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Gene : Cdc42 D. melanogaster
DB identifier  ? FBgn0010341 Secondary Identifier  ? CG12530
Name  ? Cdc42 Source  FlyBase
  • synonyms:
  • Cdc42Dm,
  • Cdc42-like,
  • FBan0012530,
  • DmCDC42,
  • FBgn0010341,
  • CDC42,
  • DCDC42,
  • D-CDC42,
  • Dm Cdc42,
  • CG12530,
  • FBgn0012059,
  • P40793
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54 Alleles

DB identifier Symbol Allele Class Organism
FBal0277316 Cdc42[Scer\UAS.T:SV5\V5]   Drosophila melanogaster
FBal0284170 Cdc42[sqh.T:Disc\RFP-mCherry]   Drosophila melanogaster
FBal0266982 Cdc42[NIG.1253OR]   Drosophila melanogaster
FBal0176315 Cdc42[dsRNA.UTR.cIa]   Drosophila melanogaster
FBal0266319 Cdc42[GL00620]   Drosophila melanogaster
FBal0283057 Cdc42[dsRNA.shRNA.Scer\UAS.P\T]   Drosophila melanogaster
FBal0283058 Cdc42[Scer\UAS.P\T.T:Avic\GFP-YFP.Venus,T:Avic\GFP-ECFP]   Drosophila melanogaster
FBal0283059 Cdc42[N17.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus,T:Avic\GFP-ECFP]   Drosophila melanogaster
FBal0283060 Cdc42[V12.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus,T:Avic\GFP-ECFP]   Drosophila melanogaster
FBal0281555 Cdc42[HMS02553]   Drosophila melanogaster
FBal0242692 Cdc42[Scer\UAS.T:Avic\GFP-CFP,T:CBD-WASp,T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0062060 Cdc42[N17.hs]   Drosophila melanogaster
FBal0062067 Cdc42[+t36]   Drosophila melanogaster
FBal0062058 Cdc42[Ubi-p63E.PF]   Drosophila melanogaster
FBal0094048 Cdc42[GMR.PN]   Drosophila melanogaster
FBal0094873 Cdc42[wt.cCa]   Drosophila melanogaster
FBal0062066 Cdc42[1]   Drosophila melanogaster
FBal0148110 Cdc42[dsRNA.cCa]   Drosophila melanogaster
FBal0156785 Cdc42[dsRNA.cKa]   Drosophila melanogaster
FBal0062062 Cdc42[5] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0062063 Cdc42[4] loss of function allele Drosophila melanogaster
FBal0176317 Cdc42[DA.MtnA]   Drosophila melanogaster
FBal0240825 Cdc42[JF02855]   Drosophila melanogaster
FBal0062061 Cdc42[6] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0104881 Cdc42[unspecified]   Drosophila melanogaster
FBal0062064 Cdc42[3] loss of function allele Drosophila melanogaster
FBal0062065 Cdc42[2] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0150933 Cdc42[dsRNA.cSa]   Drosophila melanogaster
FBal0062059 Cdc42[F89.Scer\UAS]   Drosophila melanogaster
FBal0123294 Cdc42[L89.Scer\UAS]   Drosophila melanogaster

185 Clones

Secondary Identifier DB identifier
ESG019d.E21_G05 FBcl0000106
ESG0110a.E21_G08 FBcl0003667
UUGC0833 FBcl0004675
EC40715 FBcl0065471
EP11738 FBcl0079431
EP11754 FBcl0079449
EP09344 FBcl0083027
EN12917 FBcl0094199
EN09345 FBcl0094223
EN13231 FBcl0094225
EN04131 FBcl0094239
EN00628 FBcl0094299
EN15046 FBcl0097103
EN13322 FBcl0097137
EK255417 FBcl0107296
EK149351 FBcl0108608
EK107212 FBcl0108706
EK054207 FBcl0108718
EK209258 FBcl0108848
EK196030 FBcl0109142
EK207550 FBcl0109312
EK230929 FBcl0109528
EK063303 FBcl0114452
EK027436 FBcl0114464
EK162029 FBcl0114494
EK292920 FBcl0114510
EK309301 FBcl0114548
EK184021 FBcl0114554
EK158717 FBcl0114562
EK188915 FBcl0116974

7 Exons

DB identifier Symbol
FBgn0010341:7 Cdc42:7
FBgn0010341:1 Cdc42:1
FBgn0010341:3 Cdc42:3
FBgn0010341:2 Cdc42:2
FBgn0010341:5 Cdc42:5
FBgn0010341:6 Cdc42:6
FBgn0010341:4 Cdc42:4

5 Transcripts

DB identifier Gene
FBtr0309216 Cdc42
FBtr0309215 Cdc42
FBtr0309214 Cdc42
FBtr0074751 Cdc42
FBtr0074752 Cdc42

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074751-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0309214-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0309215-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074751-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0309214-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0309215-3-prime-utr Drosophila melanogaster

Interactions

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Other

22 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
32981 NCBI Entrez Gene identifiers FBgn0010341
59277 BioGRID FBgn0010341

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 6279.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 5740.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3775.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 5165.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4837.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4756.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 8081.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 6117.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 4775.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 5464.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 6419.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2502.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 6953.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 5434.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 6038.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 5898.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 7066.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4366.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6239.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 6274.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5671.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 5751.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 4239.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3911.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 5934.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6009.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5980.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 5240.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 3339.0
FBgn0010341 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4297.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0010341:3_FBgn0010341:5 Drosophila melanogaster
intron_FBgn0010341:5_FBgn0010341:7 Drosophila melanogaster
intron_FBgn0010341:2_FBgn0010341:5 Drosophila melanogaster
intron_FBgn0010341:5_FBgn0010341:6 Drosophila melanogaster
intron_FBgn0010341:4_FBgn0010341:6 Drosophila melanogaster
intron_FBgn0010341:1_FBgn0010341:5 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cdc42 none 0.423165551   19067489
Lipid storage Cdc42 none -0.083102631   19067489
Chlamydia caviae infection Cdc42 Decreased Chlamydia caviae infection np   17967059
Cell morphology Cdc42 Morphology np   14527345
Actin morphology Cdc42 Perturbed formation of actin-based protrusions np   14588242
Actin morphology Cdc42 Formation of thin processes np   12975351
Intracellular Listeria monocytogenes infection Cdc42 Decreased GFP protein expression strong   16020693
Mycobacterial infection (1) - M. fortuitum infection Cdc42 Decreased M. fortuitum intracellular infection 8.8 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Cdc42 Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Cdc42 none sp   16496002
Cell size and cell-cycle regulation (1) Cdc42 none sp   16496002
Candida albicans phagocytosis (1) Cdc42 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Cdc42 none 46   16336044
Candida albicans phagocytosis (3) Cdc42 none 47   16336044
Brucella melitensis infection Cdc42 Decreased Brucella melitensis infection 60.78   18654626
Lipid storage Cdc42 Altered total signal automated analysis   18408709
Notch pathway regulation (1) Cdc42 Upregulation of Notch pathway np   20493818
Hippo pathway regulation Cdc42 none -1.58   23263283
Muscle development and maintenance Cdc42 none sp  
Glycosylation regulation (1) Cdc42 none sp   21203496

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