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Gene : csw D. melanogaster

DB identifier  ? FBgn0000382 Secondary Identifier  ? CG3954
Name  ? corkscrew Source  FlyBase
  • synonyms:
  • l(1)csw,
  • 19-106,
  • l(1)2Db,
  • anon-WO03040301.207,
  • csw/SHP-2,
  • FBan0003954,
  • FBgn0026663,
  • Csw/Shp2,
  • l(1)G0170,
  • Shp2/csw,
  • anon-WO03040301.209,
  • FBgn0066826,
  • l(1)GA114,
  • FBgn0066827,
  • CG3954,
  • anon-WO03040301.219,
  • SHP-2,
  • FBgn0029599,
  • Enhancer of sevenless 1A,
  • l(1)2Dd,
  • FBgn0004637,
  • FBgn0066824,
  • EG:BACN25G24.2,
  • E(sev)1A,
  • CSW,
  • FBgn0000382,
  • Corkscrew

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63 Alleles

DB identifier Symbol Allele Class Organism
FBal0267312 csw[8C7]   Drosophila melanogaster
FBal0257060 csw[HMS00012]   Drosophila melanogaster
FBal0277173 csw[MI05169]   Drosophila melanogaster
FBal0245369 csw[HM04072]   Drosophila melanogaster
FBal0180299 csw[f06509]   Drosophila melanogaster
FBal0180300 csw[f02923]   Drosophila melanogaster
FBal0180301 csw[e04558]   Drosophila melanogaster
FBal0096809 csw[G0170]   Drosophila melanogaster
FBal0125087 csw[G0171]   Drosophila melanogaster
FBal0034376 csw[Esev1A-3EC.sev]   Drosophila melanogaster
FBal0034377 csw[Esev1A-eOP.sev]   Drosophila melanogaster
FBal0030972 csw[hs.PP]   Drosophila melanogaster
FBal0049401 csw[G547E.hs.2sev] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0049403 csw[hs.2sev]   Drosophila melanogaster
FBal0051685 csw[CS.hs.2sev] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0090452 csw[SH2SH2.hs.2sev]   Drosophila melanogaster
FBal0090454 csw[R32K.hs.2sev]   Drosophila melanogaster
FBal0090456 csw[R32K.R137K.hs.2sev]   Drosophila melanogaster
FBal0090458 csw[R137K.hs.2sev]   Drosophila melanogaster
FBal0090461 csw[Deltatail.hs.2sev]   Drosophila melanogaster
FBal0090462 csw[Deltain.hs.2sev]   Drosophila melanogaster
FBal0155427 csw[dsRNA.cMa]   Drosophila melanogaster
FBal0120524 csw[+mLa]   Drosophila melanogaster
FBal0001922 csw[3]   Drosophila melanogaster
FBal0029640 csw[Esev1A-eOP] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0001925 csw[6] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0090457 csw[R32K.R137K.Act5C]   Drosophila melanogaster
FBal0001920 csw[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0001932 csw[13]   Drosophila melanogaster
FBal0001929 csw[10]   Drosophila melanogaster

128 Clones

Secondary Identifier DB identifier
IP15884 FBcl0000140
CK00461 FBcl0058965
EC14887 FBcl0061297
EK040258 FBcl0064364
EK118632 FBcl0064374
EK201237 FBcl0064392
EK228817 FBcl0067256
EK192757 FBcl0067536
EK105928 FBcl0067740
EK292306 FBcl0067834
EK189563 FBcl0067896
EK256650 FBcl0067998
EK052120 FBcl0068030
EK046739 FBcl0068040
EK122304 FBcl0068050
EK191322 FBcl0068080
EK167820 FBcl0068090
EK124225 FBcl0068110
EK161147 FBcl0068124
EK062338 FBcl0068132
EK195540 FBcl0068144
EK056636 FBcl0068164
EK259102 FBcl0068172
EK294308 FBcl0068184
EK019812 FBcl0068212
EK057041 FBcl0068222
EK292849 FBcl0068230
EK053325 FBcl0068240
EK121116 FBcl0068248
EK193305 FBcl0068320

16 Exons

DB identifier Symbol
FBgn0000382:2 csw:2
FBgn0000382:16 csw:16
FBgn0000382:5 csw:5
FBgn0000382:3 csw:3
FBgn0000382:14 csw:14
FBgn0000382:6 csw:6
FBgn0000382:1 csw:1
FBgn0000382:4 csw:4
FBgn0000382:7 csw:7
FBgn0000382:8 csw:8
FBgn0000382:9 csw:9
FBgn0000382:10 csw:10
FBgn0000382:11 csw:11
FBgn0000382:12 csw:12
FBgn0000382:13 csw:13
FBgn0000382:15 csw:15

4 Transcripts

DB identifier Gene
FBtr0070380 csw
FBtr0333260 csw
FBtr0070379 csw
FBtr0070378 csw

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070378-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070379-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070380-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333260-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070378-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070379-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070380-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333260-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
45278 NCBI Entrez Gene identifiers FBgn0000382
69557 BioGRID FBgn0000382

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1106.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 966.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1122.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1122.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1102.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 957.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1246.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1011.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1466.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 766.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1944.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1118.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1857.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2735.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1772.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 994.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1470.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 783.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1721.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1764.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3051.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 941.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 936.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1149.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1107.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3868.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2397.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1542.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 718.0
FBgn0000382 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1134.0

15 Introns

DB identifier
Organism . Name
intron_FBgn0000382:6_FBgn0000382:7 Drosophila melanogaster
intron_FBgn0000382:7_FBgn0000382:8 Drosophila melanogaster
intron_FBgn0000382:8_FBgn0000382:9 Drosophila melanogaster
intron_FBgn0000382:9_FBgn0000382:10 Drosophila melanogaster
intron_FBgn0000382:10_FBgn0000382:11 Drosophila melanogaster
intron_FBgn0000382:11_FBgn0000382:12 Drosophila melanogaster
intron_FBgn0000382:12_FBgn0000382:13 Drosophila melanogaster
intron_FBgn0000382:13_FBgn0000382:15 Drosophila melanogaster
intron_FBgn0000382:2_FBgn0000382:3 Drosophila melanogaster
intron_FBgn0000382:3_FBgn0000382:4 Drosophila melanogaster
intron_FBgn0000382:4_FBgn0000382:7 Drosophila melanogaster
intron_FBgn0000382:13_FBgn0000382:16 Drosophila melanogaster
intron_FBgn0000382:5_FBgn0000382:7 Drosophila melanogaster
intron_FBgn0000382:12_FBgn0000382:14 Drosophila melanogaster
intron_FBgn0000382:1_FBgn0000382:3 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation csw Decreased cell size -2.22   19216764
Lipid storage csw none 2.467125579   19067489
Lipid storage csw none 1.61478766   19067489
Lipid storage csw none -1.964970849   19067489
Lipid storage csw none -1.668310318   19067489
ERK signaling csw ERK activation reduced strong   17086199
Cell size and cell-cycle regulation (1) csw none sp   16496002
Cell size and cell-cycle regulation (1) csw none sp   16496002
Muscle morphogenesis and function (1) csw none np   20220848
Heat nociception (1) csw none -0.89   21074052
Heat nociception (1) csw none 1.05   21074052
Heart development and function (1) csw none 1   20371351
Heart development and function (1) csw none 1   20371351
Serratia marcescens infection (1) csw none -0.159420289855072   19520911
Notch pathway regulation (4) csw Bristle morphology defects, planar polarity defects sp   19363474
Notch pathway regulation (4) csw Planar polarity defects, notum malformation migration sp   19363474
Notch induced transcription csw none 1.6657 without Notch stimulation 20959007
Notch induced transcription csw Upregulation of Notch pathway after Notch stimulation 3.3967 N(delta)ecn Notch stimulation 20959007
Notch induced transcription csw none 0.03787 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) csw none 0.064   20074523
Blood cell homeostasis regulation (1) csw none np   20540764
Blood cell homeostasis regulation (2) csw none np   20540764
Vaccinia virus infection csw none sp   20585561
RTK-Ras-ERK pathway regulation (1) csw none -0.06 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) csw none -0.11 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) csw Decreased ERK phosphorylation after sSpitz and EGF stimulation -3.75 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) csw Decreased ERK phosphorylation after sSpitz and EGF stimulation -3.56 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation csw none 0.45   23263283
Immune deficiency pathway regulation csw Upregulation of IMD pathway after E.coli stimulation 2.96   21297578
Glycosylation regulation (1) csw none sp   21203496

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