Genomics
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5 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0286487 | RpL7[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0258932 | RpL7[KK101324] | Drosophila melanogaster | |
| FBal0257738 | RpL7[HMS01074] | Drosophila melanogaster | |
| FBal0208360 | RpL7[GD11462] | Drosophila melanogaster | |
| FBal0274424 | RpL7[NIG.4897R] | Drosophila melanogaster |
559 Clones
5 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0005593:3 | RpL7:3 |
| FBgn0005593:2 | RpL7:2 |
| FBgn0005593:4 | RpL7:4 |
| FBgn0005593:1 | RpL7:1 |
| FBgn0005593:5 | RpL7:5 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0079946-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0343653-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0079946-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0343653-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Nonsense-Mediated Decay,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of Mature Transcript to Cytoplasm,
- Processing of Capped Intron-Containing Pre-mRNA,
- Ribosomal scanning and start codon recognition,
- Eukaryotic Translation Initiation,
- Gene Expression,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Initiation,
- RNA Pol II CTD phosphorylation and interaction with CE,
- RNA Polymerase II Transcription Termination,
- Cleavage of Growing Transcript in the Termination Region,
- Processing of Intronless Pre-mRNAs,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Metabolism of RNA,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Transcription,
- 3' -UTR-mediated translational regulation,
- Translation,
- mRNA Capping,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Peptide chain elongation,
- Metabolism of proteins,
- Transport of the SLBP independent Mature mRNA,
- RNA Polymerase II Transcription,
- Elongation arrest and recovery,
- Formation of a pool of free 40S subunits,
- SRP-dependent cotranslational protein targeting to membrane,
- RNA Polymerase II Promoter Escape,
- Formation of the Early Elongation Complex,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Transport of the SLBP Dependant Mature mRNA,
- Eukaryotic Translation Termination,
- Processing of Capped Intronless Pre-mRNA,
- Formation of RNA Pol II elongation complex,
- mRNA Processing,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- RNA Polymerase II Pre-transcription Events,
- Eukaryotic Translation Elongation,
- RNA Polymerase II Transcription Elongation,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Post-Elongation Processing of the Transcript,
- Metabolism of mRNA,
- Cap-dependent Translation Initiation,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Transport of Mature mRNA derived from an Intron-Containing Transcript
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 34352 | NCBI Entrez Gene identifiers | FBgn0005593 |
| 60443 | BioGRID | FBgn0005593 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
30 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL7 | Increased lipid droplet area | 4.410802371 | 19067489 | |
| Lipid storage | RpL7 | Increased lipid droplet area | 3.529755937 | 19067489 | |
| ERK signaling | RpL7 | ERK activation reduced | strong | 17086199 | |
| Drosophila C virus infection | RpL7 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpL7 | Binucleate cells with decreased viability | medium | 15547975 | |
| Intracellular Listeria monocytogenes infection | RpL7 | Increased GFP protein expression | moderate | 16020693 | |
| Drosophila C virus infection | RpL7 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL7 | Decreased Hedgehog reporter activity | -3.86 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL7 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL7 | Increased G1 DNA content, decreased G2 DNA content, decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL7 | none | 1.038 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL7 | Decreased cell number | 368 | 16496002 | |
| Cell size and cell-cycle regulation (4) | RpL7 | none | below threshold | 16496002 | |
| Candida albicans phagocytosis (1) | RpL7 | none | np | 16336044 | |
| Lipid storage | RpL7 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpL7 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpL7 | none | np | 20220848 | |
| Heat nociception (1) | RpL7 | none | -1.17 | 21074052 | |
| Heart development and function (1) | RpL7 | Larval lethal | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpL7 | none | -0.336363636363636 | 19520911 | |
| Notch pathway regulation (4) | RpL7 | Completely lethal (before pupal) | sp | 19363474 | |
| Hh pathway regulation | RpL7 | Downregulation of Hh pathway | -0.666532624189709 | 17903264 | |
| Notch pathway regulation (1) | RpL7 | Downregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | RpL7 | none | -0.56 | 20074523 | |
| S2 cell spreading | RpL7 | none | np | 21041442 | |
| RTK-Ras-ERK pathway regulation (1) | RpL7 | none | -0.05 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpL7 | Decreased ERK phosphorylation after EGF stimulation | -4.08 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL7 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.04 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpL7 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 4.32 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpL7 | none | -0.8 | 23263283 |
