Genomics
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11 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0263608 | RpL38[GD13653] | Drosophila melanogaster | |
| FBal0268401 | RpL38[dsRNA.WIZ.Scer\UAS] | Drosophila melanogaster | |
| FBal0181800 | RpL38[P3] | Drosophila melanogaster | |
| FBal0181801 | RpL38[KPL1] | Drosophila melanogaster | |
| FBal0181803 | RpL38[2b1] | Drosophila melanogaster | |
| FBal0181802 | RpL38[2b2] | Drosophila melanogaster | |
| FBal0048867 | RpL38[unspecified] | Drosophila melanogaster | |
| FBal0009006 | RpL38[45-72] | loss of function allele | Drosophila melanogaster |
| FBal0150415 | RpL38[NC21] | Drosophila melanogaster | |
| FBal0287028 | RpL38[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287029 | RpL38[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster |
189 Clones
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0334985-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0111120-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0334985-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0111120-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- Formation of a pool of free 40S subunits,
- Processing of Capped Intron-Containing Pre-mRNA,
- Cap-dependent Translation Initiation,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Translation,
- Formation of the Early Elongation Complex,
- RNA Polymerase II Transcription,
- Ribosomal scanning and start codon recognition,
- RNA Polymerase II Pre-transcription Events,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Nonsense-Mediated Decay,
- Transport of the SLBP independent Mature mRNA,
- 3' -UTR-mediated translational regulation,
- mRNA Processing,
- RNA Polymerase II Transcription Elongation,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Metabolism of RNA,
- Cleavage of Growing Transcript in the Termination Region,
- Post-Elongation Processing of Intronless pre-mRNA,
- Gene Expression,
- Metabolism of mRNA,
- Metabolism of proteins,
- Transport of Mature Transcript to Cytoplasm,
- Post-Elongation Processing of the Transcript,
- RNA Polymerase II Transcription Termination,
- Eukaryotic Translation Termination,
- Eukaryotic Translation Elongation,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Formation of RNA Pol II elongation complex,
- Elongation arrest and recovery,
- SRP-dependent cotranslational protein targeting to membrane,
- Transcription,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- RNA Polymerase II Promoter Escape,
- Transport of the SLBP Dependant Mature mRNA,
- Processing of Capped Intronless Pre-mRNA,
- Eukaryotic Translation Initiation,
- RNA Polymerase II Transcription Initiation,
- mRNA Capping,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Processing of Intronless Pre-mRNAs,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Peptide chain elongation,
- Transport of Mature mRNA derived from an Intron-Containing Transcript
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 3355144 | NCBI Entrez Gene identifiers | FBgn0040007 |
| 78269 | BioGRID | FBgn0040007 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
2 Introns
| DB identifier |
Organism . Name |
|---|---|
| intron_FBgn0040007:3_FBgn0040007:2 | Drosophila melanogaster |
| intron_FBgn0040007:3_FBgn0040007:1 | Drosophila melanogaster |
26 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL38 | Increased lipid droplet area | 4.115972571 | 19067489 | |
| Lipid storage | RpL38 | Increased lipid droplet area | 4.935064603 | 19067489 | |
| ERK signaling | RpL38 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpL38 | Drosophila C virus replication down | np | 17040126 | |
| Intracellular Listeria monocytogenes infection | RpL38 | Increased GFP protein expression | strong | 16020693 | |
| Drosophila C virus infection | RpL38 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL38 | Decreased Hedgehog reporter activity | -3.63 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL38 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL38 | Decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL38 | Decreased viability | 0.556 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL38 | Decreased cell number | 405 | 16496002 | |
| Cell size and cell-cycle regulation (4) | RpL38 | Increased number of mitotic cells | 0.9 | 16496002 | |
| Muscle morphogenesis and function (1) | RpL38 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpL38 | none | np | 20220848 | |
| Heat nociception (1) | RpL38 | none | -0.36 | 21074052 | |
| Serratia marcescens infection (1) | RpL38 | none | 0.329896907216494 | 19520911 | |
| Notch pathway regulation (4) | RpL38 | Completely lethal (before pupal) | sp | 19363474 | |
| Hh pathway regulation | RpL38 | Downregulation of Hh pathway | -0.639606576822036 | 17903264 | |
| Hh pathway regulation | RpL38 | Downregulation of Hh pathway | -0.511618636928666 | 17903264 | |
| Notch pathway regulation (1) | RpL38 | Downregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | RpL38 | none | -0.299 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpL38 | none | -0.26 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpL38 | Decreased ERK phosphorylation after EGF stimulation | -4.07 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL38 | none | 0.84 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL38 | none | 1.45 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpL38 | Upregulation of Hippo pathway | -3.05 | 23263283 |
