Genomics
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202 Alleles
48 Clones
4 Exons
DB identifier | Symbol |
---|---|
FBgn0001168:2 | h:2 |
FBgn0001168:3 | h:3 |
FBgn0001168:4 | h:4 |
FBgn0001168:1 | h:1 |
4 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0076569-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0100153-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0076569-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0100153-3-prime-utr | Drosophila melanogaster |
Other
25 Pathways
- NICD traffics to nucleus,
- Signaling by NOTCH,
- Signaling by NOTCH1 in Cancer,
- Signaling by NOTCH4,
- Pre-NOTCH Processing in the Endoplasmic Reticulum,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- Signaling by NOTCH2,
- Pre-NOTCH Processing in Golgi,
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- Activated NOTCH1 Transmits Signal to the Nucleus,
- Signaling by NOTCH3,
- Signaling Pathways,
- Signaling by NOTCH1 HD Domain Mutants in Cancer,
- Regulation of gene expression in early pancreatic precursor cells,
- Developmental Biology,
- FBXW7 Mutants and NOTCH1 in Cancer,
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant,
- Signaling by NOTCH1,
- Disease,
- A third proteolytic cleavage releases NICD,
- Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor,
- NOTCH2 Activation and Transmission of Signal to the Nucleus,
- Regulation of beta-cell development,
- Pre-NOTCH Expression and Processing
2 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
38995 | NCBI Entrez Gene identifiers | FBgn0001168 |
64402 | BioGRID | FBgn0001168 |
12 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
Swiss-Prot data set | http://ca.expasy.org/sprot |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores | |
Fly Transcription Factor/microRNA Regulatory Network |
55 Expression Scores
12 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | h | none | 2.256196809 | 19067489 | |
Lipid storage | h | none | -2.554396091 | 19067489 | |
Lipid storage | h | none | 0.555875113 | 19067489 | |
Lipid storage | h | none | 0.788243332 | 19067489 | |
ERK signaling | h | ERK activation reduced | strong | 17086199 | |
Wnt signaling | h | Increased Wnt reporter activity | 5.1 | 15817814 | |
Cell size and cell-cycle regulation (1) | h | none | sp | 16496002 | |
Dendrite pattern formation | h | none | np | 16547170 | |
Combinatorial effect with methyl methanesulphonate (2) | h | none | sp | 19543366 | |
Mutant human huntingtin aggregation | h | Decreased mutant human huntingtin aggregation | <= -2 | 19789644 | |
Hippo pathway regulation | h | none | 0.49 | 23263283 | |
Glycosylation regulation (1) | h | none | sp | 21203496 |