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Gene : pygo D. melanogaster

DB identifier  ? FBgn0043900 Secondary Identifier  ? CG11518
Name  ? pygopus Source  FlyBase
  • synonyms:
  • Pygo,
  • FBgn0039853,
  • pyg,
  • BEST:LD21971,
  • anon-WO02077023.1,
  • CG11518,
  • FBgn0064198,
  • gammy legs,
  • FBan0011518,
  • unnamed,
  • pypo,
  • dPygo,
  • pNB5.2,
  • Pygopus,
  • FBgn0028951,
  • gam,
  • FBgn0043900,
  • Dm Pygo,
  • pygopous

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38 Alleles

DB identifier Symbol Allele Class Organism
FBal0221758 pygo[F78A]   Drosophila melanogaster
FBal0239127 pygo[T:Ivir\HA1]   Drosophila melanogaster
FBal0239128 pygo[Y748A.T:Ivir\HA1]   Drosophila melanogaster
FBal0178280 pygo[e01745]   Drosophila melanogaster
FBal0239129 pygo[V757E.T:Ivir\HA1]   Drosophila melanogaster
FBal0239130 pygo[A763E.T:Ivir\HA1]   Drosophila melanogaster
FBal0239131 pygo[Y748A.A763E.T:Ivir\HA1]   Drosophila melanogaster
FBal0239132 pygo[Y748A.F773E.T:Ivir\HA1]   Drosophila melanogaster
FBal0239133 pygo[L789A.T:Ivir\HA1]   Drosophila melanogaster
FBal0119700 pygo[EP1076]   Drosophila melanogaster
FBal0278559 pygo[GL00647]   Drosophila melanogaster
FBal0240995 pygo[677]   Drosophila melanogaster
FBal0240996 pygo[577]   Drosophila melanogaster
FBal0240997 pygo[11-3]   Drosophila melanogaster
FBal0191966 pygo[+tHa]   Drosophila melanogaster
FBal0135636 pygo[alphaTub84B.PK]   Drosophila melanogaster
FBal0138164 pygo[10]   Drosophila melanogaster
FBal0140971 pygo[dsRNA.cTa]   Drosophila melanogaster
FBal0138160 pygo[unspecified]   Drosophila melanogaster
FBal0140974 pygo[F107]   Drosophila melanogaster
FBal0140973 pygo[F15] loss of function allele Drosophila melanogaster
FBal0140972 pygo[F66]   Drosophila melanogaster
FBal0135635 pygo[130]   Drosophila melanogaster
FBal0138163 pygo[9]   Drosophila melanogaster
FBal0146871 pygo[S28] loss of function allele, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0191338 pygo[F99A.tHa]   Drosophila melanogaster
FBal0146872 pygo[S123] loss of function allele Drosophila melanogaster
FBal0197615 pygo[dsRNA.cMa]   Drosophila melanogaster
FBal0138162 pygo[Act5C.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0154710 pygo[mLoop1.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster

59 Clones

Secondary Identifier DB identifier
AT01724 FBcl0036675
EC32728 FBcl0071581
EP13324 FBcl0087447
EP17036 FBcl0087523
GH25362 FBcl0120353
GH28687 FBcl0120947
EK258325 FBcl0138660
EK084939 FBcl0138714
EK088602 FBcl0138770
EK092920 FBcl0138786
EK059822 FBcl0139894
EK092341 FBcl0140010
EK074526 FBcl0140570
EK138614 FBcl0141304
EK182902 FBcl0141332
EK090930 FBcl0141376
EK090232 FBcl0141406
EK182521 FBcl0141460
LD18280 FBcl0157370
LD16979 FBcl0157408
LD21971 FBcl0171454
RE45211 FBcl0216294
RE21684 FBcl0216800
RE46758 FBcl0216823
EC052466 FBcl0300609
EC051383 FBcl0300610
CK01.119A.H11 FBcl0430870
CK01.76C.H1 FBcl0430912
Dmel_neb_014041_0632_1263 FBcl0371642
CK01.121C.E7 FBcl0430760

3 Exons

DB identifier Symbol
FBgn0043900:3 pygo:3
FBgn0043900:2 pygo:2
FBgn0043900:1 pygo:1

1 Transcripts

DB identifier Gene
FBtr0085806 pygo

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085806-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085806-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43718 NCBI Entrez Gene identifiers FBgn0043900
68561 BioGRID FBgn0043900

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 351.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 411.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 395.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 255.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 354.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 375.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 328.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 374.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 303.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 365.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 392.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 230.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 332.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 459.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 351.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 296.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 363.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 219.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 431.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 321.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 624.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 413.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 180.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 322.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 340.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2036.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1759.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 655.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 685.0
FBgn0043900 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 573.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0043900:3_FBgn0043900:2 Drosophila melanogaster
intron_FBgn0043900:2_FBgn0043900:1 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage pygo none -0.021151818   19067489
Lipid storage pygo none -0.681136096   19067489
Neural outgrowth pygo Excess branching np   18604272
Wnt signaling pygo Decreased Wnt reporter activity -1.2   15817814
Cell size and cell-cycle regulation (1) pygo none sp   16496002
Cell size and cell-cycle regulation (1) pygo none sp   16496002
Dendrite pattern formation pygo none np   16547170
Muscle morphogenesis and function (1) pygo Lethal np   20220848
Muscle morphogenesis and function (1) pygo Lethal np   20220848
Muscle morphogenesis and function (2) pygo Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) pygo Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) pygo none -0.4   21074052
Heart development and function (1) pygo none 1   20371351
Serratia marcescens infection (1) pygo none -0.642857142857142   19520911
Serratia marcescens infection (1) pygo none 0.153846153846153   19520911
Notch pathway regulation (4) pygo Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) pygo Notum malformation death 9   19363474
Muscle assembly and maintenance pygo Muscles spread, myosin filaments striated, actin filaments lack striation severe   18359903
Self-renewal and differentiation in neural stem cells pygo Ganglion mother cell larger cell size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells pygo Neuroblast cell shape, ganglion mother cell larger cell size, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Notch pathway regulation (1) pygo Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) pygo none np C96-GAL4 20493818
Notch pathway regulation (2) pygo Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) pygo Downregulation of Notch pathway; adult wing margin: notches sp en-GAL4 20493818
Notch pathway regulation (2) pygo Downregulation of Notch pathway; wing disc NRE:EGFP: down, broader; wing disc myrRFP: accumulation, reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) pygo Downregulation of Notch pathway; wing disc NRE:EGFP: down; wing disc myrRFP: reduced sp en-GAL4 20493818
Notch pathway regulation (3) pygo none np   20493818
Adiposity regulation (1) pygo none 0.068   20074523
Wnt proteins secretion pygo Downregulation of Wg pathway -6.1   22094269
Hippo pathway regulation pygo none 0.21   23263283

0 Submissions