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Gene : Nelf-E D. melanogaster

DB identifier  ? FBgn0017430 Secondary Identifier  ? CG5994
Name  ? Negative elongation factor E Source  FlyBase
  • synonyms:
  • NELF-E,
  • NELF,
  • CG5994,
  • negative elongation factor,
  • FBan0005994,
  • NelfE,
  • anonymous-66Da,
  • unnamed,
  • anon-66Da,
  • dNelf-E,
  • FBgn0017430

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10 Alleles

DB identifier Symbol Allele Class Organism
FBal0198061 Nelf-E[Act5C.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0141630 Nelf-E[dsRNA.IR.Scer\UAS]   Drosophila melanogaster
FBal0283813 Nelf-E[EY07065]   Drosophila melanogaster
FBal0257214 Nelf-E[HMS00525]   Drosophila melanogaster
FBal0182524 Nelf-E[c00506]   Drosophila melanogaster
FBal0246085 Nelf-E[Hsp83.PG]   Drosophila melanogaster
FBal0207733 Nelf-E[GD9903]   Drosophila melanogaster
FBal0241304 Nelf-E[MB12251]   Drosophila melanogaster
FBal0247325 Nelf-E[Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0222476 Nelf-E[c00768]   Drosophila melanogaster

49 Clones

Secondary Identifier DB identifier
UUGC0640 FBcl0006555
EC40779 FBcl0069537
EK046309 FBcl0103242
EK220523 FBcl0103256
EK179306 FBcl0103258
EK255846 FBcl0103260
EK046009 FBcl0103262
EK207449 FBcl0103264
LD15578 FBcl0159708
RE39541 FBcl0223814
RE14181 FBcl0224483
RE38139 FBcl0226071
RE68465 FBcl0226150
RE64690 FBcl0226223
RE71206 FBcl0226492
RH52007 FBcl0265399
Dmel_neb_012123_0569_3476 FBcl0381336
FGH110E02 FBcl0387325
FGM219B11 FBcl0390551
RP003323398 FBcl0669731
RP003434246 FBcl0669736
RP003215854 FBcl0669747
RP003110972 FBcl0669751
RP003557057 FBcl0669764
RP003320517 FBcl0669770
RP003464685 FBcl0669771
RP003254072 FBcl0669775
RP003190244 FBcl0669787
RP003305000 FBcl0669790
RP003054297 FBcl0669823

4 Exons

DB identifier Symbol
FBgn0017430:1 Nelf-E:1
FBgn0017430:4 Nelf-E:4
FBgn0017430:3 Nelf-E:3
FBgn0017430:2 Nelf-E:2

1 Transcripts

DB identifier Gene
FBtr0076650 Nelf-E

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076650-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076650-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38982 NCBI Entrez Gene identifiers FBgn0017430
64390 BioGRID FBgn0017430

12 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  
Fly Transcription Factor/microRNA Regulatory Network  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 328.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 322.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 165.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 186.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 347.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 378.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 314.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 306.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 398.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 361.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 447.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 167.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 342.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 398.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 385.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 302.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 346.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 297.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 472.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 421.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 422.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 535.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 465.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 378.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 360.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1645.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1258.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1228.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 998.0
FBgn0017430 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1083.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0017430:4_FBgn0017430:3 Drosophila melanogaster
intron_FBgn0017430:3_FBgn0017430:2 Drosophila melanogaster
intron_FBgn0017430:2_FBgn0017430:1 Drosophila melanogaster

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Nelf-E none 0.106649085   19067489
Lipid storage Nelf-E none -0.264235778   19067489
Histone pre-mRNA processing Nelf-E Histone pre-mRNA processing defect 2   18042462
Cell size and cell-cycle regulation (1) Nelf-E none sp   16496002
Mitochondrial biogenesis and function Nelf-E Decreased mitochondrial citrate synthase activity 0.691   18042644
Muscle morphogenesis and function (1) Nelf-E Weak flyer np   20220848
Muscle morphogenesis and function (1) Nelf-E Lethal np   20220848
Heart development and function (1) Nelf-E none 1   20371351
Heart development and function (1) Nelf-E none 1   20371351
Serratia marcescens infection (1) Nelf-E none 1   19520911
Notch pathway regulation (4) Nelf-E Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Nelf-E Bristle morphology defects, notum malformation death sp   19363474
Self-renewal and differentiation in neural stem cells Nelf-E GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Pol II elongation Nelf-E none 110 20 min heat shock 19279664
Notch pathway regulation (1) Nelf-E Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Nelf-E none -0.444   20074523
Hippo pathway regulation Nelf-E none -0.11   23263283
Huntingtin (Htt) aggregates formation Nelf-E Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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