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Gene : Su(var)205 D. melanogaster
DB identifier  ? FBgn0003607 Secondary Identifier  ? CG8409
Name  ? Suppressor of variegation 205 Source  FlyBase
  • synonyms:
  • HP1,
  • FBan0008409,
  • SU(VAR)205,
  • Su-var(2)5,
  • Heterochromatin protein-1,
  • E(var)29A,
  • Heterochromatic Protein 1a,
  • CG8409,
  • C1A9-nuclear-antigen,
  • Heterochromatin Protein 1,
  • HP1-VS,
  • dHP-1a,
  • Su(var),
  • HP1alpha,
  • Heterochromatin Protein 1A,
  • HP-1,
  • Su(Var)2-5,
  • dHP1,
  • DmHP1,
  • FBgn0003607,
  • Suvar(2)5,
  • heterochromatic protein,
  • Su[Var]205,
  • Su(var)29A,
  • DmHP-1,
  • Suvar2-5,
  • CBX5,
  • heterochromatin-protein-1,
  • Su(var)2-501,
  • Su(var)[205],
  • HP1A,
  • Su(var)2-05,
  • heterochromatin-binding protein,
  • E(var)29,
  • Histone Protein 1,
  • Suppressor of variegation 205
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Lists
This Gene is in 2 lists:
Fly classI (1496)
Fly classIb (585)

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83 Alleles

DB identifier Symbol Allele Class Organism
FBal0266231 Su(var)205[GL00531]   Drosophila melanogaster
FBal0212197 Su(var)205[dsRNA.Sym.Scer\UAS]   Drosophila melanogaster
FBal0257177 Su(var)205[HMS00278]   Drosophila melanogaster
FBal0256742 Su(var)205[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0181382 Su(var)205[c06825]   Drosophila melanogaster
FBal0243479 Su(var)205[g.T:Disc\RFP]   Drosophila melanogaster
FBal0243480 Su(var)205[g.T:Avic\GFP]   Drosophila melanogaster
FBal0030285 Su(var)205[hs.PE]   Drosophila melanogaster
FBal0121887 Su(var)205[hs.PP]   Drosophila melanogaster
FBal0121888 Su(var)205[SSS89.90.91AAA.hs]   Drosophila melanogaster
FBal0121889 Su(var)205[SSS102.103.104.EEE.hs]   Drosophila melanogaster
FBal0121890 Su(var)205[SSS102.103.104.AAA.hs]   Drosophila melanogaster
FBal0121891 Su(var)205[SS15.202AA.hs]   Drosophila melanogaster
FBal0121892 Su(var)205[S202E.hs]   Drosophila melanogaster
FBal0121893 Su(var)205[S202A.hs]   Drosophila melanogaster
FBal0121894 Su(var)205[S15E.hs]   Drosophila melanogaster
FBal0121895 Su(var)205[S15E.S202A.hs]   Drosophila melanogaster
FBal0121896 Su(var)205[S15A.hs]   Drosophila melanogaster
FBal0144512 Su(var)205[1.9kb]   Drosophila melanogaster
FBal0150593 Su(var)205[+tSa]   Drosophila melanogaster
FBal0135786 Su(var)205[1097]   Drosophila melanogaster
FBal0095556 Su(var)205[03]   Drosophila melanogaster
FBal0117637 Su(var)205[205]   Drosophila melanogaster
FBal0016506 Su(var)205[4]   Drosophila melanogaster
FBal0135784 Su(var)205[1545]   Drosophila melanogaster
FBal0016503 Su(var)205[1]   Drosophila melanogaster
FBal0135787 Su(var)205[1009]   Drosophila melanogaster
FBal0016504 Su(var)205[2]   Drosophila melanogaster
FBal0135785 Su(var)205[1207]   Drosophila melanogaster
FBal0175791 Su(var)205[P4]   Drosophila melanogaster

61 Clones

Secondary Identifier DB identifier
DPiM_LD10408 FBcl0741980
UUGC0877 FBcl0004879
EK200932 FBcl0045516
EK060439 FBcl0046750
EK147260 FBcl0046766
EK161759 FBcl0046772
EK067920 FBcl0046804
bs27f09 FBcl0048989
EC39504 FBcl0063775
EC14346 FBcl0063783
EN04616 FBcl0093011
EN10701 FBcl0093041
EN12846 FBcl0093047
LD10408 FBcl0157698
LD14227 FBcl0157721
LD32004 FBcl0171867
LD23051 FBcl0171874
LP12401 FBcl0186221
RE48985 FBcl0217396
RE42891 FBcl0217874
RE17121 FBcl0217886
RE16004 FBcl0217896
RE25556 FBcl0217910
RE21970 FBcl0217916
RE16682 FBcl0217917
RE18120 FBcl0217924
RE36537 FBcl0217927
RE05167 FBcl0217932
RE66735 FBcl0217933
RE42128 FBcl0217935

6 Exons

DB identifier Symbol
FBgn0003607:2 Su(var)205:2
FBgn0003607:1 Su(var)205:1
FBgn0003607:3 Su(var)205:3
FBgn0003607:6 Su(var)205:6
FBgn0003607:4 Su(var)205:4
FBgn0003607:5 Su(var)205:5

2 Transcripts

DB identifier Gene
FBtr0079636 Su(var)205
FBtr0079635 Su(var)205

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079635-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0079636-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079635-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079636-3-prime-utr Drosophila melanogaster

Interactions

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Other

2 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
34119 NCBI Entrez Gene identifiers FBgn0003607
60248 BioGRID FBgn0003607

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 5970.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 6483.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 4812.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 5924.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5386.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 5131.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2941.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 5802.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3998.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 7250.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 7074.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 7102.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 9791.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 7552.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 8134.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 7466.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 5210.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4390.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 9585.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 5116.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 7560.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 5532.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 4394.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3219.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 3899.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8010.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 8550.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 10663.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 8652.0
FBgn0003607 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 8553.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0003607:6_FBgn0003607:4 Drosophila melanogaster
intron_FBgn0003607:4_FBgn0003607:3 Drosophila melanogaster
intron_FBgn0003607:3_FBgn0003607:2 Drosophila melanogaster
intron_FBgn0003607:2_FBgn0003607:1 Drosophila melanogaster
intron_FBgn0003607:5_FBgn0003607:3 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Su(var)205 Decreased lipid droplet area -1.85908779   19067489
Lipid storage Su(var)205 Decreased lipid droplet area -2.42784401   19067489
Cell size and cell-cycle regulation (1) Su(var)205 none sp   16496002
Dendrite pattern formation Su(var)205 none np   16547170
Mitochondrial biogenesis and function Su(var)205 Decreased mitochondrial citrate synthase activity 0.652   18042644
Muscle morphogenesis and function (1) Su(var)205 Weak flyer np   20220848
Muscle morphogenesis and function (1) Su(var)205 Weak flyer np   20220848
Heat nociception (1) Su(var)205 none -1.17   21074052
Heat nociception (1) Su(var)205 none -1.17   21074052
Heart development and function (1) Su(var)205 Embryonic lethal or no offspring 0.5   20371351
Heart development and function (1) Su(var)205 none 1   20371351
Heart development and function (2) Su(var)205 Decreased viability 3.06   20371351
Serratia marcescens infection (1) Su(var)205 none 0.779220779220779   19520911
Notch pathway regulation (4) Su(var)205 Loss of bristles 1   19363474
Notch pathway regulation (4) Su(var)205 Planar polarity defects 2   19363474
Self-renewal and differentiation in neural stem cells Su(var)205 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with larger neuroblast cell size, neuroblast underprolifer sp   21549331
Self-renewal and differentiation in neural stem cells Su(var)205 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with larger neuroblast cell si sp   21549331
Adiposity regulation (1) Su(var)205 none 0.02   20074523
Hippo pathway regulation Su(var)205 none 0.09   23263283
Glycosylation regulation (1) Su(var)205 none sp   21203496

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