Genomics
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23 Alleles
99 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0005648:1 | Pabp2:1 |
| FBgn0005648:2 | Pabp2:2 |
| FBgn0005648:3 | Pabp2:3 |
| FBgn0005648:4 | Pabp2:4 |
| FBgn0005648:5 | Pabp2:5 |
| FBgn0005648:7 | Pabp2:7 |
| FBgn0005648:6 | Pabp2:6 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088785-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088786-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088785-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088786-3-prime-utr | Drosophila melanogaster |
Other
26 Pathways
- Elongation arrest and recovery,
- RNA Polymerase II Transcription Termination,
- mRNA Capping,
- pre-mRNA splicing,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Post-Elongation Processing of Intronless pre-mRNA,
- Formation of the Early Elongation Complex,
- RNA Pol II CTD phosphorylation and interaction with CE,
- mRNA 3'-end processing,
- mRNA Splicing,
- Formation of RNA Pol II elongation complex,
- RNA Polymerase II Transcription Initiation,
- Processing of Capped Intronless Pre-mRNA,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Gene Expression,
- RNA Polymerase II Transcription,
- RNA Polymerase II Transcription Elongation,
- RNA Polymerase II Promoter Escape,
- mRNA Processing,
- Processing of Intronless Pre-mRNAs,
- Cleavage of Growing Transcript in the Termination Region,
- Post-Elongation Processing of the Transcript,
- Post-Elongation Processing of Intron-Containing pre-mRNA,
- Processing of Capped Intron-Containing Pre-mRNA,
- Transcription,
- RNA Polymerase II Pre-transcription Events
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35788 | NCBI Entrez Gene identifiers | FBgn0005648 |
| 61644 | BioGRID | FBgn0005648 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
6 Introns
33 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Pabp2 | Increased lipid droplet area | 7.994885844 | 19067489 | |
| Lipid storage | Pabp2 | Increased lipid droplet area | 4.017752499 | 19067489 | |
| ERK signaling | Pabp2 | ERK activation reduced | weak | 17086199 | |
| Cytokinesis regulation | Pabp2 | Binucleate cells with decreased viability | medium | 15547975 | |
| Constitutive protein secretion and Golgi organization (1) | Pabp2 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | Pabp2 | Decreased G1 DNA content, increased cytokinesis | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Pabp2 | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | Pabp2 | none | 1.2 | 16496002 | |
| Cell size and cell-cycle regulation (3) | Pabp2 | none | 469 | 16496002 | |
| Candida albicans phagocytosis (1) | Pabp2 | none | np | 16336044 | |
| Combinatorial effect with methyl methanesulphonate (2) | Pabp2 | none | sp | 19543366 | |
| Mutant human huntingtin aggregation | Pabp2 | Decreased mutant human huntingtin aggregation | <= -2 | 19789644 | |
| Muscle morphogenesis and function (1) | Pabp2 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | Pabp2 | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | Pabp2 | Fading Z-line | np | 20220848 | |
| Heat nociception (1) | Pabp2 | none | -1.17 | 21074052 | |
| Heart development and function (1) | Pabp2 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Pabp2 | none | 0.48076923076923 | 19520911 | |
| Notch pathway regulation (4) | Pabp2 | none | 0 | 19363474 | |
| Self-renewal and differentiation in neural stem cells | Pabp2 | GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal | sp | 21549331 | |
| Pol II elongation | Pabp2 | none | 87 | 20 min heat shock | 19279664 |
| Notch pathway regulation (1) | Pabp2 | Downregulation of Notch pathway | np | 20493818 | |
| Notch pathway regulation (2) | Pabp2 | Downregulation of Notch pathway; adult wing margin: notches | sp | C96-GAL4 | 20493818 |
| Notch pathway regulation (2) | Pabp2 | Lethal | very strong | en-GAL4 | 20493818 |
| Adiposity regulation (1) | Pabp2 | none | 0.254 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | Pabp2 | none | -0.1 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | Pabp2 | Decreased ERK phosphorylation after EGF stimulation | -1.74 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Pabp2 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.68 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Pabp2 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.51 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | Pabp2 | none | -2.57 | 23263283 |
