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Gene : Cdc37 D. melanogaster
DB identifier  ? FBgn0011573 Secondary Identifier  ? CG12019
Name  ? Cdc37 Source  FlyBase
  • synonyms:
  • E(sev)3B,
  • FBan0012019,
  • DROCPDR,
  • FBgn0004640,
  • CPDR-2,
  • CPDR-1,
  • cdc37 protein,
  • FBgn0011573,
  • cdc37,
  • CG12019
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Lists
This Gene is in 2 lists:
Fly classI (1496)
Fly classIb (585)

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20 Alleles

DB identifier Symbol Allele Class Organism
FBal0220927 Cdc37[G7101]   Drosophila melanogaster
FBal0243679 Cdc37[+t9.5.Deltadpatj]   Drosophila melanogaster
FBal0259195 Cdc37[KK102575]   Drosophila melanogaster
FBal0033497 Cdc37[+t9.5]   Drosophila melanogaster
FBal0033498 Cdc37[+tpW8spKA]   Drosophila melanogaster
FBal0097379 Cdc37[EHHS]   Drosophila melanogaster
FBal0097380 Cdc37[+tCOSMY8-1]   Drosophila melanogaster
FBal0097381 Cdc37[+tCOSMY1-1]   Drosophila melanogaster
FBal0029088 Cdc37[e1E]   Drosophila melanogaster
FBal0029087 Cdc37[e1C]   Drosophila melanogaster
FBal0029089 Cdc37[e4D]   Drosophila melanogaster
FBal0029090 Cdc37[e6B] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0089774 Cdc37[unspecified]   Drosophila melanogaster
FBal0145137 Cdc37[dsRNA.cLa]   Drosophila melanogaster
FBal0263311 Cdc37[HMS01401]   Drosophila melanogaster
FBal0239682 Cdc37[JF03184]   Drosophila melanogaster
FBal0206539 Cdc37[GD14633]   Drosophila melanogaster
FBal0214434 Cdc37[GD1220]   Drosophila melanogaster
FBal0271079 Cdc37[NIG.12019R]   Drosophila melanogaster
FBal0222052 Cdc37[5-SZ-3021]   Drosophila melanogaster

55 Clones

Secondary Identifier DB identifier
DPiM_FI07667 FBcl0740992
UUGC1005 FBcl0005423
AT13416 FBcl0025163
AT15196 FBcl0025225
AT13188 FBcl0025227
EK053616 FBcl0031936
EK262643 FBcl0031992
bs08e10 FBcl0052405
bs46h10 FBcl0052415
EC23686 FBcl0068035
EN04932 FBcl0096831
GH12276 FBcl0133625
GH20989 FBcl0133637
GM07061 FBcl0141825
GM01424 FBcl0141826
GM18283 FBcl0146423
LD05876 FBcl0161597
LD13064 FBcl0161768
LD15504 FBcl0161788
LD18155 FBcl0161952
LD22215 FBcl0177141
LD34866 FBcl0177148
LD22680 FBcl0177327
LD40696 FBcl0177330
LD31693 FBcl0177353
LD31184 FBcl0177355
LD34689 FBcl0177358
LD27840 FBcl0177360
LD41463 FBcl0177362
LD23749 FBcl0177376

4 Exons

DB identifier Symbol
FBgn0011573:1 Cdc37:1
FBgn0011573:2 Cdc37:2
FBgn0011573:3 Cdc37:3
FBgn0011573:4 Cdc37:4

1 Transcripts

DB identifier Gene
FBtr0072777 Cdc37

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072777-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072777-3-prime-utr Drosophila melanogaster

Interactions

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5 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
38232 NCBI Entrez Gene identifiers FBgn0011573
63764 BioGRID FBgn0011573

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1664.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1359.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1228.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2536.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3017.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1391.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1698.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2065.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1628.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2997.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1999.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1850.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1469.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1761.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3378.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1313.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1555.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2409.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1492.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1726.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3132.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2169.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1660.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1254.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1702.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2558.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1839.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1736.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1494.0
FBgn0011573 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1567.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0011573:1_FBgn0011573:2 Drosophila melanogaster
intron_FBgn0011573:2_FBgn0011573:3 Drosophila melanogaster
intron_FBgn0011573:3_FBgn0011573:4 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cdc37 none 0.73632318   19067489
Lipid storage Cdc37 none 1.01231269   19067489
Cell size and cell-cycle regulation (1) Cdc37 none sp   16496002
Muscle morphogenesis and function (1) Cdc37 Lethal np   20220848
Heat nociception (1) Cdc37 none -0.47   21074052
Heart development and function (1) Cdc37 Adult lethal 0.5   20371351
Heart development and function (1) Cdc37 Embryonic lethal or no offspring 0.5   20371351
Heart development and function (2) Cdc37 Decreased viability 7.07   20371351
Serratia marcescens infection (1) Cdc37 none -0.407407407407407   19520911
Serratia marcescens infection (1) Cdc37 none -0.188888888888888   19520911
Notch pathway regulation (4) Cdc37 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Cdc37 Completely lethal (pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Cdc37 GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Notch pathway regulation (1) Cdc37 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Cdc37 Lethal strong C96-GAL4 20493818
Notch pathway regulation (2) Cdc37 Lethal very strong en-GAL4 20493818
Notch pathway regulation (2) Cdc37 Upregulation of Notch pathway; wing pouch: spoon-like sp C96-GAL4 20493818
Notch pathway regulation (3) Cdc37 Lethal np   20493818
Adiposity regulation (1) Cdc37 none -0.743   20074523
Adiposity regulation (1) Cdc37 none -0.041   20074523
Vaccinia virus infection Cdc37 none sp   20585561
RTK-Ras-ERK pathway regulation (1) Cdc37 none 0.3 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Cdc37 none 0.14 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cdc37 none -0.27 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cdc37 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.46 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Cdc37 none -1.22   23263283
Glycosylation regulation (1) Cdc37 none sp   21203496

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