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Gene : Galphas D. melanogaster

DB identifier  ? FBgn0001123 Secondary Identifier  ? CG2835
Name  ? G protein alpha s subunit Source  FlyBase
  • synonyms:
  • G-alpha-60A,
  • Gs-alpha60A,
  • G-salpha60A,
  • GSalpha,
  • Galpha60A,
  • dG[[alphas]],
  • G[[s]],
  • Galpha[[s]],
  • Gsalpha60A,
  • G-alpha s,
  • G[[S]]alpha,
  • GalphaS,
  • Gs,
  • stimulatory alpha subunit of G protein,
  • G protein salpha 60A,
  • FBgn0001123,
  • G[[s]]-alpha-60A,
  • CG2835,
  • Gs-alpha,
  • G[[alphas]],
  • FBan0002835,
  • G-5alpha,
  • DGsalpha,
  • DGs

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27 Alleles

DB identifier Symbol Allele Class Organism
FBal0282882 Galphas[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0126529 Galphas[R67]   Drosophila melanogaster
FBal0183473 Galphas[dsRNA.cGa]   Drosophila melanogaster
FBal0264672 Galphas[NIG.2835R]   Drosophila melanogaster
FBal0240155 Galphas[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0183472 Galphas[e04616]   Drosophila melanogaster
FBal0156447 Galphas[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0249428 Galphas[VDRC.cUa]   Drosophila melanogaster
FBal0029792 Galphas[P1]   Drosophila melanogaster
FBal0264673 Galphas[pept.Scer\UAS]   Drosophila melanogaster
FBal0126532 Galphas[R19]   Drosophila melanogaster
FBal0207067 Galphas[GD8547]   Drosophila melanogaster
FBal0235134 Galphas[KK107742]   Drosophila melanogaster
FBal0095722 Galphas[B19] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0243438 Galphas[SH0782]   Drosophila melanogaster
FBal0263659 Galphas[tH3]   Drosophila melanogaster
FBal0126533 Galphas[+t10]   Drosophila melanogaster
FBal0058938 Galphas[Scer\UAS.cCa]   Drosophila melanogaster
FBal0126531 Galphas[R33]   Drosophila melanogaster
FBal0125409 Galphas[R60] loss of function allele Drosophila melanogaster
FBal0058939 Galphas[Q215L.Scer\UAS]   Drosophila melanogaster
FBal0126528 Galphas[R79]   Drosophila melanogaster
FBal0242431 Galphas[JF03255]   Drosophila melanogaster
FBal0102987 Galphas[L215Q.ninaE]   Drosophila melanogaster
FBal0183471 Galphas[e04617]   Drosophila melanogaster
FBal0183474 Galphas[W24.Scer\UAS]   Drosophila melanogaster
FBal0126530 Galphas[R65]   Drosophila melanogaster

64 Clones

Secondary Identifier DB identifier
EK068001 FBcl0348628
EK194764 FBcl0348629
DPiM_LD26182 FBcl0741988
EK180124 FBcl0007992
EK013422 FBcl0008000
EK154311 FBcl0008024
EK186433 FBcl0008034
EK092254 FBcl0008044
EK119923 FBcl0008056
EK253728 FBcl0008068
CK01529 FBcl0059933
EC36824 FBcl0068485
EC29386 FBcl0068487
EN00623 FBcl0093637
EK142063 FBcl0094764
GH13496 FBcl0126559
GH20707 FBcl0129461
HL01984 FBcl0150260
LD26182 FBcl0175894
LP07021 FBcl0189100
RE13289 FBcl0219354
RE43514 FBcl0219364
RE70828 FBcl0219376
RE72351 FBcl0219387
RE43860 FBcl0219413
RE12953 FBcl0225534
RE73367 FBcl0226321
RE12729 FBcl0227310
RE69318 FBcl0229034
RE65114 FBcl0229067

12 Exons

DB identifier Symbol
FBgn0001123:1 Galphas:1
FBgn0001123:4 Galphas:4
FBgn0001123:5 Galphas:5
FBgn0001123:6 Galphas:6
FBgn0001123:7 Galphas:7
FBgn0001123:8 Galphas:8
FBgn0001123:9 Galphas:9
FBgn0001123:11 Galphas:11
FBgn0001123:12 Galphas:12
FBgn0001123:2 Galphas:2
FBgn0001123:10 Galphas:10
FBgn0001123:3 Galphas:3

5 Transcripts

DB identifier Gene
FBtr0072142 Galphas
FBtr0301411 Galphas
FBtr0072144 Galphas
FBtr0072143 Galphas
FBtr0343279 Galphas

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072142-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072143-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072144-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301411-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0343279-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072142-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072143-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072144-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301411-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0343279-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37805 NCBI Entrez Gene identifiers FBgn0001123
63395 BioGRID FBgn0001123

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2115.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2096.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1062.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 897.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1461.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1311.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1464.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1129.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1456.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2488.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1895.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1254.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1322.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1472.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1523.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1410.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1882.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2204.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1567.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1459.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 820.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2187.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2043.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2058.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1287.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 204.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1232.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2850.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2013.0
FBgn0001123 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1754.0

12 Introns

DB identifier
Organism . Name
intron_FBgn0001123:1_FBgn0001123:4 Drosophila melanogaster
intron_FBgn0001123:4_FBgn0001123:5 Drosophila melanogaster
intron_FBgn0001123:5_FBgn0001123:6 Drosophila melanogaster
intron_FBgn0001123:6_FBgn0001123:7 Drosophila melanogaster
intron_FBgn0001123:7_FBgn0001123:8 Drosophila melanogaster
intron_FBgn0001123:8_FBgn0001123:9 Drosophila melanogaster
intron_FBgn0001123:9_FBgn0001123:11 Drosophila melanogaster
intron_FBgn0001123:11_FBgn0001123:12 Drosophila melanogaster
intron_FBgn0001123:2_FBgn0001123:4 Drosophila melanogaster
intron_FBgn0001123:9_FBgn0001123:10 Drosophila melanogaster
intron_FBgn0001123:10_FBgn0001123:12 Drosophila melanogaster
intron_FBgn0001123:3_FBgn0001123:5 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Galphas none 1.215616068   19067489
Lipid storage Galphas none 0.651411359   19067489
Hedgehog signaling Galphas Decreased Hedgehog reporter activity -3.59   16311596
Cell size and cell-cycle regulation (1) Galphas none sp   16496002
Muscle morphogenesis and function (1) Galphas Lethal np   20220848
Muscle morphogenesis and function (1) Galphas none np   20220848
Muscle morphogenesis and function (2) Galphas Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Galphas none 0.12   21074052
Heat nociception (1) Galphas none -1.17   21074052
Heart development and function (1) Galphas none 1   20371351
Heart development and function (2) Galphas Decreased viability 3.14   20371351
Serratia marcescens infection (1) Galphas none -0.226666666666666   19520911
Notch pathway regulation (4) Galphas Notum malformation death 2   19363474
Notch pathway regulation (4) Galphas Notum malformation death 1   19363474
Hh pathway regulation Galphas Downregulation of Hh pathway -0.386742033895643   17903264
Hh pathway regulation Galphas Downregulation of Hh pathway -0.473517833472617   17903264
Blood cell homeostasis regulation (1) Galphas none np   20540764
Blood cell homeostasis regulation (2) Galphas none np   20540764
Hippo pathway regulation Galphas none -0.55   23263283
Glycosylation regulation (1) Galphas none sp   21203496

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