Genomics
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5 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0284509 | RpS11[Scer\UAS.T:Avic\GFP] | Drosophila melanogaster | |
| FBal0286919 | RpS11[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286920 | RpS11[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208369 | RpS11[GD13530] | Drosophila melanogaster | |
| FBal0222116 | RpS11[NP0211] | Drosophila melanogaster |
448 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0033699:7 | RpS11:7 |
| FBgn0033699:6 | RpS11:6 |
| FBgn0033699:4 | RpS11:4 |
| FBgn0033699:3 | RpS11:3 |
| FBgn0033699:5 | RpS11:5 |
| FBgn0033699:2 | RpS11:2 |
| FBgn0033699:1 | RpS11:1 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088006-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088007-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088006-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088007-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- mRNA Processing,
- Formation of a pool of free 40S subunits,
- Post-Elongation Processing of the Transcript,
- Processing of Capped Intron-Containing Pre-mRNA,
- Metabolism of mRNA,
- RNA Polymerase II Transcription,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Eukaryotic Translation Initiation,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Processing of Capped Intronless Pre-mRNA,
- SLBP independent Processing of Histone Pre-mRNAs,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Transcription Elongation,
- Eukaryotic Translation Termination,
- Nonsense-Mediated Decay,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Transcription,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Translation,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Cap-dependent Translation Initiation,
- mRNA Capping,
- Ribosomal scanning and start codon recognition,
- Transport of Mature Transcript to Cytoplasm,
- Transport of the SLBP independent Mature mRNA,
- Cleavage of Growing Transcript in the Termination Region,
- Metabolism of proteins,
- Gene Expression,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Peptide chain elongation,
- SRP-dependent cotranslational protein targeting to membrane,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Translation initiation complex formation,
- RNA Polymerase II Transcription Initiation,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Eukaryotic Translation Elongation,
- Processing of Intronless Pre-mRNAs,
- RNA Polymerase II Transcription Termination,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Formation of the Early Elongation Complex,
- RNA Polymerase II Pre-transcription Events,
- Recycling of eIF2:GDP,
- Transport of the SLBP Dependant Mature mRNA,
- 3' -UTR-mediated translational regulation,
- Formation of RNA Pol II elongation complex,
- Elongation arrest and recovery,
- Metabolism of RNA,
- RNA Polymerase II Promoter Escape,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- L13a-mediated translational silencing of Ceruloplasmin expression
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36321 | NCBI Entrez Gene identifiers | FBgn0033699 |
| 62099 | BioGRID | FBgn0033699 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
31 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS11 | Increased lipid droplet area | 6.345717459 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 4.708005701 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | -1.55122584 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | -1.462106281 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 2.495084512 | 19067489 | |
| Lipid storage | RpS11 | Increased lipid droplet area | 2.991423824 | 19067489 | |
| ERK signaling | RpS11 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpS11 | Drosophila C virus replication down | np | 17040126 | |
| Intracellular Listeria monocytogenes infection | RpS11 | Increased GFP protein expression | strong | 16020693 | |
| Drosophila C virus infection | RpS11 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS11 | Decreased Hedgehog reporter activity | -3.89 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS11 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Influenza replication | RpS11 | Decreased Influenza replication | -1.84/-3.74 | 18615016 | |
| Lipid storage | RpS11 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS11 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS11 | none | np | 20220848 | |
| Heat nociception (1) | RpS11 | none | -1.17 | 21074052 | |
| Heart development and function (1) | RpS11 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | RpS11 | Decreased viability after Serratia marcescens infection | -1.52459016393442 | 19520911 | |
| Serratia marcescens infection (2) | RpS11 | none | sp | 19520911 | |
| Serratia marcescens infection (4) | RpS11 | none | sp | 19520911 | |
| Notch pathway regulation (4) | RpS11 | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS11 | none | 0 | 19363474 | |
| Hh pathway regulation | RpS11 | none | -0.184958912785443 | 17903264 | |
| Self-renewal and differentiation in neural stem cells | RpS11 | GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underprolif | sp | 21549331 | |
| Adiposity regulation (1) | RpS11 | none | -0.45 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS11 | Increased ERK phosphorylation after EGF stimulation | 3.09 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS11 | none | -0.8 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS11 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.96 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS11 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.45 | 30 minutes sSpitz stimulation | 22028469 |
