Genomics
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9 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0286427 | RpS3A[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286428 | RpS3A[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0011966 | RpS3A[57g] | Drosophila melanogaster | |
| FBal0083249 | RpS3A[hs.PR] | Drosophila melanogaster | |
| FBal0083250 | RpS3A[a.hs] | Drosophila melanogaster | |
| FBal0208388 | RpS3A[GD8638] | Drosophila melanogaster | |
| FBal0208389 | RpS3A[GD16970] | Drosophila melanogaster | |
| FBal0231008 | RpS3A[KK100950] | Drosophila melanogaster | |
| FBal0273069 | RpS3A[NIG.2168R] | Drosophila melanogaster |
986 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0017545:5 | RpS3A:5 |
| FBgn0017545:4 | RpS3A:4 |
| FBgn0017545:7 | RpS3A:7 |
| FBgn0017545:6 | RpS3A:6 |
| FBgn0017545:3 | RpS3A:3 |
| FBgn0017545:2 | RpS3A:2 |
| FBgn0017545:1 | RpS3A:1 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0089175-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0089176-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0308296-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0089175-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0089176-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0308296-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Metabolism of RNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Peptide chain elongation,
- Transport of the SLBP independent Mature mRNA,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Transport of Mature Transcript to Cytoplasm,
- Cleavage of Growing Transcript in the Termination Region,
- Processing of Intronless Pre-mRNAs,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Eukaryotic Translation Elongation,
- Recycling of eIF2:GDP,
- SRP-dependent cotranslational protein targeting to membrane,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- RNA Polymerase II Transcription Elongation,
- Cap-dependent Translation Initiation,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Translation initiation complex formation,
- Transcription,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Post-Elongation Processing of Intronless pre-mRNA,
- Eukaryotic Translation Termination,
- Processing of Capped Intronless Pre-mRNA,
- Formation of a pool of free 40S subunits,
- RNA Polymerase II Transcription,
- RNA Polymerase II Transcription Termination,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Formation of RNA Pol II elongation complex,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Metabolism of mRNA,
- Metabolism of proteins,
- Transport of the SLBP Dependant Mature mRNA,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- mRNA Processing,
- RNA Polymerase II Transcription Initiation,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Nonsense-Mediated Decay,
- Elongation arrest and recovery,
- Translation,
- mRNA Capping,
- Formation of the Early Elongation Complex,
- Eukaryotic Translation Initiation,
- Ribosomal scanning and start codon recognition,
- RNA Polymerase II Pre-transcription Events,
- RNA Polymerase II Promoter Escape,
- Post-Elongation Processing of the Transcript,
- SLBP independent Processing of Histone Pre-mRNAs,
- Gene Expression,
- 3' -UTR-mediated translational regulation,
- Processing of Capped Intron-Containing Pre-mRNA,
- Transport of Mature mRNAs Derived from Intronless Transcripts
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43768 | NCBI Entrez Gene identifiers | FBgn0017545 |
| 68606 | BioGRID | FBgn0017545 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
6 Introns
37 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS3A | Increased lipid droplet area | 3.217129101 | 19067489 | |
| Lipid storage | RpS3A | Increased lipid droplet area | 2.091892558 | 19067489 | |
| Drosophila C virus infection | RpS3A | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpS3A | Binucleate cells with decreased viability | weak | 15547975 | |
| Drosophila C virus infection | RpS3A | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS3A | Decreased Hedgehog reporter activity | -2.32 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS3A | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS3A | Decreased G2 DNA content | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | RpS3A | none | sp | 16496002 | |
| Candida albicans phagocytosis (1) | RpS3A | none | np | 16336044 | |
| Influenza replication | RpS3A | Decreased Influenza replication | -1.68/-2.85 | 18615016 | |
| Lipid storage | RpS3A | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Microtubule assembly and organization | RpS3A | none | np | 18463163 | |
| Combinatorial effect with methyl methanesulphonate (2) | RpS3A | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Muscle morphogenesis and function (1) | RpS3A | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS3A | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS3A | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Heat nociception (1) | RpS3A | none | -0.5 | 21074052 | |
| Heart development and function (1) | RpS3A | Embryonic lethal or no offspring | 0 | 20371351 | |
| Heart development and function (1) | RpS3A | Embryonic lethal or no offspring | 0 | 20371351 | |
| Heart development and function (1) | RpS3A | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | RpS3A | none | -0.28125 | 19520911 | |
| Notch pathway regulation (4) | RpS3A | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS3A | Completely lethal (before pupal) | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | RpS3A | Increased P-JNK protein expression with PGN | 3.26 | 60 min PGN induction | 19893628 |
| Hh pathway regulation | RpS3A | Downregulation of Hh pathway | -0.667184467490484 | 17903264 | |
| Hh pathway regulation | RpS3A | Downregulation of Hh pathway | -0.573144361344501 | 17903264 | |
| Adiposity regulation (1) | RpS3A | none | 1.023 | 20074523 | |
| Blood cell homeostasis regulation (1) | RpS3A | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | RpS3A | none | np | 20540764 |
