Genomics
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54 Alleles
122 Clones
9 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0023423:3 | slmb:3 |
| FBgn0023423:1 | slmb:1 |
| FBgn0023423:9 | slmb:9 |
| FBgn0023423:8 | slmb:8 |
| FBgn0023423:7 | slmb:7 |
| FBgn0023423:6 | slmb:6 |
| FBgn0023423:5 | slmb:5 |
| FBgn0023423:4 | slmb:4 |
| FBgn0023423:2 | slmb:2 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0084032-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333931-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0330049-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0084032-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333931-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0330049-3-prime-utr | Drosophila melanogaster |
Other
48 Pathways
- NOD1/2 Signaling Pathway,
- Cytokine Signaling in Immune system,
- Degradation of beta-catenin by the destruction complex,
- Mitotic G2-G2/M phases,
- Immune System,
- Regulation of mitotic cell cycle,
- Mitotic G1-G1/S phases,
- DNA Replication,
- Toll Like Receptor 10 (TLR10) Cascade,
- Toll Like Receptor 3 (TLR3) Cascade,
- Mitotic M-M/G1 phases,
- IRAK2 mediated activation of TAK1 complex,
- B Cell Activation,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- MyD88 dependent cascade initiated on endosome,
- TRIF-mediated TLR3/TLR4 signaling,
- Toll Like Receptor 5 (TLR5) Cascade,
- Activated TLR4 signalling,
- Toll Like Receptor 4 (TLR4) Cascade,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Regulation of APC/C activators between G1/S and early anaphase,
- Innate Immune System,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Cell Cycle, Mitotic,
- SCF-beta-TrCP mediated degradation of Emi1,
- MyD88 cascade initiated on plasma membrane,
- Toll Like Receptor TLR6:TLR2 Cascade,
- MyD88:Mal cascade initiated on plasma membrane,
- Signaling Pathways,
- Toll Like Receptor 9 (TLR9) Cascade,
- Toll-Like Receptors Cascades,
- Cell Cycle,
- Toll Like Receptor TLR1:TLR2 Cascade,
- Toll Like Receptor 2 (TLR2) Cascade,
- APC/C-mediated degradation of cell cycle proteins,
- Signaling by Wnt,
- Adaptive Immune System,
- Regulation of PLK1 Activity at G2/M Transition,
- Interleukin-1 signaling,
- Circadian Clock,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- Signaling by Interleukins,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex,
- Beta-catenin phosphorylation cascade,
- Activation of NF-kappaB in B Cells,
- G2/M Transition,
- MyD88-independent cascade
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 42504 | NCBI Entrez Gene identifiers | FBgn0023423 |
| 67475 | BioGRID | FBgn0023423 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
8 Introns
40 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | slmb | none | 0.26925203 | 19067489 | |
| Lipid storage | slmb | none | -0.685889633 | 19067489 | |
| Cell morphology | slmb | Morphology | np | 14527345 | |
| Wnt signaling | slmb | Increased Wnt reporter activity | 10.8 | 15817814 | |
| Hedgehog signaling | slmb | Increased Hedgehog reporter activity | 3.38 | 16311596 | |
| Cell size and cell-cycle regulation (1) | slmb | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | slmb | none | sp | 16496002 | |
| CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) | slmb | none | 2.41 | 17267500 | |
| Microtubule assembly and organization | slmb | none | np | 18463163 | |
| Centriol duplication | slmb | Increased centrosome number | 4.2 +/- 3.8 | 19171756 | |
| Combinatorial effect with methyl methanesulphonate (1) | slmb | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Combinatorial effect with methyl methanesulphonate (2) | slmb | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Muscle morphogenesis and function (1) | slmb | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | slmb | Lethal | np | 20220848 | |
| Heat nociception (1) | slmb | none | 1.25 | 21074052 | |
| Heat nociception (1) | slmb | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | slmb | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | slmb | none | -0.857142857142857 | 19520911 | |
| Serratia marcescens infection (1) | slmb | none | -0.690265486725663 | 19520911 | |
| Notch pathway regulation (4) | slmb | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | slmb | Completely lethal (pupal) | sp | 19363474 | |
| Hh pathway regulation | slmb | none | -0.0403496487194347 | 17903264 | |
| Hh pathway regulation | slmb | none | 0.0513370108550825 | 17903264 | |
| Self-renewal and differentiation in neural stem cells | slmb | GFP aggregates number, GFP aggregates size, lethal | sp | 21549331 | |
| Notch pathway regulation (1) | slmb | Upregulation of Notch pathway | np | 20493818 | |
| Notch pathway regulation (2) | slmb | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | slmb | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (3) | slmb | Only lethal with Notch | np | 20493818 | |
| Adiposity regulation (1) | slmb | none | -0.18 | 20074523 | |
| Blood cell homeostasis regulation (1) | slmb | none | np | 20540764 |
