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Gene : RpL5 D. melanogaster

DB identifier  ? FBgn0064225 Secondary Identifier  ? CG17489
Name  ? Ribosomal protein L5 Source  FlyBase
  • synonyms:
  • E-2d,
  • yippee interacting protein 6,
  • L5,
  • FBgn0064225,
  • yip6,
  • Rpl5,
  • dRPL5,
  • FBan0017489,
  • Enhancer on chromosome 2, complementation group d,
  • M(2)40B,
  • FBgn0040008,
  • Rp L5,
  • ribosomal protein L5,
  • CG17489,
  • FBgn0040061

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10 Alleles

DB identifier Symbol Allele Class Organism
FBal0268404 RpL5[dsRNA.WIZ.Scer\UAS]   Drosophila melanogaster
FBal0155944 RpL5[Wee-P28]   Drosophila melanogaster
FBal0259975 RpL5[KK115256]   Drosophila melanogaster
FBal0181798 RpL5[2d1]   Drosophila melanogaster
FBal0181797 RpL5[2d2]   Drosophila melanogaster
FBal0141556 RpL5[MtnA.T:Hsap\MYC]   Drosophila melanogaster
FBal0286888 RpL5[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286889 RpL5[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0194851 RpL5[dsRNA.cDa]   Drosophila melanogaster
FBal0272621 RpL5[NIG.17489R]   Drosophila melanogaster

1498 Clones

Secondary Identifier DB identifier
GH15550 FBcl0113837
GH27446 FBcl0126723
LP07855 FBcl0185729
LP03994 FBcl0185735
RE33114 FBcl0294558
RE57391 FBcl0294566
FGH129D06 FBcl0388695
EC052848 FBcl0301534
SD13191 FBcl0304099
EN01964 FBcl0328446
RH59435 FBcl0328447
EN07245 FBcl0328448
EN02620 FBcl0328449
LD08542 FBcl0328450
LD16719 FBcl0328451
GM04586 FBcl0328452
LD42055 FBcl0328453
SD10360 FBcl0336766
RE01404 FBcl0336763
RE01353 FBcl0336764
bs38h04 FBcl0336765
LP16251 FBcl0336786
SD08808 FBcl0336767
SD05741 FBcl0336768
LD40616 FBcl0336769
LD35108 FBcl0336770
GH19253 FBcl0336771
LP08133 FBcl0336772
LP03194 FBcl0336773
GH07805 FBcl0336774

8 Exons

DB identifier Symbol
FBgn0064225:6 RpL5:6
FBgn0064225:4 RpL5:4
FBgn0064225:3 RpL5:3
FBgn0064225:2 RpL5:2
FBgn0064225:7 RpL5:7
FBgn0064225:5 RpL5:5
FBgn0064225:8 RpL5:8
FBgn0064225:1 RpL5:1

3 Transcripts

DB identifier Gene
FBtr0111129 RpL5
FBtr0332633 RpL5
FBtr0111132 RpL5

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0111129-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0111132-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332633-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0111129-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0111132-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332633-3-prime-utr Drosophila melanogaster

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49 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
3355124 NCBI Entrez Gene identifiers FBgn0064225
78249 BioGRID FBgn0064225

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 9970.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 10188.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 25070.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 30229.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 13446.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 32523.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 18108.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 31445.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 53808.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 20128.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 21061.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 31980.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 17480.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 21974.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 34772.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 25689.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 22032.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 19705.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 29410.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 15849.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 23526.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 13168.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 10892.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 10480.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 9739.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 11442.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 19331.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 17332.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 15020.0
FBgn0064225 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 10901.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0064225:6_FBgn0064225:4 Drosophila melanogaster
intron_FBgn0064225:4_FBgn0064225:3 Drosophila melanogaster
intron_FBgn0064225:3_FBgn0064225:2 Drosophila melanogaster
intron_FBgn0064225:8_FBgn0064225:5 Drosophila melanogaster
intron_FBgn0064225:5_FBgn0064225:4 Drosophila melanogaster
intron_FBgn0064225:3_FBgn0064225:1 Drosophila melanogaster
intron_FBgn0064225:7_FBgn0064225:5 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RpL5 none -1.167864242   19067489
Lipid storage RpL5 none 6.564346737   19067489
ERK signaling RpL5 ERK activation reduced weak   17086199
Drosophila C virus infection RpL5 Drosophila C virus replication down np   17040126
Cytokinesis regulation RpL5 Binucleate cells with decreased viability weak   15547975
Intracellular Listeria monocytogenes infection RpL5 Increased GFP protein expression strong   16020693
Drosophila C virus infection RpL5 Drosophila C virus infection reduced np   15713840
Hedgehog signaling RpL5 Decreased Hedgehog reporter activity -4.1   16311596
Constitutive protein secretion and Golgi organization (1) RpL5 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) RpL5 none sp   16496002
Influenza replication RpL5 Decreased Influenza replication -1.36/-3.71   18615016
Mutant human huntingtin aggregation RpL5 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) RpL5 Lethal np   20220848
Heat nociception (1) RpL5 Lethal -1.17   21074052
Heart development and function (1) RpL5 Adult lethal 0.5   20371351
Heart development and function (2) RpL5 Decreased viability 5.49   20371351
Notch pathway regulation (4) RpL5 Completely lethal (before pupal) sp   19363474
Hh pathway regulation RpL5 Downregulation of Hh pathway -0.607473207020254   17903264
Blood cell homeostasis regulation (1) RpL5 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) RpL5 Increased melanotic mass formation np   20540764
RTK-Ras-ERK pathway regulation (1) RpL5 none 0.19 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) RpL5 Decreased ERK phosphorylation after EGF stimulation -5.51 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpL5 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.94 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpL5 Increased ERK phosphorylation after sSpitz and EGF stimulation 3.18 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation RpL5 none -2.52   23263283
Glycosylation regulation (1) RpL5 Increased alpha1,6-fucose Chp glycosylation, increased GlcNAcb1-4GlcNAc Chp glycosylation, increased mannose Chp glycosylation sp   21203496
Glycosylation regulation (2) RpL5 Effect on Chp glycosylation np   21203496
Glycosylation regulation (3) RpL5 Effect on Chp glycosylation np   21203496

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