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Gene : eIF-3p66 D. melanogaster

DB identifier  ? FBgn0040227 Secondary Identifier  ? CG10161
Name  ? Eukaryotic initiation factor 3 p66 subunit Source  FlyBase
  • synonyms:
  • eIF3-S7,
  • FBgn0026594,
  • CG10161,
  • FBan0010161,
  • BEST:GM10514,
  • FBgn0040227,
  • 153314_at,
  • GM10514,
  • GM04979,
  • eIF-3p66,
  • FBgn0039100,
  • eIF3p66

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0159290 eIF-3p66[EY05735]   Drosophila melanogaster
FBal0270352 eIF-3p66[NIG.10161R]   Drosophila melanogaster
FBal0095869 eIF-3p66[GS3028]   Drosophila melanogaster
FBal0287357 eIF-3p66[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287358 eIF-3p66[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0214938 eIF-3p66[GD6702]   Drosophila melanogaster
FBal0288060 eIF-3p66[EP-654a]   Drosophila melanogaster

204 Clones

Secondary Identifier DB identifier
EC27103 FBcl0062361
EC38803 FBcl0062369
EN05123 FBcl0091969
EN14943 FBcl0091995
GH13209 FBcl0118961
GH10787 FBcl0120543
GH24312 FBcl0121345
EK199922 FBcl0122886
EK222143 FBcl0122920
EK096031 FBcl0122992
EK107410 FBcl0123002
EK152410 FBcl0123260
EK175902 FBcl0123530
EK021537 FBcl0123542
EK167622 FBcl0123680
EK007842 FBcl0123752
EK164945 FBcl0123850
GM10514 FBcl0138341
GM04979 FBcl0138345
GM06263 FBcl0138351
GM10735 FBcl0142447
GM28010 FBcl0144396
GM15305 FBcl0144398
GM20125 FBcl0144401
GM18650 FBcl0144402
GM13889 FBcl0144413
GM29092 FBcl0147106
LD07910 FBcl0156380
LD08777 FBcl0156502
LD09715 FBcl0156849

4 Exons

DB identifier Symbol
FBgn0040227:1 eIF-3p66:1
FBgn0040227:2 eIF-3p66:2
FBgn0040227:3 eIF-3p66:3
FBgn0040227:4 eIF-3p66:4

1 Transcripts

DB identifier Gene
FBtr0089622 eIF-3p66

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089622-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089622-3-prime-utr Drosophila melanogaster

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43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42789 NCBI Entrez Gene identifiers FBgn0040227
67727 BioGRID FBgn0040227

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 6357.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 6467.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 4852.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 7998.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 7421.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 5698.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 5082.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 6132.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3443.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 5151.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 5965.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 5054.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4739.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 5711.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 6056.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 6701.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 4904.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4923.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6495.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 5655.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5980.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 5092.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 4590.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3828.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4330.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6824.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 6214.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 7045.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 4888.0
FBgn0040227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 5322.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0040227:1_FBgn0040227:2 Drosophila melanogaster
intron_FBgn0040227:2_FBgn0040227:3 Drosophila melanogaster
intron_FBgn0040227:3_FBgn0040227:4 Drosophila melanogaster

23 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eIF-3p66 none 0.057542597   19067489
Lipid storage eIF-3p66 none -0.629391353   19067489
Cytokinesis regulation eIF-3p66 Binucleate cells weak   15547975
Cell size and cell-cycle regulation (1) eIF-3p66 Increased G1 DNA content, increased G1 cell size sp   16496002
Cell size and cell-cycle regulation (1) eIF-3p66 Increased G1 DNA content, increased G1 cell size sp   16496002
Cell size and cell-cycle regulation (2) eIF-3p66 none 0.963   16496002
Cell size and cell-cycle regulation (2) eIF-3p66 none 1.337   16496002
Cell size and cell-cycle regulation (3) eIF-3p66 Decreased cell number 413   16496002
Cell size and cell-cycle regulation (3) eIF-3p66 none 423   16496002
C. trachomatis infection eIF-3p66 C. trachomatis infection up np   18369471
Influenza replication eIF-3p66 Decreased Influenza replication -1.61/-2.83   18615016
Mitochondrial biogenesis and function eIF-3p66 Increased mitochondrial citrate synthase activity, decreased viability 2.016   18042644
Microtubule assembly and organization eIF-3p66 none np   18463163
Mutant human huntingtin aggregation eIF-3p66 Decreased mutant human huntingtin aggregation <= -2   19789644
Notch pathway regulation (1) eIF-3p66 Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) eIF-3p66 none np en-GAL4 20493818
Notch pathway regulation (3) eIF-3p66 Only lethal with Notch np   20493818
RTK-Ras-ERK pathway regulation (1) eIF-3p66 Increased ERK phosphorylation after EGF stimulation 1.51 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eIF-3p66 none -0.37 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF-3p66 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.53 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF-3p66 Increased ERK phosphorylation after sSpitz and EGF stimulation 3.98 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation eIF-3p66 none -1.23   23263283
Glycosylation regulation (1) eIF-3p66 none sp   21203496

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