Genomics
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5 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0284509 | RpS11[Scer\UAS.T:Avic\GFP] | Drosophila melanogaster | |
| FBal0286919 | RpS11[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286920 | RpS11[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208369 | RpS11[GD13530] | Drosophila melanogaster | |
| FBal0222116 | RpS11[NP0211] | Drosophila melanogaster |
448 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0033699:7 | RpS11:7 |
| FBgn0033699:6 | RpS11:6 |
| FBgn0033699:4 | RpS11:4 |
| FBgn0033699:3 | RpS11:3 |
| FBgn0033699:5 | RpS11:5 |
| FBgn0033699:2 | RpS11:2 |
| FBgn0033699:1 | RpS11:1 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088006-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088007-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088006-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088007-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- Metabolism of RNA,
- Cleavage of Growing Transcript in the Termination Region,
- 3' -UTR-mediated translational regulation,
- Transport of the SLBP independent Mature mRNA,
- RNA Polymerase II Transcription,
- Processing of Capped Intron-Containing Pre-mRNA,
- RNA Polymerase II Transcription Elongation,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Formation of RNA Pol II elongation complex,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Metabolism of mRNA,
- Nonsense-Mediated Decay,
- mRNA Processing,
- Translation,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Transcription Initiation,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Translation initiation complex formation,
- RNA Polymerase II Promoter Escape,
- RNA Polymerase II Pre-transcription Events,
- Recycling of eIF2:GDP,
- Formation of the Early Elongation Complex,
- SLBP independent Processing of Histone Pre-mRNAs,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- RNA Polymerase II Transcription Termination,
- Transport of the SLBP Dependant Mature mRNA,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Metabolism of proteins,
- Elongation arrest and recovery,
- Transcription,
- Ribosomal scanning and start codon recognition,
- Eukaryotic Translation Termination,
- Processing of Intronless Pre-mRNAs,
- Transport of Mature Transcript to Cytoplasm,
- Processing of Capped Intronless Pre-mRNA,
- Gene Expression,
- Eukaryotic Translation Initiation,
- Post-Elongation Processing of the Transcript,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Peptide chain elongation,
- Formation of a pool of free 40S subunits,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Cap-dependent Translation Initiation,
- SRP-dependent cotranslational protein targeting to membrane,
- Eukaryotic Translation Elongation,
- mRNA Capping,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36321 | NCBI Entrez Gene identifiers | FBgn0033699 |
| 62099 | BioGRID | FBgn0033699 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
31 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS11 | Increased lipid droplet area | 6.345717459 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 4.708005701 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | -1.55122584 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | -1.462106281 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 2.495084512 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 2.991423824 | 19067489 | |
| ERK signaling | RpS11 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpS11 | Drosophila C virus replication down | np | 17040126 | |
| Intracellular Listeria monocytogenes infection | RpS11 | Increased GFP protein expression | strong | 16020693 | |
| Drosophila C virus infection | RpS11 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS11 | Decreased Hedgehog reporter activity | -3.89 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS11 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Influenza replication | RpS11 | Decreased Influenza replication | -1.84/-3.74 | 18615016 | |
| Lipid storage | RpS11 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS11 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS11 | none | np | 20220848 | |
| Heat nociception (1) | RpS11 | none | -1.17 | 21074052 | |
| Heart development and function (1) | RpS11 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | RpS11 | Decreased viability after Serratia marcescens infection | -1.52459016393442 | 19520911 | |
| Serratia marcescens infection (2) | RpS11 | none | sp | 19520911 | |
| Serratia marcescens infection (4) | RpS11 | none | sp | 19520911 | |
| Notch pathway regulation (4) | RpS11 | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS11 | none | 0 | 19363474 | |
| Hh pathway regulation | RpS11 | none | -0.184958912785443 | 17903264 | |
| Self-renewal and differentiation in neural stem cells | RpS11 | GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underprolif | sp | 21549331 | |
| Adiposity regulation (1) | RpS11 | none | -0.45 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS11 | Increased ERK phosphorylation after EGF stimulation | 3.09 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS11 | none | -0.8 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS11 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.96 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS11 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.45 | 30 minutes sSpitz stimulation | 22028469 |
