modENCODE |  Help |  blog

Gene : His3.3A D. melanogaster

DB identifier  ? FBgn0014857 Secondary Identifier  ? CG5825
Name  ? Histone H3.3A Source  FlyBase
  • synonyms:
  • histone variant 3.3,
  • H3L-like histone,
  • His-3.3A,
  • FBgn0014857,
  • H3.3,
  • histone variant H3.3,
  • histone H3.3A,
  • FBan0005825,
  • histone H3.3,
  • dH3.3A,
  • H3.3A,
  • His3.3,
  • PH3,
  • CG5825,
  • histone H3.3 variant

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

31 Alleles

DB identifier Symbol Allele Class Organism
FBal0248470 His3.3A[KO]   Drosophila melanogaster
FBal0280301 His3.3A[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0280302 His3.3A[Scer\UAS.T:Zzzz\KO-mKO]   Drosophila melanogaster
FBal0212335 His3.3A[MtnA.BLRP]   Drosophila melanogaster
FBal0212336 His3.3A[core.MtnA.BLRP]   Drosophila melanogaster
FBal0281466 His3.3A[HMS02455]   Drosophila melanogaster
FBal0131006 His3.3A[KG02455]   Drosophila melanogaster
FBal0215671 His3.3A[Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0150795 His3.3A[Delta310.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150794 His3.3A[Delta319.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150793 His3.3A[Delta335.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150792 His3.3A[Delta342.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150791 His3.3A[A87S.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0183308 His3.3A[copia.LTR.T:Disc\RFP-mRFP]   Drosophila melanogaster
FBal0183307 His3.3A[core.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150790 His3.3A[G90M.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150787 His3.3A[hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150789 His3.3A[I89V.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0150788 His3.3A[S31A.hs.T:Avic\GFP]   Drosophila melanogaster
FBal0190630 His3.3A[T:Zzzz\FLAG]   Drosophila melanogaster
FBal0207292 His3.3A[GD4748]   Drosophila melanogaster
FBal0242706 His3.3A[2X1]   Drosophila melanogaster
FBal0242707 His3.3A[T:Zzzz\FLAG.cSa]   Drosophila melanogaster
FBal0242708 His3.3A[H3.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0242709 His3.3A[K4R.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0242710 His3.3A[K9R.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0242711 His3.3A[S31A.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0226940 His3.3A[5-HA-1043]   Drosophila melanogaster
FBal0226941 His3.3A[5-HA-3051]   Drosophila melanogaster
FBal0237640 His3.3A[KK111754]   Drosophila melanogaster

202 Clones

Secondary Identifier DB identifier
EK096159 FBcl0032900
AT01868 FBcl0041371
AT19093 FBcl0041377
bs13a05 FBcl0057435
EC35135 FBcl0072441
EC32385 FBcl0072443
EN12263 FBcl0101303
GH08293 FBcl0131875
GH16032 FBcl0131887
GM04142 FBcl0143471
GM29381 FBcl0148159
GM25926 FBcl0148160
LD11584 FBcl0161476
LD25548 FBcl0177041
LD45863 FBcl0177042
LD30804 FBcl0177043
RE21618 FBcl0232861
RE69182 FBcl0232871
RE33262 FBcl0232875
RE50589 FBcl0232877
RE45342 FBcl0232880
RE65981 FBcl0232882
RE44692 FBcl0232885
RE44664 FBcl0232887
RE13754 FBcl0232888
RE70901 FBcl0232890
RE54606 FBcl0232892
RE67395 FBcl0232895
RE64074 FBcl0232898
RE61526 FBcl0232899

4 Exons

DB identifier Symbol
FBgn0014857:1 His3.3A:1
FBgn0014857:3 His3.3A:3
FBgn0014857:2 His3.3A:2
FBgn0014857:4 His3.3A:4

3 Transcripts

DB identifier Gene
FBtr0079010 His3.3A
FBtr0333537 His3.3A
FBtr0333536 His3.3A

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079010-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333536-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333537-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079010-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333536-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333537-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33736 NCBI Entrez Gene identifiers FBgn0014857
59912 BioGRID FBgn0014857

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 5325.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 6623.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 4822.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3985.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5048.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4408.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3093.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4072.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2697.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 5031.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3740.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1328.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2759.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3048.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2376.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4870.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3626.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3724.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 4823.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2872.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4855.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4105.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 3543.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3172.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2150.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4540.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5074.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 7041.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 7623.0
FBgn0014857 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 9775.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0014857:1_FBgn0014857:3 Drosophila melanogaster
intron_FBgn0014857:2_FBgn0014857:4 Drosophila melanogaster
intron_FBgn0014857:2_FBgn0014857:3 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage His3.3A Increased lipid droplet area 2.973317967   19067489
Lipid storage His3.3A Increased lipid droplet area 2.713757165   19067489
ERK signaling His3.3A ERK activation reduced strong   17086199
Cell morphology His3.3A Morphology np   14527345
Cell size and cell-cycle regulation (1) His3.3A none sp   16496002
Cell size and cell-cycle regulation (1) His3.3A none sp   16496002
Candida albicans phagocytosis (1) His3.3A none np   16336044
Heat nociception (1) His3.3A none -1.17   21074052
Serratia marcescens infection (1) His3.3A none -0.634408602150537   19520911
Serratia marcescens infection (1) His3.3A none -0.260273972602739   19520911
Notch pathway regulation (4) His3.3A Completely lethal (pupal) sp   19363474
Notch induced transcription His3.3A none 1.2049 without Notch stimulation 20959007
Notch induced transcription His3.3A Downregulation of Notch pathway after Notch stimulation -2.6879 N(delta)ecn Notch stimulation 20959007
Notch induced transcription His3.3A Downregulation of Notch pathway after Notch stimulation -2.4871 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) His3.3A none -0.471   20074523
RTK-Ras-ERK pathway regulation (1) His3.3A Decreased ERK phosphorylation after EGF stimulation -1.7 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) His3.3A Decreased ERK phosphorylation after EGF stimulation -2.63 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) His3.3A none 0.33 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) His3.3A Increased ERK phosphorylation after sSpitz and EGF stimulation 1.78 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation His3.3A none 2.06   23263283
Glycosylation regulation (1) His3.3A Decreased Chp protein expression np   21203496

0 Submissions