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Gene : Egfr D. melanogaster

DB identifier  ? FBgn0003731 Secondary Identifier  ? CG10079
Name  ? Epidermal growth factor receptor Source  FlyBase
  • synonyms:
  • EGF-receptor,
  • El,
  • CG10079,
  • unnamed,
  • morphological defects 1,
  • top/DER,
  • Ellipse torpedo,
  • DEGFR,
  • Torpedo/DER,
  • FBgn0010599,
  • l(2)57EFa,
  • faint little ball,
  • EGF Receptor,
  • l(2)05351,
  • D-Egf,
  • DER/faint little ball,
  • FBan0010079,
  • Elp-B1RB1,
  • mor1,
  • DER,
  • top/flb,
  • DER/EGFR,
  • Elp-1,
  • FBgn0003731,
  • dEGFR1,
  • C-erb,
  • FBgn0022793,
  • Ellipse,
  • d-egf-r,
  • EGF-R,
  • Torpedo/Egfr,
  • Elp-B1,
  • DmHD-33,
  • EK2-6,
  • l(2)57DEFa,
  • HD-33,
  • Torpedo,
  • flb,
  • Egf,
  • DER1,
  • DER-Ellipse,
  • DER/torpedo,
  • Drosophila epidermal growth factor receptor homologue,
  • Elp,
  • DER flb,
  • l(2)09261,
  • Epidermal Growth Factor Receptor,
  • EGFR,
  • DER/top,
  • l(2)57Ea,
  • TOP,
  • c-erbB,
  • EFG-R,
  • D-EGFR

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170 Alleles

DB identifier Symbol Allele Class Organism
FBal0268314 Egfr[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0268315 Egfr[Scer\FRT.dsRNA.slbo]   Drosophila melanogaster
FBal0268316 Egfr[dsRNA.slbo]   Drosophila melanogaster
FBal0246628 Egfr[U.A887T.Scer\UAS]   Drosophila melanogaster
FBal0248505 Egfr[T1]   Drosophila melanogaster
FBal0260454 Egfr[MI02852]   Drosophila melanogaster
FBal0245403 Egfr[JF01083]   Drosophila melanogaster
FBal0245404 Egfr[JF01084]   Drosophila melanogaster
FBal0245898 Egfr[JF01696]   Drosophila melanogaster
FBal0183724 Egfr[d04906]   Drosophila melanogaster
FBal0183725 Egfr[d00224]   Drosophila melanogaster
FBal0248858 Egfr[NIG.10079R]   Drosophila melanogaster
FBal0152531 Egfr[EPM865]   Drosophila melanogaster
FBal0065256 Egfr[k05115]   Drosophila melanogaster
FBal0065257 Egfr[03033] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0008087 Egfr[05351] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0043451 Egfr[09261]   Drosophila melanogaster
FBal0260786 Egfr[18.38]   Drosophila melanogaster
FBal0260787 Egfr[26.36]   Drosophila melanogaster
FBal0156482 Egfr[KG07633]   Drosophila melanogaster
FBal0192706 Egfr[EY22860]   Drosophila melanogaster
FBal0266602 Egfr[JF02283]   Drosophila melanogaster
FBal0266605 Egfr[JF02384]   Drosophila melanogaster
FBal0288699 Egfr[1a15]   Drosophila melanogaster
FBal0288700 Egfr[H25]   Drosophila melanogaster
FBal0219093 Egfr[Act.cUa.Scer\UAS]   Drosophila melanogaster
FBal0219094 Egfr[DN.cUa.Scer\UAS]   Drosophila melanogaster
FBal0066102 Egfr[unspecified]   Drosophila melanogaster
FBal0003543 Egfr[f15]   Drosophila melanogaster
FBal0033662 Egfr[mSa]   Drosophila melanogaster

47 Clones

Secondary Identifier DB identifier
EK146538 FBcl0044460
EK206248 FBcl0044520
EK181960 FBcl0045180
EK170641 FBcl0045440
EK172639 FBcl0045454
EK139817 FBcl0045486
EK278338 FBcl0045524
EK198615 FBcl0045540
EK274254 FBcl0045544
EK213764 FBcl0045564
EC13790 FBcl0066753
EP11336 FBcl0080719
EP08926 FBcl0081029
GH18982 FBcl0112467
HL03521 FBcl0149249
LP05058 FBcl0183028
LP11484 FBcl0183039
EC055435 FBcl0301605
EC052265 FBcl0302393
EC053755 FBcl0302394
EC054779 FBcl0302395
EC056026 FBcl0302396
EC056102 FBcl0302397
EC056239 FBcl0302398
EC056492 FBcl0302399
EC054262 FBcl0302400
EC052811 FBcl0302401
IP15102 FBcl0319540
FGM319F01 FBcl0393476
MIP13684 FBcl0718702

6 Exons

DB identifier Symbol
FBgn0003731:1 Egfr:1
FBgn0003731:3 Egfr:3
FBgn0003731:4 Egfr:4
FBgn0003731:5 Egfr:5
FBgn0003731:6 Egfr:6
FBgn0003731:2 Egfr:2

2 Transcripts

DB identifier Gene
FBtr0071653 Egfr
FBtr0071654 Egfr

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071653-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0071654-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071653-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071654-3-prime-utr Drosophila melanogaster

Interactions

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Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37455 NCBI Entrez Gene identifiers FBgn0003731
63083 BioGRID FBgn0003731

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 199.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 245.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 406.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 494.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 290.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 31.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 283.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 290.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 190.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 353.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 176.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 41.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 215.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 912.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 253.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 769.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 125.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 406.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 294.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 234.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 478.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 146.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 110.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 149.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 236.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 367.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1581.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1969.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1734.0
FBgn0003731 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1213.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0003731:1_FBgn0003731:3 Drosophila melanogaster
intron_FBgn0003731:3_FBgn0003731:4 Drosophila melanogaster
intron_FBgn0003731:4_FBgn0003731:5 Drosophila melanogaster
intron_FBgn0003731:5_FBgn0003731:6 Drosophila melanogaster
intron_FBgn0003731:2_FBgn0003731:3 Drosophila melanogaster

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Egfr none -0.05536733   19067489
Lipid storage Egfr none -1.125495339   19067489
Lipid storage Egfr none 1.478921734   19067489
Lipid storage Egfr none -0.061961562   19067489
Cell cycle regulation (1) Egfr none np   15616552
Cell cycle regulation (2) Egfr none np   15616552
Cell size and cell-cycle regulation (1) Egfr none sp   16496002
Embryonic nervous system development Egfr Defects in nervous system development np   15534205
Heart development and function Egfr Cardiac precursors specification defects np   14684833
Muscle morphogenesis and function (1) Egfr none np   20220848
Muscle morphogenesis and function (1) Egfr none np   20220848
Muscle morphogenesis and function (1) Egfr none np   20220848
Heat nociception (1) Egfr none -0.31   21074052
Heart development and function (1) Egfr none 1   20371351
Serratia marcescens infection (1) Egfr none -1.33333333333333   19520911
Serratia marcescens infection (2) Egfr Decreased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (4) Egfr none sp   19520911
Notch pathway regulation (4) Egfr Colour defects, notum malformation death sp   19363474
Notch pathway regulation (4) Egfr Colour defects, notum malformation death sp   19363474
PGN-induced dJNK phosphorylation Egfr Increased P-JNK protein expression with PGN 2.23 15 min PGN induction 19893628
Adiposity regulation (1) Egfr none -0.445   20074523
Blood cell homeostasis regulation (1) Egfr none np   20540764
Blood cell homeostasis regulation (2) Egfr none np   20540764
Actin organization and cell morphology (1) Egfr none np   19265526
Actin organization and cell morphology (2) Egfr none np   19265526
Actin organization and cell morphology (3) Egfr none np   19265526
Actin organization and cell morphology (4) Egfr none np   19265526
Actin organization and cell morphology (5) Egfr none np   19265526
Actin organization and cell morphology (6) Egfr none np   19265526
Vaccinia virus infection Egfr none sp   20585561

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