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Gene : hep D. melanogaster

DB identifier  ? FBgn0010303 Secondary Identifier  ? CG4353
Name  ? hemipterous Source  FlyBase
  • synonyms:
  • l(1)G0208,
  • JNK-Kinase,
  • Mitogen-activated protein kinase kinase 7,
  • CG4353,
  • hem,
  • MAP2K7,
  • MKK7,
  • D-MKK7,
  • FBan0004353,
  • Hemipterous,
  • HEP,
  • l(1)G0107,
  • JNKK,
  • JNK kinase,
  • hep/JNKK,
  • FBgn0040188,
  • hp,
  • DMKK7,
  • HEP/MKK7,
  • hrp,
  • Hempiterous,
  • FBgn0030446,
  • DJNKK,
  • l(1)7P1,
  • CG2190,
  • FBgn0029076,
  • FBgn0013490,
  • DHEP/MKK7,
  • MAPKK,
  • FBgn0010303

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48 Alleles

DB identifier Symbol Allele Class Organism
FBal0243038 hep[NIG.2190R]   Drosophila melanogaster
FBal0269068 hep[NIG.4353R]   Drosophila melanogaster
FBal0179536 hep[GG01725]   Drosophila melanogaster
FBal0284406 hep[Scer\UAS.cUa]   Drosophila melanogaster
FBal0179535 hep[f02941]   Drosophila melanogaster
FBal0159166 hep[c02950]   Drosophila melanogaster
FBal0151866 hep[G0390]   Drosophila melanogaster
FBal0260277 hep[KK116295]   Drosophila melanogaster
FBal0045850 hep[r45]   Drosophila melanogaster
FBal0045851 hep[r51]   Drosophila melanogaster
FBal0005438 hep[1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0098235 hep[CA]   Drosophila melanogaster
FBal0102654 hep[G0107]   Drosophila melanogaster
FBal0103759 hep[G0208]   Drosophila melanogaster
FBal0215664 hep[699]   Drosophila melanogaster
FBal0045847 hep[Ubi-p63E.PG]   Drosophila melanogaster
FBal0045848 hep[hs.PG]   Drosophila melanogaster
FBal0031574 hep[7P1]   Drosophila melanogaster
FBal0065841 hep[rh1]   Drosophila melanogaster
FBal0098728 hep[H81]   Drosophila melanogaster
FBal0098730 hep[H49]   Drosophila melanogaster
FBal0189892 hep[v75]   Drosophila melanogaster
FBal0159165 hep[dsRNA.cSa]   Drosophila melanogaster
FBal0065838 hep[rh99]   Drosophila melanogaster
FBal0065839 hep[rh8]   Drosophila melanogaster
FBal0147101 hep[dsRNA.cCa]   Drosophila melanogaster
FBal0065842 hep[rh19]   Drosophila melanogaster
FBal0104605 hep[unspecified]   Drosophila melanogaster
FBal0045849 hep[r39]   Drosophila melanogaster
FBal0175650 hep[dsRNA.cIa]   Drosophila melanogaster

58 Clones

Secondary Identifier DB identifier
DPiM_FI03256 FBcl0741728
EP12105 FBcl0082263
EN16653 FBcl0096625
EN03722 FBcl0096637
EN08049 FBcl0096645
GH01858 FBcl0119409
EK171605 FBcl0124716
EK144442 FBcl0124718
EK213563 FBcl0124722
EK210751 FBcl0124730
EK259044 FBcl0124738
EK164525 FBcl0124742
EK101353 FBcl0124762
EK132761 FBcl0124764
EK122122 FBcl0124772
LD02655 FBcl0151871
LD02714 FBcl0157013
LD46661 FBcl0170942
LD26151 FBcl0170957
LP17496 FBcl0185502
LP10004 FBcl0185510
LP19975 FBcl0185520
RE49105 FBcl0193746
RE50877 FBcl0193775
RE25570 FBcl0215138
RE61253 FBcl0215375
RE48977 FBcl0215394
RE53076 FBcl0215428
RE54196 FBcl0215433
RE51937 FBcl0215457

15 Exons

DB identifier Symbol
FBgn0010303:15 hep:15
FBgn0010303:14 hep:14
FBgn0010303:13 hep:13
FBgn0010303:12 hep:12
FBgn0010303:11 hep:11
FBgn0010303:7 hep:7
FBgn0010303:6 hep:6
FBgn0010303:5 hep:5
FBgn0010303:4 hep:4
FBgn0010303:2 hep:2
FBgn0010303:10 hep:10
FBgn0010303:9 hep:9
FBgn0010303:3 hep:3
FBgn0010303:1 hep:1
FBgn0010303:8 hep:8

5 Transcripts

DB identifier Gene
FBtr0330396 hep
FBtr0073747 hep
FBtr0330397 hep
FBtr0340303 hep
FBtr0073748 hep

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073747-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073748-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340303-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330396-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330397-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073747-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073748-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340303-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330396-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330397-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32256 NCBI Entrez Gene identifiers FBgn0010303
58642 BioGRID FBgn0010303

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1793.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1051.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2267.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1404.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1777.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 363.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2765.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2328.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 718.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1832.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2834.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 853.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2543.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1035.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1780.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1555.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2918.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1293.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1036.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1406.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2036.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1629.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1514.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1762.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1076.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2960.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1604.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 995.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1649.0
FBgn0010303 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1327.0

15 Introns

DB identifier
Organism . Name
intron_FBgn0010303:15_FBgn0010303:14 Drosophila melanogaster
intron_FBgn0010303:14_FBgn0010303:13 Drosophila melanogaster
intron_FBgn0010303:13_FBgn0010303:12 Drosophila melanogaster
intron_FBgn0010303:12_FBgn0010303:11 Drosophila melanogaster
intron_FBgn0010303:11_FBgn0010303:7 Drosophila melanogaster
intron_FBgn0010303:7_FBgn0010303:6 Drosophila melanogaster
intron_FBgn0010303:6_FBgn0010303:5 Drosophila melanogaster
intron_FBgn0010303:5_FBgn0010303:3 Drosophila melanogaster
intron_FBgn0010303:3_FBgn0010303:1 Drosophila melanogaster
intron_FBgn0010303:5_FBgn0010303:4 Drosophila melanogaster
intron_FBgn0010303:4_FBgn0010303:2 Drosophila melanogaster
intron_FBgn0010303:11_FBgn0010303:10 Drosophila melanogaster
intron_FBgn0010303:10_FBgn0010303:9 Drosophila melanogaster
intron_FBgn0010303:10_FBgn0010303:8 Drosophila melanogaster
intron_FBgn0010303:8_FBgn0010303:6 Drosophila melanogaster

55 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage hep none -0.001917554   19067489
Lipid storage hep none 0.029045932   19067489
Lipid storage hep none -1.475653561   19067489
Lipid storage hep none 0.261439806   19067489
Lipid storage hep none 0.265338394   19067489
Lipid storage hep none -2.152927752   19067489
Neural outgrowth hep Cell cluster defect np   18604272
Cell cycle regulation (1) hep none np   15616552
Cell cycle regulation (2) hep none np   15616552
Cell size and cell-cycle regulation (1) hep none sp   16496002
Cell size and cell-cycle regulation (1) hep none sp   16496002
Cell size and cell-cycle regulation (1) hep none sp   16496002
C. trachomatis infection hep C. trachomatis infection down np   18369471
Mutant human huntingtin aggregation hep Increased mutant human huntingtin aggregation >= 2   19789644
Muscle morphogenesis and function (1) hep none np   20220848
Muscle morphogenesis and function (1) hep none np   20220848
Heat nociception (1) hep Developmentally lethal 0   21074052
Heat nociception (1) hep none 0.05   21074052
Heart development and function (1) hep none 1   20371351
Serratia marcescens infection (1) hep none -0.170454545454545   19520911
Serratia marcescens infection (1) hep none 0.506172839506172   19520911
Serratia marcescens infection (1) hep none -0.425925925925925   19520911
Serratia marcescens infection (1) hep none 0.268518518518518   19520911
Notch pathway regulation (4) hep none 0   19363474
Notch pathway regulation (4) hep none 0   19363474
Notch pathway regulation (4) hep none 0   19363474
PGN-induced dJNK phosphorylation hep Decreased P-JNK protein expression with PGN -3.04 15 min PGN induction 19893628
Adiposity regulation (1) hep none -0.284   20074523
Adiposity regulation (1) hep none 0.29   20074523
Adiposity regulation (1) hep none 0.652   20074523

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