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Gene : Nup160 D. melanogaster

DB identifier  ? FBgn0262647 Secondary Identifier  ? CG4738
Name  ? Nucleoporin 160kD Source  FlyBase
  • synonyms:
  • l(2)SH2055,
  • Nup160[mel],
  • FBan0004738,
  • Nucleoporin 160,
  • lethal (2) SH2055,
  • l(2)SH2 2055,
  • nup160,
  • FBgn0032347,
  • FBgn0250730,
  • CG4738,
  • FBgn0262647,
  • FBgn0065273,
  • FBgn0260937,
  • nuclear pore protein 160

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35 Alleles

DB identifier Symbol Allele Class Organism
FBal0277090 Nup160[EP372M206]   Drosophila melanogaster
FBal0277091 Nup160[EP372M230]   Drosophila melanogaster
FBal0277092 Nup160[EP372M241]   Drosophila melanogaster
FBal0277093 Nup160[EP372M18]   Drosophila melanogaster
FBal0277094 Nup160[EP372M25]   Drosophila melanogaster
FBal0277095 Nup160[EP372M54]   Drosophila melanogaster
FBal0277096 Nup160[EP372M55]   Drosophila melanogaster
FBal0277097 Nup160[EP372M64]   Drosophila melanogaster
FBal0277098 Nup160[EP372M75]   Drosophila melanogaster
FBal0277099 Nup160[EP372M121]   Drosophila melanogaster
FBal0277100 Nup160[EP372M123]   Drosophila melanogaster
FBal0277101 Nup160[EP372M85]   Drosophila melanogaster
FBal0277102 Nup160[EP372M161]   Drosophila melanogaster
FBal0277103 Nup160[EP372M26]   Drosophila melanogaster
FBal0277104 Nup160[EP372M39]   Drosophila melanogaster
FBal0277105 Nup160[EP372M94]   Drosophila melanogaster
FBal0277106 Nup160[EP372M133]   Drosophila melanogaster
FBal0277107 Nup160[EP372M142]   Drosophila melanogaster
FBal0277108 Nup160[EP372M185]   Drosophila melanogaster
FBal0277109 Nup160[EP372M215]   Drosophila melanogaster
FBal0277110 Nup160[EP372M227]   Drosophila melanogaster
FBal0277111 Nup160[EP372M180] amorphic allele - molecular evidence Drosophila melanogaster
FBal0277112 Nup160[EP372M69]   Drosophila melanogaster
FBal0220491 Nup160[e00704]   Drosophila melanogaster
FBal0220492 Nup160[Scer\UAS.cTa]   Drosophila melanogaster
FBal0259362 Nup160[KK104805]   Drosophila melanogaster
FBal0248147 Nup160[HMS00385]   Drosophila melanogaster
FBal0287436 Nup160[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287437 Nup160[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0212652 Nup160[dsRNA.cMa]   Drosophila melanogaster

46 Clones

Secondary Identifier DB identifier
AT15616 FBcl0032783
AT28280 FBcl0032805
AT04534 FBcl0032807
AT10915 FBcl0032815
AT29683 FBcl0032819
AT19016 FBcl0032821
AT03549 FBcl0032825
AT10345 FBcl0032831
AT19106 FBcl0032925
CK01477 FBcl0060147
EK125751 FBcl0094460
EK022808 FBcl0094542
EK063530 FBcl0094636
EK056420 FBcl0094670
EK192560 FBcl0094984
EK129951 FBcl0094990
EK200622 FBcl0094998
EK198024 FBcl0095004
EN05820 FBcl0098979
EN06041 FBcl0098985
GM10010 FBcl0142583
GM31401 FBcl0147262
LD22817 FBcl0178484
LD41363 FBcl0178495
LD32276 FBcl0178496
LD26377 FBcl0178497
LD39963 FBcl0178498
LD44873 FBcl0178499
LP03646 FBcl0191544
RE62717 FBcl0238100

15 Exons

DB identifier Symbol
FBgn0262647:1 Nup160:1
FBgn0262647:2 Nup160:2
FBgn0262647:3 Nup160:3
FBgn0262647:4 Nup160:4
FBgn0262647:5 Nup160:5
FBgn0262647:6 Nup160:6
FBgn0262647:7 Nup160:7
FBgn0262647:8 Nup160:8
FBgn0262647:9 Nup160:9
FBgn0262647:10 Nup160:10
FBgn0262647:11 Nup160:11
FBgn0262647:12 Nup160:12
FBgn0262647:13 Nup160:13
FBgn0262647:15 Nup160:15
FBgn0262647:14 Nup160:14

2 Transcripts

DB identifier Gene
FBtr0343613 Nup160
FBtr0080199 Nup160

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0343613-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080199-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0343613-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080199-3-prime-utr Drosophila melanogaster

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43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34549 NCBI Entrez Gene identifiers FBgn0262647
60611 BioGRID FBgn0262647

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

14 Introns

DB identifier
Organism . Name
intron_FBgn0262647:1_FBgn0262647:2 Drosophila melanogaster
intron_FBgn0262647:2_FBgn0262647:3 Drosophila melanogaster
intron_FBgn0262647:3_FBgn0262647:4 Drosophila melanogaster
intron_FBgn0262647:4_FBgn0262647:5 Drosophila melanogaster
intron_FBgn0262647:5_FBgn0262647:6 Drosophila melanogaster
intron_FBgn0262647:6_FBgn0262647:7 Drosophila melanogaster
intron_FBgn0262647:7_FBgn0262647:8 Drosophila melanogaster
intron_FBgn0262647:8_FBgn0262647:9 Drosophila melanogaster
intron_FBgn0262647:9_FBgn0262647:10 Drosophila melanogaster
intron_FBgn0262647:10_FBgn0262647:11 Drosophila melanogaster
intron_FBgn0262647:11_FBgn0262647:12 Drosophila melanogaster
intron_FBgn0262647:12_FBgn0262647:13 Drosophila melanogaster
intron_FBgn0262647:13_FBgn0262647:15 Drosophila melanogaster
intron_FBgn0262647:13_FBgn0262647:14 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Nup160 none -2.172505312   19067489
Lipid storage Nup160 none -1.39298324   19067489
Constitutive protein secretion and Golgi organization (1) Nup160 Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (2) Nup160 Fragmented Golgi membranes np   16452979
Cell size and cell-cycle regulation (1) Nup160 none sp   16496002
Mitochondrial biogenesis and function Nup160 Increased mitochondrial citrate synthase activity 1.357   18042644
Mutant human huntingtin aggregation Nup160 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Nup160 Lethal np   20220848
Heart development and function (1) Nup160 none 1   20371351
Serratia marcescens infection (1) Nup160 none 0   19520911
Notch pathway regulation (4) Nup160 Completely lethal (before pupal) sp   19363474
Adiposity regulation (1) Nup160 none -0.005   20074523
RTK-Ras-ERK pathway regulation (1) Nup160 Decreased ERK phosphorylation after EGF stimulation -1.63 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Nup160 Decreased ERK phosphorylation after EGF stimulation -3.12 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Nup160 none -0.34 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Nup160 none -0.34 10 minutes sSpitz stimulation 22028469
Wnt proteins secretion Nup160 none -0.1   22094269
Wg pathway regulation (1) Nup160 Decreased WgRluc and not changed sFluc protein expression weak   21886182
Wg pathway regulation (2) Nup160 Enhanced sev–wg rough-eye phenotype 1   21886182
Wg pathway regulation (3) Nup160 Pupal lethal np   21886182
Wg pathway regulation (4) Nup160 Pupal lethal np   21886182
Hippo pathway regulation Nup160 none -0.92   23263283
Glycosylation regulation (1) Nup160 none sp   21203496
Huntingtin (Htt) aggregates formation Nup160 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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