Genomics
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21 Alleles
88 Clones
23 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0032940:11 | Mio:11 |
| FBgn0032940:10 | Mio:10 |
| FBgn0032940:9 | Mio:9 |
| FBgn0032940:8 | Mio:8 |
| FBgn0032940:7 | Mio:7 |
| FBgn0032940:6 | Mio:6 |
| FBgn0032940:5 | Mio:5 |
| FBgn0032940:4 | Mio:4 |
| FBgn0032940:3 | Mio:3 |
| FBgn0032940:1 | Mio:1 |
| FBgn0032940:19 | Mio:19 |
| FBgn0032940:2 | Mio:2 |
| FBgn0032940:18 | Mio:18 |
| FBgn0032940:20 | Mio:20 |
| FBgn0032940:16 | Mio:16 |
| FBgn0032940:12 | Mio:12 |
| FBgn0032940:21 | Mio:21 |
| FBgn0032940:14 | Mio:14 |
| FBgn0032940:23 | Mio:23 |
| FBgn0032940:17 | Mio:17 |
| FBgn0032940:22 | Mio:22 |
| FBgn0032940:15 | Mio:15 |
| FBgn0032940:13 | Mio:13 |
11 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0081527 | Mio |
| FBtr0301463 | Mio |
| FBtr0301464 | Mio |
| FBtr0301462 | Mio |
| FBtr0301457 | Mio |
| FBtr0081524 | Mio |
| FBtr0301460 | Mio |
| FBtr0301461 | Mio |
| FBtr0081525 | Mio |
| FBtr0301458 | Mio |
| FBtr0301459 | Mio |
22 UTRs
Other
77 Pathways
- PKA activation,
- NGF signalling via TRKA from the plasma membrane,
- CaM pathway,
- IRS activation,
- DINR-mediated activation,
- EGFR interacts with phospholipase C-gamma,
- SLC-mediated transmembrane transport,
- Signaling by EGFR,
- Insulin receptor mediated signaling,
- Regulation of Rheb GTPase activity by AMPK,
- Signaling by ERBB2,
- GPCR downstream signaling,
- Glucose transport,
- PKA-mediated phosphorylation of key metabolic factors,
- Integration of energy metabolism,
- DAP12 interactions,
- Glucose metabolism,
- Calmodulin induced events,
- Regulation of Water Balance by Renal Aquaporins,
- Phospholipase C-mediated cascade,
- Glycolysis,
- Innate Immune System,
- mTOR signalling,
- Regulation of gene expression in beta cells,
- Insulin receptor signalling cascade,
- Insulin signaling pathway,
- DARPP-32 events,
- IGF1R signaling cascade,
- Signaling by FGFR in disease,
- DAP12 signaling,
- Fructose catabolism,
- Regulation of beta-cell development,
- ChREBP activates metabolic gene expression,
- Downstream signaling of activated FGFR,
- Insulin receptor recycling,
- mTORC1-mediated signalling,
- Transmembrane transport of small molecules,
- Signaling by FGFR,
- PKA-mediated phosphorylation of CREB,
- PI3K Cascade,
- IRS-related events,
- PLC-gamma1 signalling,
- Ca-dependent events,
- Release of eIF4E,
- IRS-related events triggered by IGF1R,
- TOR signaling pathway,
- Immune System,
- Pentose phosphate pathway (hexose monophosphate shunt),
- Signaling by NGF,
- Opioid Signalling,
- PLCG1 events in ERBB2 signaling,
- Disease,
- Aquaporin-mediated transport,
- Signaling by GPCR,
- PP2A-mediated dephosphorylation of key metabolic factors,
- Signaling Pathways,
- Carbohydrate metabolism,
- Inositol phosphate metabolism,
- Hexose uptake,
- Developmental Biology,
- Glucagon signaling in metabolic regulation,
- Metabolism,
- Downstream signal transduction,
- Regulation of AMPK activity via LKB1,
- Signaling by PDGF,
- G alpha (s) signalling events,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- PLC beta mediated events,
- G-protein mediated events,
- AMPK inhibits chREBP transcriptional activation activity,
- Insulin effects increased synthesis of Xylulose-5-Phosphate,
- DAG and IP3 signaling,
- PKA activation in glucagon signalling,
- IRS-mediated signalling,
- PKB-mediated events,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Signaling by EGFR in Cancer
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35402 | NCBI Entrez Gene identifiers | FBgn0032940 |
| 61352 | BioGRID | FBgn0032940 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
25 Introns
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Mio | none | -0.072163159 | 19067489 | |
| Lipid storage | Mio | none | -3.834643288 | 19067489 | |
| Lipid storage | Mio | none | 0.763274805 | 19067489 | |
| Lipid storage | Mio | none | -1.61187866 | 19067489 | |
| Lipid storage | Mio | none | -0.024460416 | 19067489 | |
| Lipid storage | Mio | none | -0.598731609 | 19067489 | |
| ERK signaling | Mio | ERK activation reduced | weak | 17086199 | |
| Cell size and cell-cycle regulation (1) | Mio | Increased G2 DNA content | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | Mio | none | 1.334 | 16496002 | |
| Cell size and cell-cycle regulation (3) | Mio | none | 472 | 16496002 | |
| Cell size and cell-cycle regulation (4) | Mio | Increased number of mitotic cells | 0.7 | 16496002 | |
| Dendrite pattern formation | Mio | none | np | 16547170 | |
| Heat nociception (1) | Mio | none | -1.17 | 21074052 | |
| Heart development and function (1) | Mio | none | 1 | 20371351 | |
| Heart development and function (1) | Mio | none | 1 | 20371351 | |
| RTK-Ras-ERK pathway regulation (1) | Mio | Decreased ERK phosphorylation after EGF stimulation | -1.74 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | Mio | none | -1.3 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Mio | none | -0.14 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Mio | Decreased ERK phosphorylation after sSpitz and EGF stimulation | -1.66 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | Mio | Downregulation of Hippo pathway | 5.48 | 23263283 | |
| Glycosylation regulation (1) | Mio | none | sp | 21203496 |
