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Gene : RpL7 D. melanogaster

DB identifier  ? FBgn0005593 Secondary Identifier  ? CG4897
Name  ? Ribosomal protein L7 Source  FlyBase
  • synonyms:
  • FBgn0043838,
  • CG4897,
  • FBan0004897,
  • Rp L7,
  • L7,
  • ribosomal protein L7,
  • RPL7,
  • BEST:GH04411,
  • FBgn0005593,
  • unnamed

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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0286487 RpL7[Scer\UAS.ORF]   Drosophila melanogaster
FBal0258932 RpL7[KK101324]   Drosophila melanogaster
FBal0257738 RpL7[HMS01074]   Drosophila melanogaster
FBal0208360 RpL7[GD11462]   Drosophila melanogaster
FBal0274424 RpL7[NIG.4897R]   Drosophila melanogaster

559 Clones

Secondary Identifier DB identifier
Dmel_dig_010505_0698_2371 FBcl0373650
Dmel_dig_003810_0674_3175 FBcl0373651
Dmel_dig_008082_0634_2451 FBcl0373653
Dmel_neb_014791_0573_1352 FBcl0373652
Dmel_dig_019063_0670_1057 FBcl0373654
Dmel_neb_010788_0442_1326 FBcl0373655
Dmel_neb_011632_0080_1717 FBcl0373656
Dmel_neb_013226_0118_0365 FBcl0373657
Dmel_neb_006142_0133_0677 FBcl0373658
Dmel_neb_012195_0577_1327 FBcl0373659
Dmel_neb_013805_0094_3000 FBcl0373660
Dmel_dig_012061_0683_0473 FBcl0373661
Dmel_neb_001587_0083_3629 FBcl0373662
Dmel_neb_012349_0354_3254 FBcl0373668
Dmel_dig_010058_0595_2801 FBcl0373665
Dmel_dig_007968_0671_1213 FBcl0373663
Dmel_dig_006396_0645_1193 FBcl0373664
Dmel_neb_014151_0320_2874 FBcl0373667
Dmel_dig_011647_0619_1190 FBcl0373666
Dmel_neb_014144_0357_0770 FBcl0373669
Dmel_dig_017780_0675_1024 FBcl0373670
Dmel_neb_015688_0944_0948 FBcl0373671
Dmel_neb_013875_0331_2672 FBcl0373672
Dmel_neb_013789_0927_1306 FBcl0373673
Dmel_neb_013727_0405_2514 FBcl0373674
Dmel_dig_017819_0649_2726 FBcl0373675
Dmel_dig_008911_0599_1348 FBcl0373676
ESG0118a.B21_H09 FBcl0003043
ESG018a.E21_G01 FBcl0004853
AT12336 FBcl0021673

5 Exons

DB identifier Symbol
FBgn0005593:3 RpL7:3
FBgn0005593:2 RpL7:2
FBgn0005593:4 RpL7:4
FBgn0005593:1 RpL7:1
FBgn0005593:5 RpL7:5

2 Transcripts

DB identifier Gene
FBtr0079946 RpL7
FBtr0343653 RpL7

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079946-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0343653-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079946-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0343653-3-prime-utr Drosophila melanogaster

Interactions

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49 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34352 NCBI Entrez Gene identifiers FBgn0005593
60443 BioGRID FBgn0005593

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 10110.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 8221.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 13329.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 13434.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 13190.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 19126.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 10216.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 14741.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 18099.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 11426.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 11412.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 18212.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 11211.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 13341.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 15761.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 15067.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 11638.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 11860.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 18260.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 8588.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 15323.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 8816.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 7240.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 6829.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 6171.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 10149.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 11768.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 10746.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 8305.0
FBgn0005593 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 9579.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0005593:2_FBgn0005593:3 Drosophila melanogaster
intron_FBgn0005593:3_FBgn0005593:4 Drosophila melanogaster
intron_FBgn0005593:1_FBgn0005593:3 Drosophila melanogaster
intron_FBgn0005593:3_FBgn0005593:5 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RpL7 Increased lipid droplet area 4.410802371   19067489
Lipid storage RpL7 Increased lipid droplet area 3.529755937   19067489
ERK signaling RpL7 ERK activation reduced strong   17086199
Drosophila C virus infection RpL7 Drosophila C virus replication down np   17040126
Cytokinesis regulation RpL7 Binucleate cells with decreased viability medium   15547975
Intracellular Listeria monocytogenes infection RpL7 Increased GFP protein expression moderate   16020693
Drosophila C virus infection RpL7 Drosophila C virus infection reduced np   15713840
Hedgehog signaling RpL7 Decreased Hedgehog reporter activity -3.86   16311596
Constitutive protein secretion and Golgi organization (1) RpL7 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) RpL7 Increased G1 DNA content, decreased G2 DNA content, decreased viability sp   16496002
Cell size and cell-cycle regulation (2) RpL7 none 1.038   16496002
Cell size and cell-cycle regulation (3) RpL7 Decreased cell number 368   16496002
Cell size and cell-cycle regulation (4) RpL7 none below threshold   16496002
Candida albicans phagocytosis (1) RpL7 none np   16336044
Lipid storage RpL7 More dispersed droplets strong (but ribosomal)   18408709
Muscle morphogenesis and function (1) RpL7 Lethal np   20220848
Muscle morphogenesis and function (3) RpL7 none np   20220848
Heat nociception (1) RpL7 none -1.17   21074052
Heart development and function (1) RpL7 Larval lethal 0   20371351
Serratia marcescens infection (1) RpL7 none -0.336363636363636   19520911
Notch pathway regulation (4) RpL7 Completely lethal (before pupal) sp   19363474
Hh pathway regulation RpL7 Downregulation of Hh pathway -0.666532624189709   17903264
Notch pathway regulation (1) RpL7 Downregulation of Notch pathway np   20493818
Adiposity regulation (1) RpL7 none -0.56   20074523
S2 cell spreading RpL7 none np   21041442
RTK-Ras-ERK pathway regulation (1) RpL7 none -0.05 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) RpL7 Decreased ERK phosphorylation after EGF stimulation -4.08 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpL7 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.04 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpL7 Increased ERK phosphorylation after sSpitz and EGF stimulation 4.32 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation RpL7 none -0.8   23263283

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