Genomics
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11 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0284515 | RpL36[Scer\UAS.T:Disc\RFP] | Drosophila melanogaster | |
| FBal0103722 | RpL36[G0471] | Drosophila melanogaster | |
| FBal0130782 | RpL36[PG29] | Drosophila melanogaster | |
| FBal0033782 | RpL36[+t10] | Drosophila melanogaster | |
| FBal0048856 | RpL36[y74k24.1] | Drosophila melanogaster | |
| FBal0011883 | RpL36[B46] | hypomorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0193398 | RpL36[+t4] | Drosophila melanogaster | |
| FBal0287405 | RpL36[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287406 | RpL36[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208352 | RpL36[GD8657] | Drosophila melanogaster | |
| FBal0235012 | RpL36[KK107555] | Drosophila melanogaster |
553 Clones
6 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0002579:6 | RpL36:6 |
| FBgn0002579:2 | RpL36:2 |
| FBgn0002579:1 | RpL36:1 |
| FBgn0002579:4 | RpL36:4 |
| FBgn0002579:5 | RpL36:5 |
| FBgn0002579:3 | RpL36:3 |
4 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0070155 | RpL36 |
| FBtr0070158 | RpL36 |
| FBtr0070157 | RpL36 |
| FBtr0070156 | RpL36 |
8 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0070155-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0070156-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0070157-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0070158-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070155-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070156-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070157-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070158-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- Elongation arrest and recovery,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Transport of the SLBP Dependant Mature mRNA,
- Post-Elongation Processing of Intronless pre-mRNA,
- Eukaryotic Translation Elongation,
- RNA Polymerase II Transcription,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- mRNA Processing,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Transport of the SLBP independent Mature mRNA,
- Metabolism of proteins,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Gene Expression,
- SLBP independent Processing of Histone Pre-mRNAs,
- RNA Polymerase II Transcription Elongation,
- Transcription,
- Nonsense-Mediated Decay,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- SRP-dependent cotranslational protein targeting to membrane,
- Translation,
- Peptide chain elongation,
- Cap-dependent Translation Initiation,
- Metabolism of RNA,
- RNA Polymerase II Promoter Escape,
- Formation of a pool of free 40S subunits,
- 3' -UTR-mediated translational regulation,
- Formation of the Early Elongation Complex,
- Metabolism of mRNA,
- Eukaryotic Translation Initiation,
- Processing of Capped Intron-Containing Pre-mRNA,
- RNA Pol II CTD phosphorylation and interaction with CE,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Eukaryotic Translation Termination,
- Processing of Capped Intronless Pre-mRNA,
- RNA Polymerase II Transcription Termination,
- RNA Polymerase II Pre-transcription Events,
- Processing of Intronless Pre-mRNAs,
- RNA Polymerase II Transcription Initiation,
- Cleavage of Growing Transcript in the Termination Region,
- Formation of RNA Pol II elongation complex,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Ribosomal scanning and start codon recognition,
- Transport of Mature Transcript to Cytoplasm,
- mRNA Capping,
- Post-Elongation Processing of the Transcript,
- Transport of Mature mRNAs Derived from Intronless Transcripts
3 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31009 | NCBI Entrez Gene identifiers | FBgn0002579 |
| 34098 | NCBI Entrez Gene identifiers | FBgn0002579 |
| 57577 | BioGRID | FBgn0002579 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
5 Introns
23 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL36 | none | 1.730928413 | 19067489 | |
| Lipid storage | RpL36 | none | 2.448803634 | 19067489 | |
| Cytokinesis regulation | RpL36 | Binucleate cells with decreased viability | weak | 15547975 | |
| Hedgehog signaling | RpL36 | Decreased Hedgehog reporter activity | -2.99 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL36 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL36 | Increased G1 DNA content, decreased G2 DNA content, decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL36 | Decreased viability | 0.762 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL36 | none | 420 | 16496002 | |
| Candida albicans phagocytosis (1) | RpL36 | none | np | 16336044 | |
| Lipid storage | RpL36 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Heat nociception (1) | RpL36 | none | -1.17 | 21074052 | |
| Heart development and function (1) | RpL36 | Embryonic lethal or no offspring | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpL36 | none | -1.1 | 19520911 | |
| Notch pathway regulation (4) | RpL36 | Completely lethal (pupal) | sp | 19363474 | |
| Hh pathway regulation | RpL36 | Downregulation of Hh pathway | -0.419286479255493 | 17903264 | |
| Hh pathway regulation | RpL36 | Downregulation of Hh pathway | -0.587217917459334 | 17903264 | |
| Notch pathway regulation (1) | RpL36 | Downregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | RpL36 | none | -0.025 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpL36 | Increased ERK phosphorylation after EGF stimulation | 4.06 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpL36 | Decreased ERK phosphorylation after EGF stimulation | -3.22 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL36 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.69 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL36 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.05 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpL36 | none | -2.54 | 23263283 |
