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Gene : eIF3-S8 D. melanogaster

DB identifier  ? FBgn0034258 Secondary Identifier  ? CG4954
Name  ? eIF3-S8 Source  FlyBase
  • synonyms:
  • FBgn0034258,
  • CG4954,
  • eIF3-s8,
  • FBan0004954

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22 Alleles

DB identifier Symbol Allele Class Organism
FBal0159283 eIF3-S8[EY11279]   Drosophila melanogaster
FBal0159284 eIF3-S8[EY07713]   Drosophila melanogaster
FBal0141165 eIF3-S8[DG14606]   Drosophila melanogaster
FBal0141155 eIF3-S8[14F06Y-21]   Drosophila melanogaster
FBal0141148 eIF3-S8[14F06Y-28]   Drosophila melanogaster
FBal0141149 eIF3-S8[14F06Y-27]   Drosophila melanogaster
FBal0141150 eIF3-S8[14F06Y-26]   Drosophila melanogaster
FBal0141151 eIF3-S8[14F06Y-25]   Drosophila melanogaster
FBal0141152 eIF3-S8[14F06Y-24]   Drosophila melanogaster
FBal0141153 eIF3-S8[14F06Y-23]   Drosophila melanogaster
FBal0141154 eIF3-S8[14F06Y-22]   Drosophila melanogaster
FBal0141156 eIF3-S8[14F06Y-20]   Drosophila melanogaster
FBal0141157 eIF3-S8[14F06Y-19]   Drosophila melanogaster
FBal0141158 eIF3-S8[14F06Y-18]   Drosophila melanogaster
FBal0141159 eIF3-S8[14F06W-10]   Drosophila melanogaster
FBal0141160 eIF3-S8[14F06W-09]   Drosophila melanogaster
FBal0141161 eIF3-S8[14F06W-08]   Drosophila melanogaster
FBal0141162 eIF3-S8[14F06W-07]   Drosophila melanogaster
FBal0141163 eIF3-S8[14F06W-06]   Drosophila melanogaster
FBal0141164 eIF3-S8[14F06W-05]   Drosophila melanogaster
FBal0209474 eIF3-S8[GD11485]   Drosophila melanogaster
FBal0221904 eIF3-S8[CB-0470-3]   Drosophila melanogaster

318 Clones

Secondary Identifier DB identifier
EK053938 FBcl0030386
UUGC0633 FBcl0006399
AT13081 FBcl0023065
AT16243 FBcl0023071
AT14662 FBcl0023099
AT16916 FBcl0023101
EK230956 FBcl0026340
EK223808 FBcl0026396
EK205546 FBcl0026610
EK203806 FBcl0026618
EK278342 FBcl0026676
EK135241 FBcl0026682
EK307357 FBcl0026688
EK254742 FBcl0026696
GH21728 FBcl0119815
GH05913 FBcl0119897
GH05340 FBcl0119903
GH04993 FBcl0119907
GH25581 FBcl0119917
GH06591 FBcl0119919
GH11754 FBcl0119927
GH05245 FBcl0119935
GH17395 FBcl0119953
GH24969 FBcl0119955
GH15040 FBcl0119957
GH12741 FBcl0119973
GH04771 FBcl0119981
EK302559 FBcl0138648
EK094441 FBcl0138734
EK045722 FBcl0138848

6 Exons

DB identifier Symbol
FBgn0034258:2 eIF3-S8:2
FBgn0034258:3 eIF3-S8:3
FBgn0034258:5 eIF3-S8:5
FBgn0034258:1 eIF3-S8:1
FBgn0034258:4 eIF3-S8:4
FBgn0034258:6 eIF3-S8:6

2 Transcripts

DB identifier Gene
FBtr0086836 eIF3-S8
FBtr0340269 eIF3-S8

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086836-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340269-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086836-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340269-3-prime-utr Drosophila melanogaster

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43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37005 NCBI Entrez Gene identifiers FBgn0034258
62691 BioGRID FBgn0034258

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3536.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4315.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3002.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4388.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4080.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3114.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3649.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4132.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3726.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3235.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3816.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2024.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2518.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3824.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4547.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2819.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3320.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3066.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 4669.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3327.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3487.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3797.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2128.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1970.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2262.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4396.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4532.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 4438.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 3299.0
FBgn0034258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3855.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0034258:2_FBgn0034258:3 Drosophila melanogaster
intron_FBgn0034258:3_FBgn0034258:5 Drosophila melanogaster
intron_FBgn0034258:1_FBgn0034258:3 Drosophila melanogaster
intron_FBgn0034258:3_FBgn0034258:4 Drosophila melanogaster
intron_FBgn0034258:4_FBgn0034258:6 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eIF3-S8 Increased lipid droplet area 3.0394555   19067489
Lipid storage eIF3-S8 Increased lipid droplet area 3.428291729   19067489
Cytokinesis regulation eIF3-S8 Binucleate cells weak   15547975
Constitutive protein secretion and Golgi organization (1) eIF3-S8 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) eIF3-S8 none sp   16496002
Influenza replication eIF3-S8 Decreased Influenza replication -1.61/-3.21   18615016
Mitochondrial biogenesis and function eIF3-S8 Increased mitochondrial citrate synthase activity, decreased viability 1.281   18042644
Lipid storage eIF3-S8 Normal/larger sized lipid droplets, highly condensed strong   18408709
Muscle morphogenesis and function (1) eIF3-S8 Lethal np   20220848
Muscle morphogenesis and function (3) eIF3-S8 Split myofibril, fading Z-line np   20220848
Heat nociception (1) eIF3-S8 Developmentally lethal -1.17   21074052
Heat nociception (1) eIF3-S8 none 0.69   21074052
Heart development and function (1) eIF3-S8 Larval lethal 0.25   20371351
Serratia marcescens infection (1) eIF3-S8 none -1.44680851063829   19520911
Serratia marcescens infection (1) eIF3-S8 none 0.238095238095238   19520911
Notch pathway regulation (4) eIF3-S8 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) eIF3-S8 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (1) eIF3-S8 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) eIF3-S8 none -1   20074523
Adiposity regulation (1) eIF3-S8 none 0.136   20074523
RTK-Ras-ERK pathway regulation (1) eIF3-S8 Decreased ERK phosphorylation after EGF stimulation -3.81 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eIF3-S8 Decreased ERK phosphorylation after EGF stimulation -3.28 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF3-S8 none 0.15 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF3-S8 none 1.03 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion eIF3-S8 Upregulation of Wg pathway 3.6   22094269
Hippo pathway regulation eIF3-S8 none 1.36   23263283

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