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Gene : Pka-C3 D. melanogaster
DB identifier  ? FBgn0000489 Secondary Identifier  ? CG6117
Name  ? cAMP-dependent protein kinase 3 Source  FlyBase
  • synonyms:
  • FBgn0004631,
  • Pk72A,
  • Pk?5,
  • Protein-kinase-like-72A,
  • FBan0006117,
  • PKA-C3,
  • CG6117,
  • PKA C3,
  • PKA-C-3,
  • Dpck,
  • PKA,
  • cAMP-dependent protein kinase,
  • Swiss Cheese,
  • FBgn0000489,
  • cAMP-activated protein kinase A,
  • 5-23,
  • DC2
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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0266925 Pka-C3[MI04599]   Drosophila melanogaster
FBal0276655 Pka-C3[MI04507]   Drosophila melanogaster
FBal0156074 Pka-C3[EY02687]   Drosophila melanogaster
FBal0182254 Pka-C3[f06761]   Drosophila melanogaster
FBal0182255 Pka-C3[f00695]   Drosophila melanogaster
FBal0160017 Pka-C3[EY03065]   Drosophila melanogaster
FBal0156073 Pka-C3[KG00222]   Drosophila melanogaster
FBal0033963 Pka-C3[Pka-C1.PM]   Drosophila melanogaster
FBal0242308 Pka-C3[JF02723]   Drosophila melanogaster
FBal0279083 Pka-C3[HMS01970]   Drosophila melanogaster
FBal0214689 Pka-C3[GD11825]   Drosophila melanogaster
FBal0274978 Pka-C3[NIG.6117R]   Drosophila melanogaster

39 Clones

Secondary Identifier DB identifier
ESG013a.E21.1_H09 FBcl0012445
AT02564 FBcl0014385
AT07350 FBcl0014519
AT26308 FBcl0014523
AT20151 FBcl0014529
AT31652 FBcl0014533
AT10577 FBcl0014569
EK261529 FBcl0051578
EK216813 FBcl0051584
EK195502 FBcl0051594
EK171327 FBcl0051626
EK206844 FBcl0051708
EK174002 FBcl0051732
EK203715 FBcl0052580
EK271504 FBcl0052584
CK02216 FBcl0058921
EK304364 FBcl0062440
EK205033 FBcl0065352
EK183856 FBcl0065494
EP19847 FBcl0087755
GH13608 FBcl0106703
RH13709 FBcl0243105
RH69793 FBcl0243109
RH29690 FBcl0243220
RH51995 FBcl0243268
RH42543 FBcl0243300
RH66252 FBcl0243373
EC056331 FBcl0303233
CK01.11A.A12 FBcl0425649
EK222762 FBcl0357805

11 Exons

DB identifier Symbol
FBgn0000489:11 Pka-C3:11
FBgn0000489:10 Pka-C3:10
FBgn0000489:8 Pka-C3:8
FBgn0000489:7 Pka-C3:7
FBgn0000489:6 Pka-C3:6
FBgn0000489:5 Pka-C3:5
FBgn0000489:4 Pka-C3:4
FBgn0000489:3 Pka-C3:3
FBgn0000489:2 Pka-C3:2
FBgn0000489:9 Pka-C3:9
FBgn0000489:1 Pka-C3:1

2 Transcripts

DB identifier Gene
FBtr0075528 Pka-C3
FBtr0075529 Pka-C3

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075528-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075529-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075528-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075529-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
39733 NCBI Entrez Gene identifiers FBgn0000489
65045 BioGRID FBgn0000489

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 249.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 241.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 213.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 462.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1400.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 192.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1422.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 141.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 452.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 375.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 130.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 215.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 198.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 121.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 170.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 362.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 210.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 147.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 94.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 117.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 164.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 89.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 197.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 140.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2187.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 221.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 792.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 711.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 302.0
FBgn0000489 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 220.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0000489:9_FBgn0000489:8 Drosophila melanogaster
intron_FBgn0000489:8_FBgn0000489:7 Drosophila melanogaster
intron_FBgn0000489:7_FBgn0000489:6 Drosophila melanogaster
intron_FBgn0000489:6_FBgn0000489:5 Drosophila melanogaster
intron_FBgn0000489:5_FBgn0000489:4 Drosophila melanogaster
intron_FBgn0000489:4_FBgn0000489:3 Drosophila melanogaster
intron_FBgn0000489:3_FBgn0000489:1 Drosophila melanogaster
intron_FBgn0000489:11_FBgn0000489:10 Drosophila melanogaster
intron_FBgn0000489:10_FBgn0000489:8 Drosophila melanogaster
intron_FBgn0000489:3_FBgn0000489:2 Drosophila melanogaster

22 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pka-C3 Decreased lipid droplet area -4.438179262   19067489
Lipid storage Pka-C3 Decreased lipid droplet area -2.026316136   19067489
Lipid storage Pka-C3 none 0.684481643   19067489
Lipid storage Pka-C3 none -0.480502561   19067489
ERK signaling Pka-C3 ERK activation reduced strong   17086199
Cell cycle regulation (1) Pka-C3 none np   15616552
Cell cycle regulation (2) Pka-C3 none np   15616552
Cell size and cell-cycle regulation (1) Pka-C3 none sp   16496002
Cell size and cell-cycle regulation (1) Pka-C3 none sp   16496002
Actin organization and cell morphology (1) Pka-C3 none np   19265526
Actin organization and cell morphology (2) Pka-C3 none np   19265526
Actin organization and cell morphology (3) Pka-C3 none np   19265526
Actin organization and cell morphology (4) Pka-C3 none np   19265526
Actin organization and cell morphology (5) Pka-C3 none np   19265526
Actin organization and cell morphology (6) Pka-C3 none np   19265526
Vaccinia virus infection Pka-C3 none sp   20585561
RTK-Ras-ERK pathway regulation (1) Pka-C3 none 1.31 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Pka-C3 Decreased ERK phosphorylation after EGF stimulation -4.2 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pka-C3 none 0.42 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pka-C3 none 0.61 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Pka-C3 none -1.98   23263283
Glycosylation regulation (1) Pka-C3 none sp   21203496

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