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Gene : alphaTub67C D. melanogaster

DB identifier  ? FBgn0087040 Secondary Identifier  ? CG8308
Name  ? alpha-Tubulin at 67C Source  FlyBase
  • synonyms:
  • Tubulin at 67C,
  • alphaTUB,
  • alphaTubulin67C,
  • FBgn0001067,
  • alpha4Tub67C,
  • alpha4-tubulin,
  • alpha tubulin,
  • Tub,
  • alpha4,
  • Tomaj,
  • FBgn0087040,
  • Fs(3)Sz22,
  • mum-tub67C,
  • alphaTub[67C],
  • tubulin,
  • aTub67C,
  • alpha67C,
  • ALPHA 67C,
  • FBan0008308,
  • alpha-Tub67C,
  • CG8308,
  • tubulin67C,
  • Tom,
  • alphaTub4,
  • 4t,
  • FBgn0001055,
  • Fs(3)Sz14,
  • Fs(3)Tom,
  • Female sterile (3) Kavar,
  • Fs(3)Tomaj,
  • alphaTub67C,
  • FBgn0004236,
  • T,
  • Fs(3)Kav,
  • Kavar,
  • Fs(3)Kavar,
  • DTA2,
  • D.m.ALPHA-67C,
  • alpha-Tubulin,
  • alpha-tubulin[4],
  • alphaT,
  • alpha-Tub,
  • alpha Tubulin 67C,
  • alpha4-t,
  • FBgn0003883,
  • tub67c,
  • alphatubulin,
  • alpha4t

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39 Alleles

DB identifier Symbol Allele Class Organism
FBal0212246 alphaTub67C[18c.Scer\UAS]   Drosophila melanogaster
FBal0138599 alphaTub67C[dsRNA.995-1491]   Drosophila melanogaster
FBal0138600 alphaTub67C[dsRNA.1530-2045]   Drosophila melanogaster
FBal0004766 alphaTub67C[kav-18c] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0004768 alphaTub67C[kav-21g] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0004767 alphaTub67C[kav-21l]   Drosophila melanogaster
FBal0198519 alphaTub67C[kav-rX21] loss of function allele Drosophila melanogaster
FBal0198520 alphaTub67C[kav-re11]   Drosophila melanogaster
FBal0198521 alphaTub67C[kav-re12]   Drosophila melanogaster
FBal0198522 alphaTub67C[kav-re22]   Drosophila melanogaster
FBal0198523 alphaTub67C[kav-re31]   Drosophila melanogaster
FBal0198524 alphaTub67C[+tVa]   Drosophila melanogaster
FBal0098573 alphaTub67C[P40]   Drosophila melanogaster
FBal0104379 alphaTub67C[P40Delta]   Drosophila melanogaster
FBal0278217 alphaTub67C[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0044538 alphaTub67C[Tom-4091] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0000009 alphaTub67C[2] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0033258 alphaTub67C[+t7]   Drosophila melanogaster
FBal0090808 alphaTub67C[RX1.1]   Drosophila melanogaster
FBal0089854 alphaTub67C[unspecified]   Drosophila melanogaster
FBal0044537 alphaTub67C[Tom-3a] cold sensitive antimorphic allele - genetic evidence Drosophila melanogaster
FBal0090806 alphaTub67C[RX2.2]   Drosophila melanogaster
FBal0090812 alphaTub67C[RE3.2]   Drosophila melanogaster
FBal0090811 alphaTub67C[RE3.3]   Drosophila melanogaster
FBal0000011 alphaTub67C[4] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0090814 alphaTub67C[RE2.1]   Drosophila melanogaster
FBal0090807 alphaTub67C[RX2.1]   Drosophila melanogaster
FBal0090805 alphaTub67C[RX3.1]   Drosophila melanogaster
FBal0090809 alphaTub67C[RP3.1]   Drosophila melanogaster
FBal0000008 alphaTub67C[1] hypomorphic allele - genetic evidence Drosophila melanogaster

42 Clones

Secondary Identifier DB identifier
GM01358 FBcl0139831
GM10287 FBcl0139835
GM08480 FBcl0139837
GM02046 FBcl0139841
GM03749 FBcl0139845
GM01218 FBcl0139847
GM01216 FBcl0139857
GM07582 FBcl0139859
GM32429 FBcl0145157
GM19241 FBcl0145160
GM13885 FBcl0145168
LD10607 FBcl0155984
LD06333 FBcl0155993
LD05857 FBcl0155994
LD32464 FBcl0169572
LD45977 FBcl0169582
RE44641 FBcl0195561
RE22956 FBcl0211590
GM21578 FBcl0354987
Dmel_neb_007856_0666_2355 FBcl0381754
Dmel_neb_010940_0148_2051 FBcl0381766
Dmel_neb_012004_0908_2301 FBcl0381751
Dmel_neb_007737_0678_1572 FBcl0381752
Dmel_neb_002216_0943_3714 FBcl0381753
Dmel_neb_006522_0127_3058 FBcl0381755
Dmel_neb_015371_0428_3171 FBcl0381756
Dmel_neb_013918_0119_2272 FBcl0381757
Dmel_neb_014136_0391_1145 FBcl0381758
Dmel_dig_020439_0676_2919 FBcl0381759
Dmel_neb_013126_0094_2149 FBcl0381760

2 Exons

DB identifier Symbol
FBgn0087040:1 alphaTub67C:1
FBgn0087040:2 alphaTub67C:2

1 Transcripts

DB identifier Gene
FBtr0076393 alphaTub67C

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076393-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076393-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39130 NCBI Entrez Gene identifiers FBgn0087040
64519 BioGRID FBgn0087040

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 52.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 52.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 129.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 122.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 73.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 45.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 112.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 49.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 290.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 26.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 36.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 63.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 63.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 100.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 18.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 200.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 74.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 49.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 72.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 71.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 101.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 21.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 138.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 176.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 42.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6543.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 439.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 126.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 112.0
FBgn0087040 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 50.0

1 Introns

DB identifier
Organism . Name
intron_FBgn0087040:1_FBgn0087040:2 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage alphaTub67C none -1.407945459   19067489
Lipid storage alphaTub67C none 0.210974952   19067489
ERK signaling alphaTub67C ERK activation reduced weak   17086199
Constitutive protein secretion and Golgi organization (1) alphaTub67C Decreased horseradish peroxidase protein expression sp   16452979
Muscle morphogenesis and function (1) alphaTub67C Lethal np   20220848
Muscle morphogenesis and function (1) alphaTub67C Lethal np   20220848
Serratia marcescens infection (1) alphaTub67C none -0.404761904761904   19520911
Notch pathway regulation (4) alphaTub67C Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) alphaTub67C Bristle morphology defects, notum malformation death sp   19363474
Self-renewal and differentiation in neural stem cells alphaTub67C GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, extremely increased neuroblast cell size without neuroblast loss, neuroblast unde sp   21549331
Self-renewal and differentiation in neural stem cells alphaTub67C GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) alphaTub67C Increased triglyceride expression 0.544   20074523
Adiposity regulation (2) alphaTub67C Lethal or developmental delay d/l   20074523
Adiposity regulation (3) alphaTub67C none 0.05   20074523
Adiposity regulation (4) alphaTub67C Lethal or developmental delay d/l   20074523
Adiposity regulation (5) alphaTub67C none -0.197   20074523
RTK-Ras-ERK pathway regulation (1) alphaTub67C Increased ERK phosphorylation after EGF stimulation 3.46 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) alphaTub67C none -1.08 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) alphaTub67C none -0.55 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) alphaTub67C none -0.31 10 minutes sSpitz stimulation 22028469
Wnt proteins secretion alphaTub67C none 0.2   22094269
Hippo pathway regulation alphaTub67C none -0.28   23263283
Muscle development and maintenance alphaTub67C Climbing defect sp  
Muscle maintenance alphaTub67C Climbing defect sp  
Glycosylation regulation (1) alphaTub67C none sp   21203496

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