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Gene : Ddc D. melanogaster

DB identifier  ? FBgn0000422 Secondary Identifier  ? CG10697
Name  ? Dopa decarboxylase Source  FlyBase
  • synonyms:
  • FBgn0000422,
  • CG10697,
  • FBgn0022245,
  • 5-HT,
  • l(2)k02104,
  • unnamed,
  • AADC,
  • DDC,
  • Dopadecarboxylase,
  • l(2)37Bl,
  • FBan0010697,
  • fDDC,
  • DdcDm,
  • DOPA decarboxylase,
  • l(2)37Ch,
  • 3,4-Dihydroxyphenylalanine decarboxylase,
  • dopamine decarboxylase,
  • aromatic L-amino acid decarboxylase,
  • dopa-decarboxylase,
  • transcription unit No. 3

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145 Alleles

DB identifier Symbol Allele Class Organism
FBal0277328 Ddc[dsRNA.Scer\UAS.WIZ]   Drosophila melanogaster
FBal0277329 Ddc[dsRNA.Scer\UAS.Sym]   Drosophila melanogaster
FBal0220720 Ddc[JF02356]   Drosophila melanogaster
FBal0258743 Ddc[KK100293]   Drosophila melanogaster
FBal0184172 Ddc[c06496]   Drosophila melanogaster
FBal0184171 Ddc[e00927]   Drosophila melanogaster
FBal0064592 Ddc[k02104]   Drosophila melanogaster
FBal0277750 Ddc[HL7.T:Scer\GAL4]   Drosophila melanogaster
FBal0002251 Ddc[2] amorphic allele - genetic evidence Drosophila melanogaster
FBal0184184 Ddc[R11]   Drosophila melanogaster
FBal0002294 Ddc[DE1]   Drosophila melanogaster
FBal0038711 Ddc[+t7.5]   Drosophila melanogaster
FBal0038713 Ddc[Adh.-1320-69]   Drosophila melanogaster
FBal0033591 Ddc[+4.tCa]   Drosophila melanogaster
FBal0033589 Ddc[Delta-208,-38]   Drosophila melanogaster
FBal0033590 Ddc[Delta-208,-60]   Drosophila melanogaster
FBal0033593 Ddc[I-38]   Drosophila melanogaster
FBal0033595 Ddc[I-60]   Drosophila melanogaster
FBal0033594 Ddc[I-38.Inv]   Drosophila melanogaster
FBal0033596 Ddc[I-60.Inv]   Drosophila melanogaster
FBal0033597 Ddc[Im1]   Drosophila melanogaster
FBal0033598 Ddc[Im2]   Drosophila melanogaster
FBal0029304 Ddc[EN5'Delta47]   Drosophila melanogaster
FBal0029300 Ddc[EN5'Delta199]   Drosophila melanogaster
FBal0029301 Ddc[EN5'Delta259]   Drosophila melanogaster
FBal0029302 Ddc[EN5'Delta395]   Drosophila melanogaster
FBal0029303 Ddc[EN5'Delta435]   Drosophila melanogaster
FBal0029299 Ddc[EN3'Delta87]   Drosophila melanogaster
FBal0029297 Ddc[EN3'Delta259]   Drosophila melanogaster
FBal0029298 Ddc[EN3'Delta371]   Drosophila melanogaster

64 Clones

Secondary Identifier DB identifier
ESG0118c.B21_B11 FBcl0002659
ESG0118b.B21_A06 FBcl0003059
ESG0110b.E21_F07 FBcl0003971
ESG0114a.B21_E11 FBcl0007083
ESG013a.E21.1_A04 FBcl0008605
EK229621 FBcl0035078
EK229159 FBcl0032546
EK186205 FBcl0032564
EK109020 FBcl0032620
EK273411 FBcl0032656
EK159613 FBcl0032694
EK046462 FBcl0032726
EK236631 FBcl0032744
EK125508 FBcl0032764
EK157311 FBcl0032780
EP02457 FBcl0079411
EP14551 FBcl0079461
GH06162 FBcl0113513
GH13180 FBcl0113575
GH12804 FBcl0113577
GH04133 FBcl0113579
GH15243 FBcl0113607
GH14812 FBcl0113611
GH06280 FBcl0117075
GH11377 FBcl0117115
GH03631 FBcl0117161
GH08354 FBcl0117239
HL06075 FBcl0149305
LP11638 FBcl0184693
LP07190 FBcl0184721

5 Exons

DB identifier Symbol
FBgn0000422:5 Ddc:5
FBgn0000422:2 Ddc:2
FBgn0000422:1 Ddc:1
FBgn0000422:4 Ddc:4
FBgn0000422:3 Ddc:3

3 Transcripts

DB identifier Gene
FBtr0081167 Ddc
FBtr0081166 Ddc
FBtr0290291 Ddc

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0081166-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081167-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0290291-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081166-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081167-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0290291-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35190 NCBI Entrez Gene identifiers FBgn0000422
61175 BioGRID FBgn0000422

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 135.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 81.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 145.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 108.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 136.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 252.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 171.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 14.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 92.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 189.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 59.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 6.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 82.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 127.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 48.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 27.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 111.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 170.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 66.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 183.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 95.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 237.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 183.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 327.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 207.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 67.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 134.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 77.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 110.0
FBgn0000422 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 66.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0000422:5_FBgn0000422:4 Drosophila melanogaster
intron_FBgn0000422:4_FBgn0000422:2 Drosophila melanogaster
intron_FBgn0000422:2_FBgn0000422:1 Drosophila melanogaster
intron_FBgn0000422:3_FBgn0000422:1 Drosophila melanogaster
intron_FBgn0000422:5_FBgn0000422:2 Drosophila melanogaster

17 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Ddc none -1.290287585   19067489
Lipid storage Ddc none -1.080907288   19067489
Cell size and cell-cycle regulation (1) Ddc none sp   16496002
Heat nociception (1) Ddc none 0.12   21074052
Heat nociception (1) Ddc none -1.17   21074052
Heart development and function (1) Ddc none 1   20371351
Heart development and function (2) Ddc Decreased viability 3.55   20371351
Serratia marcescens infection (1) Ddc none -0.397260273972602   19520911
Notch pathway regulation (4) Ddc Colour defects 8   19363474
Notch pathway regulation (4) Ddc Colour defects, bristle morphology defects sp   19363474
Blood cell homeostasis regulation (1) Ddc Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Ddc Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) Ddc none 1   20540764
Blood cell homeostasis regulation (4) Ddc none 0   20540764
Blood cell homeostasis regulation (5) Ddc none 0   20540764
Hippo pathway regulation Ddc none 1.35   23263283
Glycosylation regulation (1) Ddc Decreased Chp protein expression np   21203496

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