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Gene : CkIalpha D. melanogaster

DB identifier  ? FBgn0015024 Secondary Identifier  ? CG2028
Name  ? Casein kinase Ialpha Source  FlyBase
  • synonyms:
  • dmckI,
  • FBgn0029043,
  • l(1)G0492,
  • CG2028,
  • CKIalpha,
  • PKA-C,
  • casein kinase-1,
  • Casein Kinase 1,
  • CK1,
  • anon-WO03040301.93,
  • Casein kinase I,
  • FBgn0066808,
  • casein kinase Ialpha,
  • caesin kinase I alpha,
  • FBgn0015024,
  • casein kinase 1a,
  • FBgn0066807,
  • Casein Kinase 1alpha,
  • CKI alpha,
  • CKI,
  • FBan0002028,
  • CK1a,
  • anon-WO03040301.95,
  • CK1alpha,
  • dmCK1,
  • CKIa,
  • CK I

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31 Alleles

DB identifier Symbol Allele Class Organism
FBal0267315 CkIalpha[8B12] amorphic allele - genetic evidence Drosophila melanogaster
FBal0239850 CkIalpha[BG01498]   Drosophila melanogaster
FBal0198083 CkIalpha[dsRNA.CRS2.Scer\UAS]   Drosophila melanogaster
FBal0184337 CkIalpha[d01603]   Drosophila melanogaster
FBal0240620 CkIalpha[Scer\UAS.T:Avic\GFP-CFP]   Drosophila melanogaster
FBal0131297 CkIalpha[EP1555]   Drosophila melanogaster
FBal0259531 CkIalpha[KK107574]   Drosophila melanogaster
FBal0102621 CkIalpha[G0492]   Drosophila melanogaster
FBal0184338 CkIalpha[K49R.Act5C.PL]   Drosophila melanogaster
FBal0148105 CkIalpha[dsRNA.320]   Drosophila melanogaster
FBal0136101 CkIalpha[dsRNA.cLa]   Drosophila melanogaster
FBal0148102 CkIalpha[dsRNA.744]   Drosophila melanogaster
FBal0148104 CkIalpha[dsRNA.400]   Drosophila melanogaster
FBal0148103 CkIalpha[dsRNA.440]   Drosophila melanogaster
FBal0148106 CkIalpha[Act5C.PL]   Drosophila melanogaster
FBal0184335 CkIalpha[dsRNA.cIa]   Drosophila melanogaster
FBal0145132 CkIalpha[dsRNA.cYa]   Drosophila melanogaster
FBal0262512 CkIalpha[GL00021]   Drosophila melanogaster
FBal0197557 CkIalpha[dsRNA.CRL.Scer\UAS]   Drosophila melanogaster
FBal0197558 CkIalpha[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0184336 CkIalpha[dsRNA.Scer\UAS.cAa]   Drosophila melanogaster
FBal0176309 CkIalpha[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0145134 CkIalpha[KN.MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0145133 CkIalpha[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0194128 CkIalpha[dsRNA.WIZ.Scer\UAS]   Drosophila melanogaster
FBal0287036 CkIalpha[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287037 CkIalpha[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0206582 CkIalpha[GD4256]   Drosophila melanogaster
FBal0279278 CkIalpha[HMS02276]   Drosophila melanogaster
FBal0219813 CkIalpha[JF01792]   Drosophila melanogaster

275 Clones

Secondary Identifier DB identifier
DPiM_LD05574 FBcl0741091
bs17h02 FBcl0047291
EP13522 FBcl0074511
EP00148 FBcl0075493
EP08741 FBcl0075707
EP01038 FBcl0076083
EP11733 FBcl0076301
EP11352 FBcl0081507
EP13420 FBcl0081921
EP21913 FBcl0082037
EP15805 FBcl0082153
EP12133 FBcl0082231
EP04034 FBcl0082281
EP07433 FBcl0082325
EN05623 FBcl0091423
EN08105 FBcl0091803
EN07629 FBcl0091925
EN03608 FBcl0092055
GH03961 FBcl0118315
GH05493 FBcl0118505
EK165050 FBcl0126198
EK141457 FBcl0126242
EK179817 FBcl0126258
EK097829 FBcl0126284
EK160337 FBcl0126294
EK071808 FBcl0126298
EK290614 FBcl0126306
EK207950 FBcl0126310
EK210659 FBcl0126314
EK188235 FBcl0126322

7 Exons

DB identifier Symbol
FBgn0015024:3 CkIalpha:3
FBgn0015024:2 CkIalpha:2
FBgn0015024:4 CkIalpha:4
FBgn0015024:5 CkIalpha:5
FBgn0015024:7 CkIalpha:7
FBgn0015024:6 CkIalpha:6
FBgn0015024:1 CkIalpha:1

4 Transcripts

DB identifier Gene
FBtr0073682 CkIalpha
FBtr0073680 CkIalpha
FBtr0300380 CkIalpha
FBtr0340408 CkIalpha

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073680-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073682-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340408-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300380-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073680-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073682-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340408-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300380-3-prime-utr Drosophila melanogaster

Interactions

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Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32221 NCBI Entrez Gene identifiers FBgn0015024
58615 BioGRID FBgn0015024

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2655.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2783.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2087.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1626.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 933.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2725.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2155.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1566.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2823.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2259.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1545.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2320.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2748.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 890.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2133.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1626.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2971.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2452.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2676.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3604.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2187.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3006.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2609.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3225.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2626.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6109.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5599.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 5925.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 4371.0
FBgn0015024 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4415.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0015024:2_FBgn0015024:4 Drosophila melanogaster
intron_FBgn0015024:4_FBgn0015024:5 Drosophila melanogaster
intron_FBgn0015024:5_FBgn0015024:7 Drosophila melanogaster
intron_FBgn0015024:3_FBgn0015024:4 Drosophila melanogaster
intron_FBgn0015024:5_FBgn0015024:6 Drosophila melanogaster
intron_FBgn0015024:1_FBgn0015024:4 Drosophila melanogaster

54 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation CkIalpha none -3.08   19216764
Lipid storage CkIalpha Increased lipid droplet area 2.05159875   19067489
Lipid storage CkIalpha Increased lipid droplet area -0.013043232   19067489
Lipid storage CkIalpha Increased lipid droplet area 2.83767202   19067489
Lipid storage CkIalpha none 2.234597113   19067489
Lipid storage CkIalpha none 0.979218928   19067489
Lipid storage CkIalpha none 1.970722569   19067489
Hedgehog signaling CkIalpha Increased Hedgehog reporter activity np   12663920
Cell cycle regulation (1) CkIalpha Increased G1 DNA content, decreased cell size sp   15616552
Cell cycle regulation (2) CkIalpha Increased G1 DNA content, decreased cell size np   15616552
Intracellular Listeria monocytogenes infection CkIalpha Decreased GFP protein expression moderate   16020693
Wnt signaling CkIalpha Increased Wnt reporter activity 11.4   15817814
Cell size and cell-cycle regulation (1) CkIalpha Increased G1 DNA content, decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) CkIalpha none sp   16496002
Cell size and cell-cycle regulation (1) CkIalpha none sp   16496002
Cell size and cell-cycle regulation (1) CkIalpha Increased G1 DNA content, decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) CkIalpha none sp   16496002
Cell size and cell-cycle regulation (2) CkIalpha none 1.194   16496002
Cell size and cell-cycle regulation (3) CkIalpha none 477   16496002
Candida albicans phagocytosis (1) CkIalpha Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) CkIalpha Decreased Escherichia coli phagocytosis 28   16336044
Candida albicans phagocytosis (3) CkIalpha Decreased latex beads phagocytosis 22   16336044
Embryonic nervous system development CkIalpha Disruption of commissures and longitudinal connectives in ventral nerve cord; hypoplasia of neurons in peripheral nervous system np   15534205
C. trachomatis infection CkIalpha C. trachomatis infection down np   18369471
Muscle morphogenesis and function (1) CkIalpha Lethal np   20220848
Muscle morphogenesis and function (1) CkIalpha Lethal np   20220848
Heat nociception (1) CkIalpha Developmentally lethal 0   21074052
Heart development and function (1) CkIalpha none 1   20371351
Serratia marcescens infection (1) CkIalpha none -0.569620253164556   19520911
Notch pathway regulation (4) CkIalpha Completely lethal (pupal) sp   19363474

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