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Gene : CycC D. melanogaster

DB identifier  ? FBgn0004597 Secondary Identifier  ? CG7281
Name  ? Cyclin C Source  FlyBase
  • synonyms:
  • CG1C_DROME,
  • CYCC,
  • Cln3,
  • CG7281,
  • cyclin C,
  • Cyc-C,
  • DmcycC,
  • FBan0007281,
  • dCycC,
  • SRB11,
  • FBgn0004597,
  • cyclinC,
  • dTRAP33

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11 Alleles

DB identifier Symbol Allele Class Organism
FBal0263549 CycC[GE22979]   Drosophila melanogaster
FBal0263550 CycC[Scer\UAS.cLa]   Drosophila melanogaster
FBal0282539 CycC[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0282540 CycC[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0257759 CycC[HMS01095]   Drosophila melanogaster
FBal0055184 CycC[hs.PR]   Drosophila melanogaster
FBal0184258 CycC[cKa]   Drosophila melanogaster
FBal0184259 CycC[a.cKa]   Drosophila melanogaster
FBal0218349 CycC[Y5] amorphic allele - molecular evidence, amorphic allele - genetic evidence Drosophila melanogaster
FBal0206707 CycC[GD12193]   Drosophila melanogaster
FBal0206708 CycC[GD17120]   Drosophila melanogaster

38 Clones

Secondary Identifier DB identifier
DPiM_LD35705 FBcl0742068
AT03546 FBcl0041105
EK200455 FBcl0054948
EK134211 FBcl0055022
bs38f12 FBcl0057427
CK01810 FBcl0060539
EN17607 FBcl0101285
EN16051 FBcl0101305
LD44289 FBcl0175940
LD37489 FBcl0175941
LD42372 FBcl0175943
LD35705 FBcl0175946
LD40529 FBcl0175962
LD28187 FBcl0175963
LD40426 FBcl0175971
RE43093 FBcl0228980
RE71884 FBcl0229040
Dmel_dig_015466_0685_3119 FBcl0369248
FGM226A07 FBcl0391110
570010 FBcl0439768
RP003168316 FBcl0537623
RP003059684 FBcl0537626
RP003552070 FBcl0537631
RP003025054 FBcl0537634
RP003364570 FBcl0537635
RP003458343 FBcl0537637
RP003420911 FBcl0537638
RP003603561 FBcl0537640
RP003600124 FBcl0537641
RP003428888 FBcl0537644

2 Exons

DB identifier Symbol
FBgn0004597:2 CycC:2
FBgn0004597:1 CycC:1

1 Transcripts

DB identifier Gene
FBtr0083010 CycC

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083010-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083010-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41801 NCBI Entrez Gene identifiers FBgn0004597
66871 BioGRID FBgn0004597

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 318.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 295.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 225.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 426.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 371.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 284.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 240.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 231.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 235.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 296.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 272.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 241.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 192.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 349.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 256.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 191.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 276.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 365.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 231.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 357.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 325.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 352.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 200.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 318.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 214.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 696.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 725.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 592.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 528.0
FBgn0004597 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 412.0

1 Introns

DB identifier
Organism . Name
intron_FBgn0004597:2_FBgn0004597:1 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage CycC none -0.161528259   19067489
Lipid storage CycC none 0.044238771   19067489
Cell size and cell-cycle regulation (1) CycC none sp   16496002
Dendrite pattern formation CycC none np   16547170
Muscle morphogenesis and function (1) CycC none np   20220848
Muscle morphogenesis and function (1) CycC none np   20220848
Muscle morphogenesis and function (1) CycC none np   20220848
Muscle morphogenesis and function (1) CycC Weak flyer np   20220848
Heat nociception (1) CycC none -1.17   21074052
Heat nociception (1) CycC none -0.36   21074052
Heart development and function (1) CycC none 1   20371351
Serratia marcescens infection (1) CycC none 1.0379746835443   19520911
Serratia marcescens infection (1) CycC none -0.123711340206185   19520911
Notch pathway regulation (4) CycC Notum malformation migration, overproliferation sp   19363474
Notch pathway regulation (4) CycC Loss of bristles, bristle morphology defects, notum malformation death, overproliferation sp   19363474
Notch pathway regulation (4) CycC Loss of bristles, bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) CycC Completely lethal (before pupal) sp   19363474
G2-M DNA damage checkpoint regulation (2) CycC Increased histone H3 phosphorylation with bleocin 60.08 with bleocin 21205937
G2-M DNA damage checkpoint regulation (2) CycC Increased histone H3 phosphorylation with doxorubicin 65.56 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) CycC Increased histone H3 phosphorylation with etoposide 56.66 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) CycC Increased histone H3 phosphorylation after X-ray exposure 78.02 X-ray exposure 21205937
Adiposity regulation (1) CycC none -0.175   20074523
Adiposity regulation (1) CycC none 0.152   20074523
Vaccinia virus infection CycC none sp   20585561
RTK-Ras-ERK pathway regulation (1) CycC none -1.45 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) CycC none -0 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CycC none 1.17 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CycC Increased ERK phosphorylation after sSpitz and EGF stimulation 1.68 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation CycC none 1.73   23263283
Glycosylation regulation (1) CycC Decreased Chp protein expression np   21203496

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