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Gene : slmb D. melanogaster

DB identifier  ? FBgn0023423 Secondary Identifier  ? CG3412
Name  ? supernumerary limbs Source  FlyBase
  • synonyms:
  • Supernumerary limbs,
  • Slimb/Beta-TRCP1,
  • shiva,
  • FBXW1,
  • SLMB,
  • centrosome replication defective,
  • crd,
  • ica,
  • SLIMB,
  • FBgn0023437,
  • icare,
  • pingiel,
  • shv,
  • BcDNA:GM02031,
  • FBgn0023423,
  • FBgn0016060,
  • CG3412,
  • Slimb/beta-TRCP,
  • FBgn0063206,
  • l(3)00295,
  • FBan0003412

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54 Alleles

DB identifier Symbol Allele Class Organism
FBal0267307 slmb[Scer\UAS.T:Zzzz\vhhGFP4]   Drosophila melanogaster
FBal0267308 slmb[Scer\UAS.attB.T:Zzzz\vhhGFP4]   Drosophila melanogaster
FBal0277625 slmb[Scer\UAS.T:Zzzz\FLAG,T:Hsap\MYC]   Drosophila melanogaster
FBal0284276 slmb[UU11]   Drosophila melanogaster
FBal0284277 slmb[3A1]   Drosophila melanogaster
FBal0177877 slmb[d02606]   Drosophila melanogaster
FBal0245765 slmb[JF01504]   Drosophila melanogaster
FBal0146793 slmb[pingiel]   Drosophila melanogaster
FBal0177876 slmb[d06758]   Drosophila melanogaster
FBal0215805 slmb[PBac4251]   Drosophila melanogaster
FBal0257518 slmb[HMS00838]   Drosophila melanogaster
FBal0177875 slmb[e01158]   Drosophila melanogaster
FBal0177878 slmb[c04914]   Drosophila melanogaster
FBal0257616 slmb[HMS00946]   Drosophila melanogaster
FBal0154578 slmb[EP681b]   Drosophila melanogaster
FBal0158664 slmb[EY09052]   Drosophila melanogaster
FBal0158665 slmb[A197]   Drosophila melanogaster
FBal0042404 slmb[04295]   Drosophila melanogaster
FBal0083748 slmb[00295] loss of function allele Drosophila melanogaster
FBal0285742 slmb[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0092523 slmb[05415]   Drosophila melanogaster
FBal0117352 slmb[P245]   Drosophila melanogaster
FBal0129066 slmb[EP662]   Drosophila melanogaster
FBal0104425 slmb[crd] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0092522 slmb[e4-1]   Drosophila melanogaster
FBal0117354 slmb[8]   Drosophila melanogaster
FBal0083750 slmb[1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0088645 slmb[alphaTub84B.PJ]   Drosophila melanogaster
FBal0092521 slmb[hs.PT]   Drosophila melanogaster
FBal0117353 slmb[L.hs]   Drosophila melanogaster

122 Clones

Secondary Identifier DB identifier
DPiM_LD08669 FBcl0741608
AT26894 FBcl0024041
AT09133 FBcl0024083
AT13547 FBcl0024091
bs79f01 FBcl0052055
bs02a08 FBcl0052605
CK00334 FBcl0059787
EC24281 FBcl0067445
EK220247 FBcl0074800
EK197907 FBcl0075092
EK293608 FBcl0075116
EK053660 FBcl0075136
EK094721 FBcl0075146
EK235610 FBcl0075162
EK146534 FBcl0075164
EK049528 FBcl0075338
GM03239 FBcl0141628
GM02031 FBcl0141661
LD08669 FBcl0155568
LD08103 FBcl0155578
LD31459 FBcl0169096
LD34338 FBcl0169097
LP03241 FBcl0184082
LP12437 FBcl0184110
RE11351 FBcl0210106
RE73153 FBcl0210111
RE17525 FBcl0210113
RE15220 FBcl0210114
RE59934 FBcl0210117
RE06784 FBcl0210120

9 Exons

DB identifier Symbol
FBgn0023423:3 slmb:3
FBgn0023423:1 slmb:1
FBgn0023423:9 slmb:9
FBgn0023423:8 slmb:8
FBgn0023423:7 slmb:7
FBgn0023423:6 slmb:6
FBgn0023423:5 slmb:5
FBgn0023423:4 slmb:4
FBgn0023423:2 slmb:2

3 Transcripts

DB identifier Gene
FBtr0330049 slmb
FBtr0333931 slmb
FBtr0084032 slmb

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084032-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333931-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330049-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084032-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333931-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330049-3-prime-utr Drosophila melanogaster

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48 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42504 NCBI Entrez Gene identifiers FBgn0023423
67475 BioGRID FBgn0023423

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2096.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2002.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1273.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1291.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1228.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 616.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1949.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1825.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 750.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1868.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1466.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 963.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1291.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1172.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1626.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1446.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1539.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1268.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1280.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1175.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1494.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1729.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1117.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1892.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1364.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6075.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2328.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3375.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2056.0
FBgn0023423 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2021.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0023423:9_FBgn0023423:8 Drosophila melanogaster
intron_FBgn0023423:8_FBgn0023423:7 Drosophila melanogaster
intron_FBgn0023423:7_FBgn0023423:6 Drosophila melanogaster
intron_FBgn0023423:6_FBgn0023423:5 Drosophila melanogaster
intron_FBgn0023423:5_FBgn0023423:4 Drosophila melanogaster
intron_FBgn0023423:4_FBgn0023423:3 Drosophila melanogaster
intron_FBgn0023423:3_FBgn0023423:1 Drosophila melanogaster
intron_FBgn0023423:3_FBgn0023423:2 Drosophila melanogaster

40 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage slmb none 0.26925203   19067489
Lipid storage slmb none -0.685889633   19067489
Cell morphology slmb Morphology np   14527345
Wnt signaling slmb Increased Wnt reporter activity 10.8   15817814
Hedgehog signaling slmb Increased Hedgehog reporter activity 3.38   16311596
Cell size and cell-cycle regulation (1) slmb none sp   16496002
Cell size and cell-cycle regulation (1) slmb none sp   16496002
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) slmb none 2.41   17267500
Microtubule assembly and organization slmb none np   18463163
Centriol duplication slmb Increased centrosome number 4.2 +/- 3.8   19171756
Combinatorial effect with methyl methanesulphonate (1) slmb Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) slmb Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) slmb Lethal np   20220848
Muscle morphogenesis and function (1) slmb Lethal np   20220848
Heat nociception (1) slmb none 1.25   21074052
Heat nociception (1) slmb Developmentally lethal 0   21074052
Heart development and function (1) slmb none 1   20371351
Serratia marcescens infection (1) slmb none -0.857142857142857   19520911
Serratia marcescens infection (1) slmb none -0.690265486725663   19520911
Notch pathway regulation (4) slmb Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) slmb Completely lethal (pupal) sp   19363474
Hh pathway regulation slmb none -0.0403496487194347   17903264
Hh pathway regulation slmb none 0.0513370108550825   17903264
Self-renewal and differentiation in neural stem cells slmb GFP aggregates number, GFP aggregates size, lethal sp   21549331
Notch pathway regulation (1) slmb Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) slmb none np en-GAL4 20493818
Notch pathway regulation (2) slmb none np en-GAL4 20493818
Notch pathway regulation (3) slmb Only lethal with Notch np   20493818
Adiposity regulation (1) slmb none -0.18   20074523
Blood cell homeostasis regulation (1) slmb none np   20540764

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