Genomics
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11 Alleles
DB identifier | Symbol | Allele Class | Organism |
---|---|---|---|
FBal0263549 | CycC[GE22979] | Drosophila melanogaster | |
FBal0263550 | CycC[Scer\UAS.cLa] | Drosophila melanogaster | |
FBal0282539 | CycC[dsRNA.Scer\UAS] | Drosophila melanogaster | |
FBal0282540 | CycC[Scer\UAS.T:Ivir\HA1] | Drosophila melanogaster | |
FBal0257759 | CycC[HMS01095] | Drosophila melanogaster | |
FBal0055184 | CycC[hs.PR] | Drosophila melanogaster | |
FBal0184258 | CycC[cKa] | Drosophila melanogaster | |
FBal0184259 | CycC[a.cKa] | Drosophila melanogaster | |
FBal0218349 | CycC[Y5] | amorphic allele - molecular evidence, amorphic allele - genetic evidence | Drosophila melanogaster |
FBal0206707 | CycC[GD12193] | Drosophila melanogaster | |
FBal0206708 | CycC[GD17120] | Drosophila melanogaster |
38 Clones
2 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0083010-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0083010-3-prime-utr | Drosophila melanogaster |
Other
35 Pathways
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- Transcriptional Regulation of White Adipocyte Differentiation,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Signaling by TGF-beta Receptor Complex in Cancer,
- TGFBR1 LBD Mutants in Cancer,
- TGF-beta receptor signaling activates SMADs,
- Signaling by TGF-beta Receptor Complex,
- FBXW7 Mutants and NOTCH1 in Cancer,
- Signaling by NOTCH1,
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant,
- TGFBR1 KD Mutants in Cancer,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- TGFBR2 Kinase Domain Mutants in Cancer,
- Signaling by Activin,
- Signaling by NOTCH1 in Cancer,
- Signaling Pathways,
- Signaling by NOTCH1 HD Domain Mutants in Cancer,
- SMAD4 MH2 Domain Mutants in Cancer,
- Disease,
- Loss of Function of TGFBR2 in Cancer,
- Signaling by NOTCH,
- Generic Transcription Pathway,
- Gene Expression,
- Loss of Function of SMAD2/3 in Cancer,
- Developmental Biology,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- Loss of Function of TGFBR1 in Cancer,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Loss of Function of SMAD4 in Cancer,
- Signaling by NODAL
2 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
41801 | NCBI Entrez Gene identifiers | FBgn0004597 |
66871 | BioGRID | FBgn0004597 |
11 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
Swiss-Prot data set | http://ca.expasy.org/sprot |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
30 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | CycC | none | -0.161528259 | 19067489 | |
Lipid storage | CycC | none | 0.044238771 | 19067489 | |
Cell size and cell-cycle regulation (1) | CycC | none | sp | 16496002 | |
Dendrite pattern formation | CycC | none | np | 16547170 | |
Muscle morphogenesis and function (1) | CycC | none | np | 20220848 | |
Muscle morphogenesis and function (1) | CycC | none | np | 20220848 | |
Muscle morphogenesis and function (1) | CycC | none | np | 20220848 | |
Muscle morphogenesis and function (1) | CycC | Weak flyer | np | 20220848 | |
Heat nociception (1) | CycC | none | -1.17 | 21074052 | |
Heat nociception (1) | CycC | none | -0.36 | 21074052 | |
Heart development and function (1) | CycC | none | 1 | 20371351 | |
Serratia marcescens infection (1) | CycC | none | 1.0379746835443 | 19520911 | |
Serratia marcescens infection (1) | CycC | none | -0.123711340206185 | 19520911 | |
Notch pathway regulation (4) | CycC | Notum malformation migration, overproliferation | sp | 19363474 | |
Notch pathway regulation (4) | CycC | Loss of bristles, bristle morphology defects, notum malformation death, overproliferation | sp | 19363474 | |
Notch pathway regulation (4) | CycC | Loss of bristles, bristle morphology defects, notum malformation death | sp | 19363474 | |
Notch pathway regulation (4) | CycC | Completely lethal (before pupal) | sp | 19363474 | |
G2-M DNA damage checkpoint regulation (2) | CycC | Increased histone H3 phosphorylation with bleocin | 60.08 | with bleocin | 21205937 |
G2-M DNA damage checkpoint regulation (2) | CycC | Increased histone H3 phosphorylation with doxorubicin | 65.56 | with doxorubicin | 21205937 |
G2-M DNA damage checkpoint regulation (2) | CycC | Increased histone H3 phosphorylation with etoposide | 56.66 | with etoposide | 21205937 |
G2-M DNA damage checkpoint regulation (2) | CycC | Increased histone H3 phosphorylation after X-ray exposure | 78.02 | X-ray exposure | 21205937 |
Adiposity regulation (1) | CycC | none | -0.175 | 20074523 | |
Adiposity regulation (1) | CycC | none | 0.152 | 20074523 | |
Vaccinia virus infection | CycC | none | sp | 20585561 | |
RTK-Ras-ERK pathway regulation (1) | CycC | none | -1.45 | 0 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (1) | CycC | none | -0 | 10 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | CycC | none | 1.17 | 30 minutes sSpitz stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | CycC | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.68 | 10 minutes sSpitz stimulation | 22028469 |
Hippo pathway regulation | CycC | none | 1.73 | 23263283 | |
Glycosylation regulation (1) | CycC | Decreased Chp protein expression | np | 21203496 |