Genomics
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7 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0220846 | RpS15[G3660] | Drosophila melanogaster | |
| FBal0159868 | RpS15[e01611] | Drosophila melanogaster | |
| FBal0287194 | RpS15[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287195 | RpS15[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208371 | RpS15[GD12521] | Drosophila melanogaster | |
| FBal0235868 | RpS15[KK108851] | Drosophila melanogaster | |
| FBal0275954 | RpS15[NIG.8332R] | Drosophila melanogaster |
658 Clones
6 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0034138:6 | RpS15:6 |
| FBgn0034138:4 | RpS15:4 |
| FBgn0034138:3 | RpS15:3 |
| FBgn0034138:1 | RpS15:1 |
| FBgn0034138:5 | RpS15:5 |
| FBgn0034138:2 | RpS15:2 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0087123-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0087124-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0087123-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0087124-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- SLBP independent Processing of Histone Pre-mRNAs,
- Eukaryotic Translation Elongation,
- Translation,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Formation of RNA Pol II elongation complex,
- Nonsense-Mediated Decay,
- Metabolism of RNA,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- mRNA Capping,
- Cap-dependent Translation Initiation,
- Eukaryotic Translation Initiation,
- Metabolism of proteins,
- Processing of Capped Intron-Containing Pre-mRNA,
- Post-Elongation Processing of the Transcript,
- Ribosomal scanning and start codon recognition,
- Recycling of eIF2:GDP,
- Gene Expression,
- Transport of the SLBP Dependant Mature mRNA,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Translation initiation complex formation,
- RNA Polymerase II Promoter Escape,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Formation of a pool of free 40S subunits,
- Cleavage of Growing Transcript in the Termination Region,
- RNA Polymerase II Transcription Termination,
- Formation of the ternary complex, and subsequently, the 43S complex,
- RNA Polymerase II Pre-transcription Events,
- Processing of Intronless Pre-mRNAs,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Formation of the Early Elongation Complex,
- RNA Polymerase II Transcription,
- mRNA Processing,
- RNA Polymerase II Transcription Elongation,
- Processing of Capped Intronless Pre-mRNA,
- Transport of the SLBP independent Mature mRNA,
- Peptide chain elongation,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- 3' -UTR-mediated translational regulation,
- RNA Polymerase II Transcription Initiation,
- Metabolism of mRNA,
- SRP-dependent cotranslational protein targeting to membrane,
- Eukaryotic Translation Termination,
- Transport of Mature Transcript to Cytoplasm,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Elongation arrest and recovery,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Transcription,
- Post-Elongation Processing of Intronless pre-mRNA
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36851 | NCBI Entrez Gene identifiers | FBgn0034138 |
| 62564 | BioGRID | FBgn0034138 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
5 Introns
30 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS15 | none | 2.405861657 | 19067489 | |
| Lipid storage | RpS15 | none | 1.371103072 | 19067489 | |
| Drosophila C virus infection | RpS15 | Drosophila C virus replication down | np | 17040126 | |
| Intracellular Listeria monocytogenes infection | RpS15 | Increased GFP protein expression | moderate | 16020693 | |
| Drosophila C virus infection | RpS15 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS15 | Decreased Hedgehog reporter activity | -2.84 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS15 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS15 | Increased G1 DNA content, decreased G2 DNA content, decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | RpS15 | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpS15 | none | 1.05 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpS15 | none | 445 | 16496002 | |
| Lipid storage | RpS15 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS15 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS15 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS15 | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpS15 | none | np | 20220848 | |
| Heat nociception (1) | RpS15 | Lethal | 0.88 | 21074052 | |
| Heat nociception (1) | RpS15 | Developmentally lethal | -0.67 | 21074052 | |
| Heart development and function (1) | RpS15 | Larval lethal | 0.15 | 20371351 | |
| Serratia marcescens infection (1) | RpS15 | none | 0.0909090909090909 | 19520911 | |
| Notch pathway regulation (4) | RpS15 | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS15 | Completely lethal (before pupal) | sp | 19363474 | |
| Hh pathway regulation | RpS15 | Downregulation of Hh pathway | -0.462691591682328 | 17903264 | |
| Adiposity regulation (1) | RpS15 | none | 0.354 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS15 | Decreased ERK phosphorylation after EGF stimulation | -2.28 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS15 | Decreased ERK phosphorylation after EGF stimulation | -3.8 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS15 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.9 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS15 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.04 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpS15 | none | -2.9 | 23263283 | |
| Glycosylation regulation (1) | RpS15 | Decreased Chp protein expression | np | 21203496 |
