Genomics
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11 Alleles
DB identifier | Symbol | Allele Class | Organism |
---|---|---|---|
FBal0284515 | RpL36[Scer\UAS.T:Disc\RFP] | Drosophila melanogaster | |
FBal0103722 | RpL36[G0471] | Drosophila melanogaster | |
FBal0130782 | RpL36[PG29] | Drosophila melanogaster | |
FBal0033782 | RpL36[+t10] | Drosophila melanogaster | |
FBal0048856 | RpL36[y74k24.1] | Drosophila melanogaster | |
FBal0011883 | RpL36[B46] | hypomorphic allele - genetic evidence | Drosophila melanogaster |
FBal0193398 | RpL36[+t4] | Drosophila melanogaster | |
FBal0287405 | RpL36[Scer\UAS.ORF] | Drosophila melanogaster | |
FBal0287406 | RpL36[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
FBal0208352 | RpL36[GD8657] | Drosophila melanogaster | |
FBal0235012 | RpL36[KK107555] | Drosophila melanogaster |
553 Clones
6 Exons
DB identifier | Symbol |
---|---|
FBgn0002579:6 | RpL36:6 |
FBgn0002579:2 | RpL36:2 |
FBgn0002579:1 | RpL36:1 |
FBgn0002579:4 | RpL36:4 |
FBgn0002579:5 | RpL36:5 |
FBgn0002579:3 | RpL36:3 |
4 Transcripts
DB identifier | Gene |
---|---|
FBtr0070155 | RpL36 |
FBtr0070158 | RpL36 |
FBtr0070157 | RpL36 |
FBtr0070156 | RpL36 |
8 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0070155-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0070156-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0070157-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0070158-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0070155-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0070156-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0070157-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0070158-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- Metabolism of mRNA,
- Transcription,
- Metabolism of proteins,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Peptide chain elongation,
- Post-Elongation Processing of the Transcript,
- Post-Elongation Processing of Intronless pre-mRNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Formation of a pool of free 40S subunits,
- Ribosomal scanning and start codon recognition,
- RNA Polymerase II Transcription Initiation,
- Formation of RNA Pol II elongation complex,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- mRNA Capping,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- RNA Polymerase II Transcription,
- Eukaryotic Translation Termination,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Cleavage of Growing Transcript in the Termination Region,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of the SLBP independent Mature mRNA,
- Formation of the Early Elongation Complex,
- Processing of Capped Intron-Containing Pre-mRNA,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- 3' -UTR-mediated translational regulation,
- RNA Polymerase II Transcription Termination,
- Eukaryotic Translation Initiation,
- Metabolism of RNA,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- RNA Polymerase II Pre-transcription Events,
- Transport of the SLBP Dependant Mature mRNA,
- Gene Expression,
- Processing of Capped Intronless Pre-mRNA,
- mRNA Processing,
- RNA Pol II CTD phosphorylation and interaction with CE,
- SRP-dependent cotranslational protein targeting to membrane,
- Eukaryotic Translation Elongation,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Nonsense-Mediated Decay,
- Translation,
- Elongation arrest and recovery,
- Processing of Intronless Pre-mRNAs,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Cap-dependent Translation Initiation,
- Transport of Mature Transcript to Cytoplasm,
- RNA Polymerase II Promoter Escape,
- RNA Polymerase II Transcription Elongation
3 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
31009 | NCBI Entrez Gene identifiers | FBgn0002579 |
34098 | NCBI Entrez Gene identifiers | FBgn0002579 |
57577 | BioGRID | FBgn0002579 |
11 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
Swiss-Prot data set | http://ca.expasy.org/sprot |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
5 Introns
23 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | RpL36 | none | 1.730928413 | 19067489 | |
Lipid storage | RpL36 | none | 2.448803634 | 19067489 | |
Cytokinesis regulation | RpL36 | Binucleate cells with decreased viability | weak | 15547975 | |
Hedgehog signaling | RpL36 | Decreased Hedgehog reporter activity | -2.99 | 16311596 | |
Constitutive protein secretion and Golgi organization (1) | RpL36 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
Cell size and cell-cycle regulation (1) | RpL36 | Increased G1 DNA content, decreased G2 DNA content, decreased viability | sp | 16496002 | |
Cell size and cell-cycle regulation (2) | RpL36 | Decreased viability | 0.762 | 16496002 | |
Cell size and cell-cycle regulation (3) | RpL36 | none | 420 | 16496002 | |
Candida albicans phagocytosis (1) | RpL36 | none | np | 16336044 | |
Lipid storage | RpL36 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
Heat nociception (1) | RpL36 | none | -1.17 | 21074052 | |
Heart development and function (1) | RpL36 | Embryonic lethal or no offspring | 0 | 20371351 | |
Serratia marcescens infection (1) | RpL36 | none | -1.1 | 19520911 | |
Notch pathway regulation (4) | RpL36 | Completely lethal (pupal) | sp | 19363474 | |
Hh pathway regulation | RpL36 | Downregulation of Hh pathway | -0.419286479255493 | 17903264 | |
Hh pathway regulation | RpL36 | Downregulation of Hh pathway | -0.587217917459334 | 17903264 | |
Notch pathway regulation (1) | RpL36 | Downregulation of Notch pathway | np | 20493818 | |
Adiposity regulation (1) | RpL36 | none | -0.025 | 20074523 | |
RTK-Ras-ERK pathway regulation (1) | RpL36 | Increased ERK phosphorylation after EGF stimulation | 4.06 | 0 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (1) | RpL36 | Decreased ERK phosphorylation after EGF stimulation | -3.22 | 10 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | RpL36 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.69 | 10 minutes sSpitz stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | RpL36 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.05 | 30 minutes sSpitz stimulation | 22028469 |
Hippo pathway regulation | RpL36 | none | -2.54 | 23263283 |