Genomics
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63 Alleles
219 Clones
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0015799:4 | Rbf:4 |
| FBgn0015799:8 | Rbf:8 |
| FBgn0015799:7 | Rbf:7 |
| FBgn0015799:3 | Rbf:3 |
| FBgn0015799:2 | Rbf:2 |
| FBgn0015799:1 | Rbf:1 |
| FBgn0015799:6 | Rbf:6 |
| FBgn0015799:5 | Rbf:5 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0070146-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070146-3-prime-utr | Drosophila melanogaster |
Other
35 Pathways
- TGFBR1 KD Mutants in Cancer,
- Loss of Function of TGFBR1 in Cancer,
- Cell Cycle, Mitotic,
- Inhibition of replication initiation of damaged DNA by RB1/E2F1,
- Signaling by TGF-beta Receptor Complex in Cancer,
- SMAD4 MH2 Domain Mutants in Cancer,
- G0 and Early G1,
- Loss of Function of TGFBR2 in Cancer,
- Mitotic G2-G2/M phases,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer,
- DNA Replication,
- Generic Transcription Pathway,
- TGF-beta receptor signaling activates SMADs,
- Signaling Pathways,
- G1/S Transition,
- G1 Phase,
- Loss of Function of SMAD2/3 in Cancer,
- Loss of Function of SMAD4 in Cancer,
- Cell Cycle,
- Gene Expression,
- E2F mediated regulation of DNA replication,
- Cyclin D associated events in G1,
- Disease,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,
- Signaling by TGF-beta Receptor Complex,
- Signaling by Activin,
- TGFBR2 Kinase Domain Mutants in Cancer,
- TGFBR1 LBD Mutants in Cancer,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- Developmental Biology,
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- Mitotic M-M/G1 phases,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- Mitotic G1-G1/S phases,
- Signaling by NODAL
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31027 | NCBI Entrez Gene identifiers | FBgn0015799 |
| 57595 | BioGRID | FBgn0015799 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Rbf | none | -1.367094876 | 19067489 | |
| E2F signaling | Rbf | E2F signaling upregulated | np | 17517653 | |
| Cell size and cell-cycle regulation (1) | Rbf | Decreased G1 cell size | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Rbf | Decreased G1 cell size | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | Rbf | none | 1.243 | 16496002 | |
| Cell size and cell-cycle regulation (2) | Rbf | none | 1.339 | 16496002 | |
| Cell size and cell-cycle regulation (3) | Rbf | none | 465 | 16496002 | |
| Cell size and cell-cycle regulation (3) | Rbf | none | 522 | 16496002 | |
| Cell size and cell-cycle regulation (4) | Rbf | Increased number of mitotic cells | 0.8 | 16496002 | |
| Cell size and cell-cycle regulation (4) | Rbf | none | below threshold | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (2) | Rbf | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | Rbf | Lethal | np | 20220848 | |
| Heat nociception (1) | Rbf | none | 0.18 | 21074052 | |
| Heart development and function (1) | Rbf | none | 1 | 20371351 | |
| Notch pathway regulation (4) | Rbf | Notum malformation death | 6 | 19363474 | |
| G2-M DNA damage checkpoint regulation (2) | Rbf | Increased histone H3 phosphorylation with doxorubicin | 29.59 | with doxorubicin | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | Rbf | Increased histone H3 phosphorylation with etoposide | 30.02 | with etoposide | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | Rbf | Increased histone H3 phosphorylation after X-ray exposure | 38.05 | X-ray exposure | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | Rbf | none | 12.16 | with bleocin | 21205937 |
| Hippo pathway regulation | Rbf | none | 1.12 | 23263283 | |
| Glycosylation regulation (1) | Rbf | none | sp | 21203496 |
