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Gene : AGO1 D. melanogaster

DB identifier  ? FBgn0262739 Secondary Identifier  ? CG6671
Name  ? Argonaute-1 Source  FlyBase
  • synonyms:
  • l(2)4845,
  • l(2)k00208,
  • ARGONAUTE-1,
  • l(2)04845,
  • FBgn0022056,
  • l(2)k08121,
  • FBgn0262739,
  • mRNA-like ncRNA in embryogenesis 20,
  • Argonaute1,
  • dAGO1,
  • FBgn0010586,
  • FBan0006671,
  • Ago,
  • Ago-1,
  • Dm Ago1,
  • Ago1,
  • Argonaute 1,
  • FBgn0086551,
  • CG6671,
  • FBgn0063793,
  • MRE20,
  • Argonaute,
  • anon-WO0257455.29,
  • FBgn0022275,
  • ago1-1,
  • FBgn0026611,
  • Argonaute protein 1,
  • DmAgo1

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70 Alleles

DB identifier Symbol Allele Class Organism
FBal0216508 AGO1[Scer\UAS.cDa]   Drosophila melanogaster
FBal0268165 AGO1[EMS]   Drosophila melanogaster
FBal0268166 AGO1[1]   Drosophila melanogaster
FBal0268167 AGO1[2]   Drosophila melanogaster
FBal0268168 AGO1[3]   Drosophila melanogaster
FBal0268169 AGO1[4]   Drosophila melanogaster
FBal0268170 AGO1[5]   Drosophila melanogaster
FBal0268171 AGO1[6]   Drosophila melanogaster
FBal0268172 AGO1[7]   Drosophila melanogaster
FBal0268173 AGO1[8]   Drosophila melanogaster
FBal0268174 AGO1[9]   Drosophila melanogaster
FBal0268175 AGO1[10]   Drosophila melanogaster
FBal0268176 AGO1[11]   Drosophila melanogaster
FBal0268177 AGO1[12]   Drosophila melanogaster
FBal0268178 AGO1[13]   Drosophila melanogaster
FBal0268179 AGO1[14]   Drosophila melanogaster
FBal0268180 AGO1[15]   Drosophila melanogaster
FBal0211604 AGO1[CA06914]   Drosophila melanogaster
FBal0281737 AGO1[Hsp83.T:Zzzz\FLAG,T:Zzzz\StrepII,T:Zzzz\His6]   Drosophila melanogaster
FBal0281738 AGO1[K657A.K694A.Hsp83.T:Zzzz\FLAG,T:Zzzz\StrepII,T:Zzzz\His6]   Drosophila melanogaster
FBal0245309 AGO1[HM04006]   Drosophila melanogaster
FBal0257295 AGO1[HMS00610]   Drosophila melanogaster
FBal0188335 AGO1[d01402]   Drosophila melanogaster
FBal0188333 AGO1[f07079]   Drosophila melanogaster
FBal0064342 AGO1[k16601]   Drosophila melanogaster
FBal0064343 AGO1[k08121] loss of function allele Drosophila melanogaster
FBal0188336 AGO1[c05033]   Drosophila melanogaster
FBal0064637 AGO1[k00208]   Drosophila melanogaster
FBal0008072 AGO1[04845]   Drosophila melanogaster
FBal0192634 AGO1[EY21521]   Drosophila melanogaster

233 Clones

Secondary Identifier DB identifier
FGH129G11 FBcl0388728
UUGC0997 FBcl0005303
ESG013d.E21_D12 FBcl0010573
EK147730 FBcl0025364
EK114726 FBcl0025374
EK061454 FBcl0012278
EK110924 FBcl0025474
EK114158 FBcl0025508
EK303005 FBcl0025516
EK217754 FBcl0025524
EK167930 FBcl0025556
EK015623 FBcl0025566
EK115428 FBcl0025574
EK139601 FBcl0025580
EK111237 FBcl0025588
EK180659 FBcl0025598
EK114505 FBcl0025606
EK222040 FBcl0025614
EK211711 FBcl0025622
EK143540 FBcl0025632
EK047937 FBcl0025642
EK272521 FBcl0025648
EK204901 FBcl0025656
EK217838 FBcl0025666
EK296364 FBcl0025674
EK194634 FBcl0025682
EK119522 FBcl0025690
EK137318 FBcl0025700
EK263556 FBcl0025710
EK239064 FBcl0025716

14 Exons

DB identifier Symbol
FBgn0262739:14 AGO1:14
FBgn0262739:13 AGO1:13
FBgn0262739:11 AGO1:11
FBgn0262739:8 AGO1:8
FBgn0262739:7 AGO1:7
FBgn0262739:6 AGO1:6
FBgn0262739:5 AGO1:5
FBgn0262739:2 AGO1:2
FBgn0262739:10 AGO1:10
FBgn0262739:9 AGO1:9
FBgn0262739:3 AGO1:3
FBgn0262739:12 AGO1:12
FBgn0262739:4 AGO1:4
FBgn0262739:1 AGO1:1

4 Transcripts

DB identifier Gene
FBtr0087612 AGO1
FBtr0305592 AGO1
FBtr0087613 AGO1
FBtr0087614 AGO1

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0087612-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087614-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087613-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0305592-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087612-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087614-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087613-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305592-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36544 NCBI Entrez Gene identifiers FBgn0262739
62298 BioGRID FBgn0262739

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

13 Introns

DB identifier
Organism . Name
intron_FBgn0262739:14_FBgn0262739:13 Drosophila melanogaster
intron_FBgn0262739:13_FBgn0262739:11 Drosophila melanogaster
intron_FBgn0262739:11_FBgn0262739:8 Drosophila melanogaster
intron_FBgn0262739:8_FBgn0262739:7 Drosophila melanogaster
intron_FBgn0262739:7_FBgn0262739:6 Drosophila melanogaster
intron_FBgn0262739:6_FBgn0262739:5 Drosophila melanogaster
intron_FBgn0262739:5_FBgn0262739:2 Drosophila melanogaster
intron_FBgn0262739:5_FBgn0262739:1 Drosophila melanogaster
intron_FBgn0262739:12_FBgn0262739:11 Drosophila melanogaster
intron_FBgn0262739:5_FBgn0262739:4 Drosophila melanogaster
intron_FBgn0262739:10_FBgn0262739:9 Drosophila melanogaster
intron_FBgn0262739:9_FBgn0262739:8 Drosophila melanogaster
intron_FBgn0262739:5_FBgn0262739:3 Drosophila melanogaster

16 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage AGO1 none 2.634946623   19067489
Lipid storage AGO1 none -3.275640515   19067489
ERK signaling AGO1 ERK activation reduced strong   17086199
Innate immunity AGO1 Decreased IMD/Rel reporter activity -5.3   16170305
Constitutive protein secretion and Golgi organization (1) AGO1 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) AGO1 none sp   16496002
Cell size and cell-cycle regulation (1) AGO1 none sp   16496002
PGN-induced dJNK phosphorylation AGO1 Increased P-JNK protein expression with PGN 2.08 15 min PGN induction 19893628
Akt-TOR pathway negative feedback regulation AGO1 Decreased dAkt phosphorylation after insulin stimulation -5.9 10 min insulin stimulation 20585550
Notch pathway regulation (1) AGO1 Upregulation of Notch pathway np   20493818
S2 cell spreading AGO1 none np   21041442
RTK-Ras-ERK pathway regulation (1) AGO1 none 1.09 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) AGO1 none 0.61 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) AGO1 none 1.17 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) AGO1 none 1.38 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation AGO1 none -1.37   23263283

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