Genomics
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6 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0281114 | RpS10a[GL00728] | Drosophila melanogaster | |
| FBal0287209 | RpS10a[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287210 | RpS10a[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208367 | RpS10a[GD7556] | Drosophila melanogaster | |
| FBal0271192 | RpS10a[NIG.12275R] | Drosophila melanogaster | |
| FBal0233313 | RpS10a[KK105058] | Drosophila melanogaster |
7 Clones
| Secondary Identifier | DB identifier |
|---|---|
| EK024256 | FBcl0015554 |
| EK001001 | FBcl0015676 |
| EK075715 | FBcl0015714 |
| LD32148 | FBcl0178405 |
| CK01.97D.D5 | FBcl0420892 |
| Dmel_neb_014402_0119_3386 | FBcl0370989 |
| CK01.28B.F12 | FBcl0418255 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0085194-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085194-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- SRP-dependent cotranslational protein targeting to membrane,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Termination,
- Translation,
- Translation initiation complex formation,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- RNA Polymerase II Promoter Escape,
- Post-Elongation Processing of the Transcript,
- mRNA Capping,
- Cap-dependent Translation Initiation,
- Gene Expression,
- Processing of Capped Intronless Pre-mRNA,
- Metabolism of proteins,
- mRNA Processing,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Recycling of eIF2:GDP,
- Processing of Capped Intron-Containing Pre-mRNA,
- Eukaryotic Translation Initiation,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Processing of Intronless Pre-mRNAs,
- Peptide chain elongation,
- Cleavage of Growing Transcript in the Termination Region,
- Transcription,
- 3' -UTR-mediated translational regulation,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Formation of a pool of free 40S subunits,
- Ribosomal scanning and start codon recognition,
- Metabolism of RNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Elongation arrest and recovery,
- Transport of the SLBP independent Mature mRNA,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Formation of the ternary complex, and subsequently, the 43S complex,
- RNA Polymerase II Transcription,
- Formation of the Early Elongation Complex,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Eukaryotic Translation Termination,
- Eukaryotic Translation Elongation,
- RNA Polymerase II Transcription Elongation,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Pre-transcription Events,
- Nonsense-Mediated Decay,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- SLBP independent Processing of Histone Pre-mRNAs,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Metabolism of mRNA,
- Formation of RNA Pol II elongation complex,
- Transport of Mature Transcript to Cytoplasm,
- RNA Polymerase II Transcription Initiation,
- Transport of the SLBP Dependant Mature mRNA,
- GTP hydrolysis and joining of the 60S ribosomal subunit
1 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43321 | NCBI Entrez Gene identifiers | FBgn0027494 |
9 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
23 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS10a | none | 0.802794427 | 19067489 | |
| Lipid storage | RpS10a | none | 0 | 19067489 | |
| Cell size and cell-cycle regulation (1) | RpS10a | none | sp | 16496002 | |
| Lipid storage | RpS10a | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS10a | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS10a | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS10a | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Regulated secretory pathway biogenesis (1) | RpS10a | none | -1.4 | 21149569 | |
| Heart development and function (1) | RpS10a | none | 1 | 20371351 | |
| Heart development and function (1) | RpS10a | Embryonic lethal or no offspring | 0.5 | 20371351 | |
| Serratia marcescens infection (1) | RpS10a | none | 1.37096774193548 | 19520911 | |
| Notch pathway regulation (4) | RpS10a | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS10a | Notum malformation death | 10 | 19363474 | |
| Self-renewal and differentiation in neural stem cells | RpS10a | GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal | sp | 21549331 | |
| Self-renewal and differentiation in neural stem cells | RpS10a | Neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underproliferation, lethal | sp | 21549331 | |
| Adiposity regulation (1) | RpS10a | none | -0.423 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS10a | none | 0.5 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS10a | none | 0.44 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS10a | none | 1.31 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS10a | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.61 | 30 minutes sSpitz stimulation | 22028469 |
| Wg pathway regulation (1) | RpS10a | Decreased WgRluc and not changed sFluc protein expression | medium | 21886182 | |
| Hippo pathway regulation | RpS10a | none | -0.91 | 23263283 | |
| Glycosylation regulation (1) | RpS10a | none | sp | 21203496 |
