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Gene : pAbp D. melanogaster

DB identifier  ? FBgn0265297 Secondary Identifier  ? CG5119
Source  FlyBase
  • synonyms:
  • poly-A binding protein,
  • FBgn0027713,
  • FBgn0040739,
  • FBgn0065324,
  • doppio fuso,
  • FBan0005119,
  • anon-EST:Posey247,
  • l(2)SH2 1908,
  • FBgn0027714,
  • PABPC1,
  • dPABP,
  • BcDNA:LD24412,
  • CG16803,
  • FBgn0265297,
  • duo,
  • FBgn0063151,
  • FBgn0003031,
  • polyA-binding protein,
  • FBgn0261619,
  • lethal (2) SH1908,
  • poly (A)-binding protein,
  • anon-EST:Posey249,
  • Poly(A)binding protein,
  • l(2)SH1908,
  • polyadenylate-binding protein,
  • anon-fast-evolving-2E5,
  • FBgn0025217,
  • Poly(A) binding protein,
  • l(2)k10109,
  • FBgn0021963,
  • Poly(A)-binding protein,
  • pAB,
  • CG5119,
  • unnamed,
  • anon-EST:fe2E5,
  • PABP,
  • PABP55B

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21 Alleles

DB identifier Symbol Allele Class Organism
FBal0195527 pAbp[H74.3]   Drosophila melanogaster
FBal0143561 pAbp[SH1908]   Drosophila melanogaster
FBal0263837 pAbp[37-2]   Drosophila melanogaster
FBal0263838 pAbp[Scer\UAS.P\T.T:Hsap\MYC]   Drosophila melanogaster
FBal0263839 pAbp[+t7.8]   Drosophila melanogaster
FBal0248837 pAbp[PTT-GA]   Drosophila melanogaster
FBal0178523 pAbp[d07048]   Drosophila melanogaster
FBal0158843 pAbp[EY11561]   Drosophila melanogaster
FBal0064223 pAbp[k10109]   Drosophila melanogaster
FBal0117409 pAbp[EP310]   Drosophila melanogaster
FBal0099847 pAbp[duo]   Drosophila melanogaster
FBal0248555 pAbp[B.Scer\UAS]   Drosophila melanogaster
FBal0135652 pAbp[dsRNA.cRa]   Drosophila melanogaster
FBal0261731 pAbp[CPTI002652]   Drosophila melanogaster
FBal0117408 pAbp[Scer\UAS.cSa]   Drosophila melanogaster
FBal0191977 pAbp[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0263445 pAbp[HMS01542]   Drosophila melanogaster
FBal0287445 pAbp[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0239604 pAbp[JF03104]   Drosophila melanogaster
FBal0210286 pAbp[GD11542]   Drosophila melanogaster
FBal0222093 pAbp[5-SZ-4029]   Drosophila melanogaster

944 Clones

Secondary Identifier DB identifier
AA433260 FBcl0346058
ESG0112a.B21.1_D12 FBcl0000112
EK291012 FBcl0036132
AF171851 FBcl0000299
AF171852 FBcl0000307
EK058257 FBcl0036198
ESG0112c.B21.1_G06 FBcl0001685
EK057961 FBcl0036220
ESG0116d.B21_E01 FBcl0002353
AT11786 FBcl0021951
AT15544 FBcl0021953
AT30916 FBcl0021963
AT24433 FBcl0022105
ESG015d.B21_H05 FBcl0006109
AT24156 FBcl0022249
AT27525 FBcl0022349
AT03976 FBcl0022515
AT09874 FBcl0022367
AT09548 FBcl0022369
AT01481 FBcl0022375
AT31575 FBcl0022381
AT07528 FBcl0022389
AT02441 FBcl0022403
AT07403 FBcl0022405
AT17991 FBcl0022417
AT12241 FBcl0022421
AT28365 FBcl0022425
AT25967 FBcl0022431
AT14986 FBcl0022433
AT09848 FBcl0022435

9 Exons

DB identifier Symbol
FBgn0265297:2 pAbp:2
FBgn0265297:4 pAbp:4
FBgn0265297:5 pAbp:5
FBgn0265297:6 pAbp:6
FBgn0265297:7 pAbp:7
FBgn0265297:3 pAbp:3
FBgn0265297:9 pAbp:9
FBgn0265297:1 pAbp:1
FBgn0265297:8 pAbp:8

3 Transcripts

DB identifier Gene
FBtr0086738 pAbp
FBtr0086740 pAbp
FBtr0086736 pAbp

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086736-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086740-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086738-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086736-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086740-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086738-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37070 NCBI Entrez Gene identifiers FBgn0265297
37070, 41181 NCBI Entrez Gene identifiers FBgn0265297
62753 BioGRID FBgn0265297

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

8 Introns

DB identifier
Organism . Name
intron_FBgn0265297:2_FBgn0265297:4 Drosophila melanogaster
intron_FBgn0265297:4_FBgn0265297:5 Drosophila melanogaster
intron_FBgn0265297:5_FBgn0265297:6 Drosophila melanogaster
intron_FBgn0265297:6_FBgn0265297:7 Drosophila melanogaster
intron_FBgn0265297:3_FBgn0265297:4 Drosophila melanogaster
intron_FBgn0265297:6_FBgn0265297:9 Drosophila melanogaster
intron_FBgn0265297:1_FBgn0265297:4 Drosophila melanogaster
intron_FBgn0265297:6_FBgn0265297:8 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage pAbp Increased lipid droplet area 2.304475718   19067489
Lipid storage pAbp Increased lipid droplet area 6.605815858   19067489
Neural outgrowth pAbp Excess branching np   18604272
ERK signaling pAbp ERK activation reduced strong   17086199
E. coli / S. aureus infection pAbp Cell death np   11912489
Cytokinesis regulation pAbp Binucleate cells weak   15547975
Cell size and cell-cycle regulation (1) pAbp Decreased viability sp   16496002
Cell size and cell-cycle regulation (2) pAbp none 1.37   16496002
Cell size and cell-cycle regulation (3) pAbp none 430   16496002
Candida albicans phagocytosis (1) pAbp none np   16336044
Lipid storage pAbp Smaller sized lipid droplets, more dispersed strong   18408709
Microtubule assembly and organization pAbp none np   18463163
Combinatorial effect with methyl methanesulphonate (2) pAbp Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation pAbp Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) pAbp Lethal np   20220848
Muscle morphogenesis and function (3) pAbp Fading Z-line np   20220848
Heat nociception (1) pAbp Developmentally lethal 0   21074052
Heart development and function (1) pAbp none 0.83   20371351
Heart development and function (2) pAbp Decreased viability 3.29   20371351
Serratia marcescens infection (1) pAbp none 1.32653061224489   19520911
Notch pathway regulation (4) pAbp Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation pAbp Increased P-JNK protein expression with PGN 2.71 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation pAbp Increased P-JNK protein expression with PGN 4.48 60 min PGN induction 19893628
Self-renewal and differentiation in neural stem cells pAbp GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) pAbp none -0.64   20074523
RTK-Ras-ERK pathway regulation (1) pAbp Decreased ERK phosphorylation after EGF stimulation -2.27 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) pAbp Decreased ERK phosphorylation after EGF stimulation -3.39 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) pAbp Increased ERK phosphorylation after sSpitz and EGF stimulation 2.47 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) pAbp Increased ERK phosphorylation after sSpitz and EGF stimulation 3.14 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation pAbp none -1.35   23263283

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