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Gene : l(3)72Ab D. melanogaster
DB identifier  ? FBgn0263599 Secondary Identifier  ? CG5931
Name  ? lethal (3) 72Ab Source  FlyBase
  • synonyms:
  • FBan0005931,
  • FBgn0036548,
  • FBgn0263599,
  • clone 1.21,
  • ASCC3L1,
  • FBgn0004713,
  • Brr2,
  • FBgn0026003,
  • anon-EST:Liang-1.21,
  • CG5931
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20 Alleles

DB identifier Symbol Allele Class Organism
FBal0245456 l(3)72Ab[JF01149]   Drosophila melanogaster
FBal0136126 l(3)72Ab[dsRNA.cRa]   Drosophila melanogaster
FBal0185352 l(3)72Ab[f00335]   Drosophila melanogaster
FBal0204880 l(3)72Ab[GD9881]   Drosophila melanogaster
FBal0257662 l(3)72Ab[HMS00994]   Drosophila melanogaster
FBal0161217 l(3)72Ab[e03171]   Drosophila melanogaster
FBal0284495 l(3)72Ab[Z5080]   Drosophila melanogaster
FBal0284496 l(3)72Ab[Z1604]   Drosophila melanogaster
FBal0284497 l(3)72Ab[Z4474]   Drosophila melanogaster
FBal0284498 l(3)72Ab[Z2850]   Drosophila melanogaster
FBal0185353 l(3)72Ab[c05233]   Drosophila melanogaster
FBal0258789 l(3)72Ab[KK100656]   Drosophila melanogaster
FBal0185351 l(3)72Ab[f02582]   Drosophila melanogaster
FBal0009906 l(3)72Ab[2]   Drosophila melanogaster
FBal0009910 l(3)72Ab[6]   Drosophila melanogaster
FBal0009905 l(3)72Ab[1]   Drosophila melanogaster
FBal0049844 l(3)72Ab[I24]   Drosophila melanogaster
FBal0009909 l(3)72Ab[5]   Drosophila melanogaster
FBal0009908 l(3)72Ab[4]   Drosophila melanogaster
FBal0009907 l(3)72Ab[3]   Drosophila melanogaster

44 Clones

Secondary Identifier DB identifier
IP09935 FBcl0304012
AI124259 FBcl0000765
EK094251 FBcl0051692
EK160535 FBcl0051698
EK222154 FBcl0051766
EK248416 FBcl0051774
EK113302 FBcl0051778
EK138960 FBcl0051782
EK298461 FBcl0052176
EK198017 FBcl0052258
EK088753 FBcl0052288
EK116808 FBcl0052318
EK044955 FBcl0052324
EC36913 FBcl0063977
EP13146 FBcl0077883
EP01945 FBcl0077917
GH04690 FBcl0106531
GH14159 FBcl0106535
GM09620 FBcl0139435
LD04475 FBcl0152279
LD03265 FBcl0152287
LD24541 FBcl0164831
LP16036 FBcl0180707
SD26177 FBcl0279502
SD10732 FBcl0279519
EC056602 FBcl0303234
EC056187 FBcl0303235
EC055612 FBcl0303236
EC055123 FBcl0303237
EC054069 FBcl0303238

6 Exons

DB identifier Symbol
FBgn0263599:6 l(3)72Ab:6
FBgn0263599:5 l(3)72Ab:5
FBgn0263599:4 l(3)72Ab:4
FBgn0263599:3 l(3)72Ab:3
FBgn0263599:2 l(3)72Ab:2
FBgn0263599:1 l(3)72Ab:1

1 Transcripts

DB identifier Gene
FBtr0075527 l(3)72Ab

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075527-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075527-3-prime-utr Drosophila melanogaster

Interactions

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Other

7 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
39737 NCBI Entrez Gene identifiers FBgn0263599
65049 BioGRID FBgn0263599

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

5 Introns

DB identifier
Organism . Name
intron_FBgn0263599:6_FBgn0263599:5 Drosophila melanogaster
intron_FBgn0263599:5_FBgn0263599:4 Drosophila melanogaster
intron_FBgn0263599:4_FBgn0263599:3 Drosophila melanogaster
intron_FBgn0263599:3_FBgn0263599:2 Drosophila melanogaster
intron_FBgn0263599:2_FBgn0263599:1 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage l(3)72Ab none -2.479627318   19067489
Lipid storage l(3)72Ab none -0.936407478   19067489
Lipid storage l(3)72Ab none 0.212514258   19067489
ERK signaling l(3)72Ab ERK activation reduced weak   17086199
E. coli / S. aureus infection l(3)72Ab Decreased phagocytosis np   11912489
Alternative splicing l(3)72Ab Alternative Dscam (exon 4 and exon 17) splicing sp   15492211
Intracellular Listeria monocytogenes infection l(3)72Ab Decreased GFP protein expression moderate   16020693
Hedgehog signaling l(3)72Ab Decreased Hedgehog reporter activity -3.23   16311596
Constitutive protein secretion and Golgi organization (1) l(3)72Ab Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) l(3)72Ab none sp   16496002
Microtubule assembly and organization l(3)72Ab Decreased centrosome number np   18463163
Mutant human huntingtin aggregation l(3)72Ab Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) l(3)72Ab none np   20220848
Heat nociception (1) l(3)72Ab none -0.26   21074052
Regulated secretory pathway biogenesis (1) l(3)72Ab none 1   21149569
Heart development and function (1) l(3)72Ab none 1   20371351
Serratia marcescens infection (1) l(3)72Ab none 0.319148936170212   19520911
Notch pathway regulation (4) l(3)72Ab none 0   19363474
Muscle assembly and maintenance l(3)72Ab Muscles with short and/or thin myofibrils severe   18359903
Hh pathway regulation l(3)72Ab Downregulation of Hh pathway -0.371329908102896   17903264
Hh pathway regulation l(3)72Ab Downregulation of Hh pathway -0.511936448373311   17903264
Adiposity regulation (1) l(3)72Ab none -0.527   20074523
RTK-Ras-ERK pathway regulation (1) l(3)72Ab Decreased ERK phosphorylation after EGF stimulation -2.05 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) l(3)72Ab none -0.89 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(3)72Ab none -0.49 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(3)72Ab none -1.16 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation l(3)72Ab none -0.47   23263283

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