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Gene : MBD-R2 D. melanogaster

DB identifier  ? FBgn0038016 Secondary Identifier  ? CG10042
Name  ? MBD-R2 Source  FlyBase
  • synonyms:
  • dMBD-R2,
  • FBgn0038015,
  • TAM3,
  • CG10042,
  • FBgn0038016,
  • MBD,
  • CG17393,
  • Mbrd2,
  • mbd-R2,
  • FBan0010042,
  • MBDR2,
  • Dm Tam3

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0241710 MBD-R2[HM05219]   Drosophila melanogaster
FBal0220719 MBD-R2[JF02351]   Drosophila melanogaster
FBal0270301 MBD-R2[NIG.10042R]   Drosophila melanogaster
FBal0258994 MBD-R2[KK101655]   Drosophila melanogaster
FBal0147799 MBD-R2[KG09669]   Drosophila melanogaster
FBal0207540 MBD-R2[GD6844]   Drosophila melanogaster

66 Clones

Secondary Identifier DB identifier
EK197904 FBcl0021166
EK205532 FBcl0021762
EK289401 FBcl0022666
EK057935 FBcl0022988
EK299860 FBcl0023030
EK165251 FBcl0023086
EK134217 FBcl0023820
EK085023 FBcl0023870
EK068347 FBcl0023958
EK291206 FBcl0023968
EK222153 FBcl0023972
EK185918 FBcl0014592
EP05430 FBcl0090191
EP12536 FBcl0090193
LP24022 FBcl0190959
RE56663 FBcl0236218
RE58517 FBcl0236224
RE34763 FBcl0236226
RE25839 FBcl0236228
RE45650 FBcl0236230
SD03893 FBcl0292410
SD10773 FBcl0292411
SD01905 FBcl0292412
SD09271 FBcl0292413
SD02124 FBcl0292414
SD08901 FBcl0292415
RM05213 FBcl0368859
RM06113 FBcl0368860
RM06313 FBcl0368861
RM06413 FBcl0368862

5 Exons

DB identifier Symbol
FBgn0038016:5 MBD-R2:5
FBgn0038016:4 MBD-R2:4
FBgn0038016:3 MBD-R2:3
FBgn0038016:2 MBD-R2:2
FBgn0038016:1 MBD-R2:1

1 Transcripts

DB identifier Gene
FBtr0082611 MBD-R2

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0082611-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082611-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41498 NCBI Entrez Gene identifiers FBgn0038016
66608 BioGRID FBgn0038016

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2231.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2322.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1332.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2204.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2132.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1678.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2581.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2083.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2393.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1823.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1700.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1006.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1924.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1489.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2007.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1801.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1781.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1532.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1851.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1638.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1941.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1732.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2669.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2317.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2536.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2682.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1034.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1671.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1455.0
FBgn0038016 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1192.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0038016:5_FBgn0038016:4 Drosophila melanogaster
intron_FBgn0038016:4_FBgn0038016:3 Drosophila melanogaster
intron_FBgn0038016:3_FBgn0038016:2 Drosophila melanogaster
intron_FBgn0038016:2_FBgn0038016:1 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage MBD-R2 none 0.013111106   19067489
Lipid storage MBD-R2 none 1.265434178   19067489
Histone pre-mRNA processing MBD-R2 Histone pre-mRNA processing defect 3   18042462
Hedgehog signaling MBD-R2 Increased Hedgehog reporter activity 5.37   16311596
Constitutive protein secretion and Golgi organization (1) MBD-R2 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) MBD-R2 none sp   16496002
Muscle morphogenesis and function (1) MBD-R2 Lethal np   20220848
Heat nociception (1) MBD-R2 none -1.17   21074052
Heart development and function (1) MBD-R2 none 1   20371351
Serratia marcescens infection (1) MBD-R2 none -0.0714285714285714   19520911
Notch pathway regulation (4) MBD-R2 Completely lethal (pupal) sp   19363474
G2-M DNA damage checkpoint regulation (2) MBD-R2 Increased histone H3 phosphorylation with doxorubicin 23.1 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) MBD-R2 Increased histone H3 phosphorylation with etoposide 37.18 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) MBD-R2 Increased histone H3 phosphorylation after X-ray exposure 38.53 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) MBD-R2 none 11.41 with bleocin 21205937
Hh pathway regulation MBD-R2 Upregulation of Hh pathway 1.44219612320321   17903264
Hh pathway regulation MBD-R2 Upregulation of Hh pathway 1.71168959278122   17903264
Self-renewal and differentiation in neural stem cells MBD-R2 GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) MBD-R2 none -0.135   20074523
RTK-Ras-ERK pathway regulation (1) MBD-R2 none 0.13 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) MBD-R2 Decreased ERK phosphorylation after EGF stimulation -4.34 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MBD-R2 none -0.27 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MBD-R2 none -0.81 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation MBD-R2 none 0.92   23263283
Glycosylation regulation (1) MBD-R2 Increased alpha1,3-fucose Chp glycosylation, increased alpha1,6-fucose Chp glycosylation sp   21203496
Glycosylation regulation (2) MBD-R2 Effect on Chp glycosylation np   21203496

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