Genomics
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10 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0268404 | RpL5[dsRNA.WIZ.Scer\UAS] | Drosophila melanogaster | |
| FBal0155944 | RpL5[Wee-P28] | Drosophila melanogaster | |
| FBal0259975 | RpL5[KK115256] | Drosophila melanogaster | |
| FBal0181798 | RpL5[2d1] | Drosophila melanogaster | |
| FBal0181797 | RpL5[2d2] | Drosophila melanogaster | |
| FBal0141556 | RpL5[MtnA.T:Hsap\MYC] | Drosophila melanogaster | |
| FBal0286888 | RpL5[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286889 | RpL5[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0194851 | RpL5[dsRNA.cDa] | Drosophila melanogaster | |
| FBal0272621 | RpL5[NIG.17489R] | Drosophila melanogaster |
1498 Clones
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0064225:6 | RpL5:6 |
| FBgn0064225:4 | RpL5:4 |
| FBgn0064225:3 | RpL5:3 |
| FBgn0064225:2 | RpL5:2 |
| FBgn0064225:7 | RpL5:7 |
| FBgn0064225:5 | RpL5:5 |
| FBgn0064225:8 | RpL5:8 |
| FBgn0064225:1 | RpL5:1 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0111129-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0111132-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0332633-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0111129-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0111132-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0332633-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- Transport of Mature Transcript to Cytoplasm,
- Metabolism of proteins,
- Peptide chain elongation,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Processing of Capped Intronless Pre-mRNA,
- Formation of the Early Elongation Complex,
- Metabolism of RNA,
- RNA Polymerase II Transcription,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- RNA Polymerase II Transcription Elongation,
- Processing of Capped Intron-Containing Pre-mRNA,
- Elongation arrest and recovery,
- Eukaryotic Translation Termination,
- Ribosomal scanning and start codon recognition,
- 3' -UTR-mediated translational regulation,
- Nonsense-Mediated Decay,
- Post-Elongation Processing of the Transcript,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Transcription,
- Cap-dependent Translation Initiation,
- mRNA Processing,
- RNA Polymerase II Promoter Escape,
- Processing of Intronless Pre-mRNAs,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- RNA Polymerase II Transcription Termination,
- Eukaryotic Translation Elongation,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- RNA Polymerase II Transcription Initiation,
- RNA Polymerase II Pre-transcription Events,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Eukaryotic Translation Initiation,
- Post-Elongation Processing of Intronless pre-mRNA,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- SRP-dependent cotranslational protein targeting to membrane,
- mRNA Capping,
- Metabolism of mRNA,
- Cleavage of Growing Transcript in the Termination Region,
- Formation of RNA Pol II elongation complex,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- Formation of a pool of free 40S subunits,
- SLBP independent Processing of Histone Pre-mRNAs,
- Translation,
- Transport of the SLBP independent Mature mRNA,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Transport of the SLBP Dependant Mature mRNA,
- Gene Expression
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 3355124 | NCBI Entrez Gene identifiers | FBgn0064225 |
| 78249 | BioGRID | FBgn0064225 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
28 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL5 | none | -1.167864242 | 19067489 | |
| Lipid storage | RpL5 | none | 6.564346737 | 19067489 | |
| ERK signaling | RpL5 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpL5 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpL5 | Binucleate cells with decreased viability | weak | 15547975 | |
| Intracellular Listeria monocytogenes infection | RpL5 | Increased GFP protein expression | strong | 16020693 | |
| Drosophila C virus infection | RpL5 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL5 | Decreased Hedgehog reporter activity | -4.1 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL5 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL5 | none | sp | 16496002 | |
| Influenza replication | RpL5 | Decreased Influenza replication | -1.36/-3.71 | 18615016 | |
| Mutant human huntingtin aggregation | RpL5 | Decreased mutant human huntingtin aggregation | <= -2 | 19789644 | |
| Muscle morphogenesis and function (1) | RpL5 | Lethal | np | 20220848 | |
| Heat nociception (1) | RpL5 | Lethal | -1.17 | 21074052 | |
| Heart development and function (1) | RpL5 | Adult lethal | 0.5 | 20371351 | |
| Heart development and function (2) | RpL5 | Decreased viability | 5.49 | 20371351 | |
| Notch pathway regulation (4) | RpL5 | Completely lethal (before pupal) | sp | 19363474 | |
| Hh pathway regulation | RpL5 | Downregulation of Hh pathway | -0.607473207020254 | 17903264 | |
| Blood cell homeostasis regulation (1) | RpL5 | Increased melanotic mass formation | np | 20540764 | |
| Blood cell homeostasis regulation (2) | RpL5 | Increased melanotic mass formation | np | 20540764 | |
| RTK-Ras-ERK pathway regulation (1) | RpL5 | none | 0.19 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpL5 | Decreased ERK phosphorylation after EGF stimulation | -5.51 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL5 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.94 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL5 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.18 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpL5 | none | -2.52 | 23263283 | |
| Glycosylation regulation (1) | RpL5 | Increased alpha1,6-fucose Chp glycosylation, increased GlcNAcb1-4GlcNAc Chp glycosylation, increased mannose Chp glycosylation | sp | 21203496 | |
| Glycosylation regulation (2) | RpL5 | Effect on Chp glycosylation | np | 21203496 | |
| Glycosylation regulation (3) | RpL5 | Effect on Chp glycosylation | np | 21203496 |
