263283
Glycosylation regulation (1) 14-3-3zeta none sp   21203496

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