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Gene : brat D. melanogaster

DB identifier  ? FBgn0010300 Secondary Identifier  ? CG10719
Name  ? brain tumor Source  FlyBase
  • synonyms:
  • l(2)brat,
  • FBgn0010300,
  • brain tumour,
  • lincRNA.S1565,
  • fs(2)ltoPM43,
  • l(2)37Cf,
  • E60,
  • l(2)E60,
  • FBgn0027355,
  • CG10719,
  • FBgn0002034,
  • anon-37CDa,
  • Brain Tumor,
  • FBgn0004827,
  • FBan0010719,
  • Cf,
  • BRAT

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110 Alleles

DB identifier Symbol Allele Class Organism
FBal0276641 brat[MI02407]   Drosophila melanogaster
FBal0276849 brat[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0242943 brat[K1771]   Drosophila melanogaster
FBal0242944 brat[GMR.PB]   Drosophila melanogaster
FBal0266037 brat[UY1131]   Drosophila melanogaster
FBal0180703 brat[LA00378]   Drosophila melanogaster
FBal0180698 brat[d02758]   Drosophila melanogaster
FBal0180699 brat[c06399]   Drosophila melanogaster
FBal0180701 brat[c03328]   Drosophila melanogaster
FBal0180702 brat[c02693]   Drosophila melanogaster
FBal0159442 brat[EY13747]   Drosophila melanogaster
FBal0180695 brat[d11404]   Drosophila melanogaster
FBal0180696 brat[d08172]   Drosophila melanogaster
FBal0180697 brat[d07606]   Drosophila melanogaster
FBal0180689 brat[f07082]   Drosophila melanogaster
FBal0180690 brat[f06309]   Drosophila melanogaster
FBal0180691 brat[f04835]   Drosophila melanogaster
FBal0180692 brat[e02225]   Drosophila melanogaster
FBal0180693 brat[e02105]   Drosophila melanogaster
FBal0180694 brat[e01842]   Drosophila melanogaster
FBal0180700 brat[c05100]   Drosophila melanogaster
FBal0064940 brat[k11538]   Drosophila melanogaster
FBal0064941 brat[k11523]   Drosophila melanogaster
FBal0064942 brat[k11508]   Drosophila melanogaster
FBal0064943 brat[k06028]   Drosophila melanogaster
FBal0155548 brat[EP2483]   Drosophila melanogaster
FBal0130486 brat[EP778]   Drosophila melanogaster
FBal0257784 brat[HMS01121]   Drosophila melanogaster
FBal0121852 brat[GTD1-31.1]   Drosophila melanogaster
FBal0121853 brat[GTD1-2.2]   Drosophila melanogaster

217 Clones

Secondary Identifier DB identifier
EK180518 FBcl0033686
EK067812 FBcl0033668
EK033344 FBcl0033710
EK291939 FBcl0033728
EK134233 FBcl0033752
EK090141 FBcl0033772
EK307450 FBcl0033794
EK064926 FBcl0033810
EK259261 FBcl0033832
EK225828 FBcl0033854
EK266958 FBcl0033876
EK084335 FBcl0033894
EK265903 FBcl0033916
EK167708 FBcl0033936
EK237026 FBcl0033956
EK010957 FBcl0033976
EK050229 FBcl0033996
EK281546 FBcl0034012
EK051629 FBcl0034046
EK113820 FBcl0034068
EK293241 FBcl0034084
EK056722 FBcl0034124
EK147440 FBcl0034146
EK216640 FBcl0034164
EK115139 FBcl0034184
EK138826 FBcl0034202
EK066339 FBcl0034244
EK165926 FBcl0034264
ESG017c.B21.1_C02 FBcl0004501
EK061405 FBcl0034284

10 Exons

DB identifier Symbol
FBgn0010300:1 brat:1
FBgn0010300:2 brat:2
FBgn0010300:5 brat:5
FBgn0010300:7 brat:7
FBgn0010300:4 brat:4
FBgn0010300:8 brat:8
FBgn0010300:3 brat:3
FBgn0010300:9 brat:9
FBgn0010300:6 brat:6
FBgn0010300:10 brat:10

4 Transcripts

DB identifier Gene
FBtr0081158 brat
FBtr0336627 brat
FBtr0081159 brat
FBtr0081160 brat

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0081158-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081159-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081160-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336627-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081158-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081159-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081160-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336627-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35197 NCBI Entrez Gene identifiers FBgn0010300
61181 BioGRID FBgn0010300

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3188.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2513.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2515.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1749.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1982.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 9805.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3608.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4322.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2032.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3288.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3671.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2033.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2296.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2581.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2682.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3183.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3114.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1251.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2236.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1837.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2911.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2231.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2825.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1561.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2607.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8173.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4932.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 5774.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 4104.0
FBgn0010300 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4793.0

9 Introns

DB identifier
Organism . Name
intron_FBgn0010300:1_FBgn0010300:2 Drosophila melanogaster
intron_FBgn0010300:2_FBgn0010300:5 Drosophila melanogaster
intron_FBgn0010300:5_FBgn0010300:6 Drosophila melanogaster
intron_FBgn0010300:6_FBgn0010300:10 Drosophila melanogaster
intron_FBgn0010300:4_FBgn0010300:5 Drosophila melanogaster
intron_FBgn0010300:5_FBgn0010300:8 Drosophila melanogaster
intron_FBgn0010300:3_FBgn0010300:5 Drosophila melanogaster
intron_FBgn0010300:5_FBgn0010300:9 Drosophila melanogaster
intron_FBgn0010300:5_FBgn0010300:7 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage brat none 0.164251116   19067489
Lipid storage brat none 0.313320672   19067489
ERK signaling brat ERK activation reduced weak   17086199
Cell size and cell-cycle regulation (1) brat none sp   16496002
Cell size and cell-cycle regulation (1) brat none sp   16496002
Candida albicans phagocytosis (1) brat Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) brat none 46   16336044
Candida albicans phagocytosis (3) brat Decreased latex beads phagocytosis 37   16336044
Mutant human huntingtin aggregation brat Decreased mutant human huntingtin aggregation <= -2   19789644
Heat nociception (1) brat none -1.17   21074052
Heart development and function (1) brat none 1   20371351
Serratia marcescens infection (1) brat none 0.17391304347826   19520911
Serratia marcescens infection (1) brat none 0.546875   19520911
Notch pathway regulation (4) brat none 0   19363474
Self-renewal and differentiation in neural stem cells brat Neuroblast more large cells, neuroblast overproliferation, lethal sp   21549331
Notch pathway regulation (1) brat Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) brat none np en-GAL4 20493818
Notch pathway regulation (3) brat Upregulation of Notch pathway np   20493818
Adiposity regulation (1) brat none 0.181   20074523
RTK-Ras-ERK pathway regulation (1) brat Increased ERK phosphorylation after EGF stimulation 2.19 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) brat Decreased ERK phosphorylation after EGF stimulation -2.67 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) brat none 0.9 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) brat Increased ERK phosphorylation after sSpitz and EGF stimulation 1.68 30 minutes sSpitz stimulation 22028469
Glycosylation regulation (1) brat none sp   21203496

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