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Gene : if D. melanogaster

DB identifier  ? FBgn0001250 Secondary Identifier  ? CG9623
Name  ? inflated Source  FlyBase
  • synonyms:
  • FBan0009623,
  • alpha[[PS2(ms8)]],
  • alpha-PS2-integrin,
  • If,
  • alphaPS2,
  • ItgalphaPS2,
  • PSalpha2,
  • in,
  • inf,
  • alpha[[PS2]],
  • CG9623,
  • FBgn0001250,
  • PS 2,
  • aPS2,
  • alpha[[PS2]] integrin,
  • position-specific antigen 2,
  • alpha2Int,
  • PS2alpha,
  • alpha integrin,
  • PS2,
  • alphaPS2 Integrin,
  • CT27194,
  • integrin,
  • alphaPS2C,
  • alpha2 integrin,
  • alphaPS2-integrin,
  • Integrin alphaPS2 subunit

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85 Alleles

DB identifier Symbol Allele Class Organism
FBal0277323 if[Scer\UAS.cUa]   Drosophila melanogaster
FBal0089218 if[Delta.m8.hs]   Drosophila melanogaster
FBal0089192 if[L326] amorphic allele - genetic evidence Drosophila melanogaster
FBal0057255 if[K13] amorphic allele - genetic evidence Drosophila melanogaster
FBal0039415 if[+t39]   Drosophila melanogaster
FBal0141087 if[GOF.C.hs]   Drosophila melanogaster
FBal0089187 if[O11K] amorphic allele - genetic evidence Drosophila melanogaster
FBal0089211 if[2B1]   Drosophila melanogaster
FBal0089180 if[minigene]   Drosophila melanogaster
FBal0089217 if[+tBa]   Drosophila melanogaster
FBal0090410 if[DeltaGFFNR]   Drosophila melanogaster
FBal0039416 if[B2.1]   Drosophila melanogaster
FBal0141081 if[m8.alphaTub84B]   Drosophila melanogaster
FBal0141082 if[LOF.m8.hs]   Drosophila melanogaster
FBal0089189 if[N18R] amorphic allele - genetic evidence Drosophila melanogaster
FBal0089198 if[C3C] amorphic allele - genetic evidence Drosophila melanogaster
FBal0034808 if[MtnA.PG]   Drosophila melanogaster
FBal0089191 if[L6] amorphic allele - genetic evidence Drosophila melanogaster
FBal0089190 if[M2] amorphic allele - genetic evidence Drosophila melanogaster
FBal0138220 if[unspecified]   Drosophila melanogaster
FBal0089199 if[C2B]   Drosophila melanogaster
FBal0089202 if[9] amorphic allele - genetic evidence Drosophila melanogaster
FBal0089186 if[O17Q] amorphic allele - genetic evidence Drosophila melanogaster
FBal0089183 if[O9I] amorphic allele - genetic evidence Drosophila melanogaster
FBal0005582 if[N]   Drosophila melanogaster
FBal0005581 if[k27e] amorphic allele - genetic evidence, loss of function allele Drosophila melanogaster
FBal0098232 if[2]   Drosophila melanogaster
FBal0031511 if[A7] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0039420 if[C.hs]   Drosophila melanogaster
FBal0089185 if[O2] amorphic allele - genetic evidence Drosophila melanogaster

47 Clones

Secondary Identifier DB identifier
CK01.141D.C12 FBcl0418697
AT02663 FBcl0025229
CK02516 FBcl0059861
EP12451 FBcl0082521
EP11043 FBcl0082523
EK128057 FBcl0121306
EK144457 FBcl0121472
EK169019 FBcl0121538
EK212301 FBcl0121542
EK022016 FBcl0121550
EK207629 FBcl0121554
EK121424 FBcl0121558
EK197916 FBcl0121578
EK172858 FBcl0121582
EK098609 FBcl0121592
EK200634 FBcl0121600
EK137353 FBcl0121652
EK248554 FBcl0121656
EK165758 FBcl0123160
EK137949 FBcl0123194
GM12416 FBcl0146426
IP16723 FBcl0317965
IP16623 FBcl0317966
IP16523 FBcl0317967
IP16423 FBcl0303600
EC051786 FBcl0299048
EC051283 FBcl0299049
EC051778 FBcl0299050
EC055462 FBcl0299051
EC055912 FBcl0299052

14 Exons

DB identifier Symbol
FBgn0001250:14 if:14
FBgn0001250:11 if:11
FBgn0001250:10 if:10
FBgn0001250:9 if:9
FBgn0001250:8 if:8
FBgn0001250:7 if:7
FBgn0001250:6 if:6
FBgn0001250:5 if:5
FBgn0001250:4 if:4
FBgn0001250:3 if:3
FBgn0001250:2 if:2
FBgn0001250:1 if:1
FBgn0001250:13 if:13
FBgn0001250:12 if:12

4 Transcripts

DB identifier Gene
FBtr0074357 if
FBtr0301352 if
FBtr0301354 if
FBtr0301353 if

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074357-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301352-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301353-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301354-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074357-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301352-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301353-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301354-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32661 NCBI Entrez Gene identifiers FBgn0001250
58994 BioGRID FBgn0001250

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1955.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1499.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 786.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1292.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 588.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 154.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 454.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 488.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 259.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 320.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 341.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 501.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 919.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1019.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1087.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2224.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 855.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 336.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1206.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1477.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 701.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2973.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1228.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 263.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 280.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 665.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 612.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1032.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1011.0
FBgn0001250 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 791.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0001250:14_FBgn0001250:11 Drosophila melanogaster
intron_FBgn0001250:11_FBgn0001250:10 Drosophila melanogaster
intron_FBgn0001250:10_FBgn0001250:9 Drosophila melanogaster
intron_FBgn0001250:9_FBgn0001250:8 Drosophila melanogaster
intron_FBgn0001250:8_FBgn0001250:7 Drosophila melanogaster
intron_FBgn0001250:7_FBgn0001250:6 Drosophila melanogaster
intron_FBgn0001250:6_FBgn0001250:5 Drosophila melanogaster
intron_FBgn0001250:5_FBgn0001250:4 Drosophila melanogaster
intron_FBgn0001250:4_FBgn0001250:3 Drosophila melanogaster
intron_FBgn0001250:3_FBgn0001250:2 Drosophila melanogaster
intron_FBgn0001250:2_FBgn0001250:1 Drosophila melanogaster
intron_FBgn0001250:6_FBgn0001250:4 Drosophila melanogaster
intron_FBgn0001250:12_FBgn0001250:11 Drosophila melanogaster
intron_FBgn0001250:13_FBgn0001250:11 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage if none -0.034970435   19067489
Lipid storage if none 0.992994159   19067489
ERK signaling if ERK activation reduced weak   17086199
Cell morphology if Morphology np   14527345
Cell size and cell-cycle regulation (1) if none sp   16496002
Integrin adhesion if Round or flaky np   18166658
Mutant human huntingtin aggregation if Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) if Lethal np   20220848
Muscle morphogenesis and function (2) if Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) if Rounded muscles, undefined larval sarcomere morphology np   20220848
Heat nociception (1) if none -1.17   21074052
Heat nociception (1) if Developmentally lethal 0   21074052
Heart development and function (1) if none 1   20371351
Serratia marcescens infection (1) if none -0.22680412371134   19520911
Serratia marcescens infection (1) if none -0.0253164556962025   19520911
Notch pathway regulation (4) if Loss of bristles 3   19363474
Notch pathway regulation (4) if Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation if Increased P-JNK protein expression with PGN 3.18 15 min PGN induction 19893628
Notch pathway regulation (1) if Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) if none np en-GAL4 20493818
Notch pathway regulation (2) if Wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (3) if none np   20493818
Adiposity regulation (1) if none -0.343   20074523
Adiposity regulation (1) if none -0.074   20074523
RTK-Ras-ERK pathway regulation (1) if Decreased ERK phosphorylation after EGF stimulation -3.71 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) if none -1.43 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) if none 0.04 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) if none 0.45 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation if none -0.58   23263283
Muscle development and maintenance if Embryo lethal sp  

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