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Gene : Vps25 D. melanogaster
DB identifier  ? FBgn0022027 Secondary Identifier  ? CG14750
Name  ? Vacuolar protein sorting 25 Source  FlyBase
  • synonyms:
  • ESCRT-II,
  • l(2)k08904,
  • vesicle protein sorting 25,
  • FBan0014750,
  • ESCRT-I,
  • FBgn0033314,
  • lethal (2) 44Db,
  • dVps25,
  • CG14750,
  • l(2)44Db,
  • VPS25,
  • FBgn0022027
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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0263455 Vps25[VDRC.cUa]   Drosophila melanogaster
FBal0220546 Vps25[JF02055]   Drosophila melanogaster
FBal0220427 Vps25[hs.PV]   Drosophila melanogaster
FBal0197867 Vps25[Pb2931]   Drosophila melanogaster
FBal0197871 Vps25[A3] loss of function allele Drosophila melanogaster
FBal0104497 Vps25[4]   Drosophila melanogaster
FBal0104498 Vps25[3]   Drosophila melanogaster
FBal0064311 Vps25[k08904]   Drosophila melanogaster
FBal0104500 Vps25[1]   Drosophila melanogaster
FBal0104499 Vps25[2]   Drosophila melanogaster
FBal0104496 Vps25[5]   Drosophila melanogaster
FBal0232112 Vps25[KK102944]   Drosophila melanogaster
FBal0194621 Vps25[K2] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0194622 Vps25[N55] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0194623 Vps25[Scer\UAS.cHa]   Drosophila melanogaster
FBal0194624 Vps25[hs.PH]   Drosophila melanogaster
FBal0208991 Vps25[GD8432]   Drosophila melanogaster
FBal0271982 Vps25[NIG.14750R]   Drosophila melanogaster

24 Clones

Secondary Identifier DB identifier
DPiM_RH14578 FBcl0741463
EK110549 FBcl0134228
EK283761 FBcl0134252
GM18081 FBcl0146975
RH45103 FBcl0266381
RH16644 FBcl0266722
RH14578 FBcl0266762
Dmel_dig_018313_0592_0737 FBcl0376182
525001 FBcl0441901
RP004538392 FBcl0622951
RP004245311 FBcl0622952
RP004243401 FBcl0622953
RP004261053 FBcl0622954
RP004205413 FBcl0622955
RP004128847 FBcl0622956
RP004141706 FBcl0622957
RP004346366 FBcl0622958
RP004188391 FBcl0622959
RP004266102 FBcl0622960
RP004135435 FBcl0622961
RP004397771 FBcl0622962
14819 FBcl0441849
178491 FBcl0441870
10726 FBcl0441875

2 Exons

DB identifier Symbol
FBgn0022027:1 Vps25:1
FBgn0022027:2 Vps25:2

1 Transcripts

DB identifier Gene
FBtr0088694 Vps25

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088694-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088694-3-prime-utr Drosophila melanogaster

Interactions

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Other

2 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
35847 NCBI Entrez Gene identifiers FBgn0022027
61697 BioGRID FBgn0022027

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 382.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 603.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 248.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 494.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 728.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 419.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 273.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 433.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 385.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 455.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 394.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 109.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 342.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 331.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 318.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 354.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 373.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 210.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 443.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 410.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 271.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 439.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 428.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 413.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 249.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 350.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 369.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 411.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 384.0
FBgn0022027 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 326.0

1 Introns

DB identifier
Organism . Name
intron_FBgn0022027:1_FBgn0022027:2 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Vps25 none 1.788716696   19067489
Lipid storage Vps25 none -0.371056992   19067489
Cell size and cell-cycle regulation (1) Vps25 none sp   16496002
M. smegmatis infection Vps25 No effect on M. smegmatis infection np   18287038
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) Vps25 none 4.09   17267500
Combinatorial effect with methyl methanesulphonate (1) Vps25 Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Vps25 Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) Vps25 Lethal np   20220848
Heat nociception (1) Vps25 Increased noxious heat avoidance 3.76   21074052
Heart development and function (1) Vps25 none 0.75   20371351
Heart development and function (2) Vps25 none 2.63   20371351
Serratia marcescens infection (1) Vps25 none 1.1038961038961   19520911
Notch pathway regulation (4) Vps25 Completely lethal (pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Vps25 GFP aggregates number, GFP aggregates size, lethal sp   21549331
Notch pathway regulation (1) Vps25 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Vps25 Upregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up, broader, ectopic; wing disc myrRFP: accumulation sp en-GAL4 20493818
Notch pathway regulation (2) Vps25 Upregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up, broader, ectopic; wing disc myrRFP: accumulation, reduced sp en-GAL4 20493818
Notch pathway regulation (2) Vps25 Upregulation of Notch pathway; wing pouch: spoon-like, crumbled sp C96-GAL4 20493818
Notch pathway regulation (3) Vps25 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Vps25 none -0.341   20074523
Blood cell homeostasis regulation (1) Vps25 none np   20540764
Blood cell homeostasis regulation (2) Vps25 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) Vps25 none 1.8   20540764
Blood cell homeostasis regulation (4) Vps25 none 0   20540764
Blood cell homeostasis regulation (5) Vps25 none 0   20540764
Wnt proteins secretion Vps25 none -0.2   22094269
Hippo pathway regulation Vps25 none 0.46   23263283
Glycosylation regulation (1) Vps25 none sp   21203496

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